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Query: VCAM1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
VCAM1 1 3.598 1.250 -0.880 -0.412 -0.373

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
VCAM1 Phosphorylation S1255 2.400 _GDLETSNLQDMQS(ph)QEISGLKDCEIDAEEK_
VCAM1 Phosphorylation S834 1.282 _VDS(ph)LEFSLESQK_
VCAM1 Phosphorylation S3150 1.391 1.078 _VAQRS(ph)PVDSGTILR_
VCAM1 Phosphorylation S3175 1.052 0.884 _SVPVNNLPERS(ph)PTDSPR_
VCAM1 Ubiquitylation K657 -0.600 0.172 _TQQIK(gl)SHEYNER_
VCAM1 Ubiquitylation K606 0.112 _ALLSALELKK(gl)_
VCAM1 Ubiquitylation K2713 0.058 _MTAK(gl)ETELQR_
VCAM1 Phosphorylation S276 0.013 _RDANSSFFDNSSS(ph)PHLLDQLK_
VCAM1 Ubiquitylation K689 -0.011 _NLHNVLDSK(gl)SVEVETQK_
VCAM1 Ubiquitylation K770 -1.636 -0.056 _SK(gl)DASLVTNEDHQR_
VCAM1 Ubiquitylation K263 0.419 -0.113 _STLQIGK(gl)R_
VCAM1 Phosphorylation S1750 -1.171 -0.117 _S(ph)LLGIDTEDAIQGR_
VCAM1 Phosphorylation S1747 -0.145 _LQLQGLDLS(ph)SR_
VCAM1 Ubiquitylation K555 -0.739 -0.237 _INQQENSLTLEK(gl)LK_
VCAM1 Phosphorylation S3119 -0.975 -0.328 _LALS(ph)PLSLGK_
VCAM1 Ubiquitylation K293 -0.460 _NK(gl)INELELR_
VCAM1 Phosphorylation T1825 -0.475 _ITETGAVKPTGECSGEQSPDT(ph)NYEPPGEDK_
VCAM1 Ubiquitylation K823 -1.207 -0.686 _LEADQSPK(gl)NSAILQNR_
VCAM1 Ubiquitylation K326 -0.856 _FQELQLQLEKAK(gl)_
VCAM1 Phosphorylation S2996 -1.047 -1.005 _GS(ph)PLLGPVVPGPS(ph)PIPSVTEK_
VCAM1 Ubiquitylation K513 -1.965 _NIK(gl)QCLNQSQNFAEEMK_
VCAM1 Phosphorylation S3007 -0.910 -2.059 _GS(ph)PLLGPVVPGPS(ph)PIPSVTEK_
VCAM1 Ubiquitylation K1022 -0.770 _SISELSDQYKQEK(gl)_
VCAM1 Ubiquitylation K2069 -0.699 _GELDTMSKK(gl)_
VCAM1 Ubiquitylation K2739 -1.524 _TAELQEELSGEK(gl)NR_

Background Information for VCAM1:


Pubmed-VCAM1 »
Uniprot-VCAM1 »
Biogrid-VCAM1 »
ProteomicsDB-VCAM1 »

Tumorportal-VCAM1 »
COSMIC-VCAM1 »
GenomeRNAi-VCAM1 »
Genecards-VCAM1


Protein-protein Interactions for VCAM1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait VCAM1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in VCAM1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ig-like_dom IPR007110 0.6
Category members Ig_sub IPR003599 0.43
Category members Immunoglobulin IPR013151 0.23
Category members Ig_sub2 IPR003598 0.21
Category members Ig_I-set IPR013098 0.13
Category members Ig_V-set_subgr IPR003596 0
Category members ICAM_VCAM_N IPR003987 0
Category members Ig_C2-set IPR008424 0
Category members ICAM_N IPR013768 0


Protein complexes (CORUM database) featuring VCAM1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2421 ITGA4-ITGB1-VCAM1 complex Database 0
Category members Corum 2442 ITGA9-ITGB1-VCAM1 complex Database 0


Categories featuring VCAM1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005615 extracellular space Database 4.72
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members GO Category GO:0010212 response to ionizing radiation Database 1.66
Category members GO Category GO:0005769 early endosome Database 1.26
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_699 REACTOME_INTERFERON_SIGNALING 0 0.86
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0019221 cytokine-mediated signaling pathway Database 0.44
Category members GO Category GO:0042383 sarcolemma Database 0.36
Category members GO Category GO:0032496 response to lipopolysaccharide Database 0.35
Category members Pathway Pathway_505 REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM 0 0.33
Category members GO Category GO:0002102 podosome Database 0.3
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members Pathway Pathway_605 KEGG_LEUKOCYTE_TRANSENDOTHELIAL_MIGRATION 0 0.2
Category members GO Category GO:0009986 cell surface Database 0.17
Category members GO Category GO:0050901 leukocyte tethering or rolling Database 0.17
Category members Pathway Pathway_1125 PID_ANTHRAX_PATHWAY 0 0.15
Category members GO Category GO:0005902 microvillus Database 0.13
Category members GO Category GO:0045471 response to ethanol Database 0.1
Category members GO Category GO:0005178 integrin binding Database 0.09
Category members GO Category GO:0002526 acute inflammatory response Database 0.09
Category members GO Category GO:0035924 cellular response to vascular endothelial growth factor stimulus Database 0.06
Category members GO Category GO:0030175 filopodium Database 0.05
Category members GO Category GO:0007157 heterophilic cell-cell adhesion Database 0.04
Category members GO Category GO:0042102 positive regulation of T cell proliferation Database 0.04
Category members GO Category GO:0071356 cellular response to tumor necrosis factor Database 0.03
Category members GO Category GO:0009897 external side of plasma membrane Database 0
Category members Pathway Pathway_1024 PID_INTEGRIN_A4B1_PATHWAY 0 0
Category members Pathway Pathway_1027 PID_INTEGRIN1_PATHWAY 0 0
Category members Pathway Pathway_1122 BIOCARTA_LYM_PATHWAY 0 0
Category members Pathway Pathway_1123 BIOCARTA_LAIR_PATHWAY 0 0
Category members Pathway Pathway_1160 PID_INTEGRIN5_PATHWAY 0 0
Category members Pathway Pathway_1217 KEGG_CELL_ADHESION_MOLECULES_CAMS 0 0
Category members Pathway Pathway_1218 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL 0 0
Category members Pathway Pathway_1219 PID_INTEGRIN2_PATHWAY 0 0
Category members Pathway Pathway_426 PID_INTEGRIN_A9B1_PATHWAY 0 0
Category members Pathway Pathway_430 PID_TXA2PATHWAY 0 0
Category members Pathway Pathway_898 REACTOME_INTERFERON_GAMMA_SIGNALING 0 0
Category members Pathway Pathway_930 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS 0 0
Category members GO Category GO:0001666 response to hypoxia Database 0
Category members GO Category GO:0002544 chronic inflammatory response Database 0
Category members GO Category GO:0007155 cell adhesion Database 0
Category members GO Category GO:0007159 leukocyte cell-cell adhesion Database 0
Category members GO Category GO:0007507 heart development Database 0
Category members GO Category GO:0007568 aging Database 0
Category members GO Category GO:0007584 response to nutrient Database 0
Category members GO Category GO:0008131 primary amine oxidase activity Database 0
Category members GO Category GO:0009308 amine metabolic process Database 0
Category members GO Category GO:0010043 response to zinc ion Database 0
Category members GO Category GO:0016337 cell-cell adhesion Database 0
Category members GO Category GO:0022614 membrane to membrane docking Database 0
Category members GO Category GO:0030183 B cell differentiation Database 0
Category members GO Category GO:0035094 response to nicotine Database 0
Category members GO Category GO:0045177 apical part of cell Database 0
Category members GO Category GO:0050776 regulation of immune response Database 0
Category members GO Category GO:0050839 cell adhesion molecule binding Database 0
Category members GO Category GO:0060326 cell chemotaxis Database 0
Category members GO Category GO:0060333 interferon-gamma-mediated signaling pathway Database 0
Category members GO Category GO:0060669 embryonic placenta morphogenesis Database 0
Category members GO Category GO:0060710 chorio-allantoic fusion Database 0
Category members GO Category GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex Database 0
Category members GO Category GO:0071333 cellular response to glucose stimulus Database 0


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