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PID_INTEGRIN_A4B1_PATHWAY
(Pathway_1024)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
PRKAR1A 1 -0.550 0.230
PRKAR1A 1 -0.550 0.230
TLN1 1 -0.130 0.000 0.807 0.246 0.137
VCAM1 1 1.250 -0.880 -0.412 -0.373
PRKAR1B 1 0.660 -0.470
PRKAR1B 1 0.660 -0.470
PRKACA 0 0.380 -0.680 -1.005 -0.697 0.234 0.487
PXN 0 1.020 -0.760
GIT1 0 0.720 -0.330 -1.751 0.439
CD81 0 0.850 -0.400 0.408 0.204
ITGA4 0 -0.620 0.820
PTPRA 0 0.890 -0.870 0.212 1.021
RAC1 0 -0.580 1.580 0.486 -0.364 -0.568
ABI1 0 0.853 0.389
PRKACB 0 1.740 -1.200 -1.064
PRKACB 0 1.740 -1.200 -1.005 -0.697 0.234 0.487
ITGB1 0 0.390 -0.650 0.101 -0.036
JAM2 0 0.170 0.960
YWHAZ 0 0.880 -0.450 0.433 1.494 -0.337 0.631 0.064
ARF6 0 0.210 -0.560 0.456
CRK 0 -0.790 0.230
SRC 0 0.050 0.470 -0.031

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ABI1 Phosphorylation T179 -1.186 _TNPPT(ph)QKPPSPPMSGR_
ABI1 Phosphorylation S184 -1.237 -1.395 _TNPPTQKPPS(ph)PPMSGR_
ABI1 Phosphorylation T230 0.423 0.203 _T(ph)ASLNQRPR_
ABI1 Phosphorylation S232 0.057 0.186 _TAS(ph)LNQRPR_
ABI1 Phosphorylation S324 1.188 _HNS(ph)TTSSTSSGGYRR_
CD81 Ubiquitylation K182 -2.166 _QFYDQALQQAVVDDDANNAK(gl)AVVK_
CRK Phosphorylation S40 0.533 0.363 _DS(ph)STSPGDYVLSVSENSR_
CRK Phosphorylation S41 1.065 0.801 _DSS(ph)TSPGDYVLSVSENSR_
GIT1 Phosphorylation S374 1.018 1.475 _SLS(ph)SPTDNLELSLR_
GIT1 Phosphorylation S375 0.909 1.262 _SLSS(ph)PTDNLELSLR_
GIT1 Phosphorylation S401 0.624 0.935 _SQSDLDDQHDYDSVAS(ph)DEDTDQEPLR_
GIT1 Phosphorylation S423 0.332 0.924 _ARS(ph)MDSSDLSDGAVTLQEYLELKK_
GIT1 Phosphorylation S605 0.173 0.037 _HGS(ph)GADSDYENTQSGDPLLGLEGK_
ITGA4 Phosphorylation S1021 -0.095 1.014 _RDS(ph)WSYINSK_
ITGB1 Ubiquitylation K774 0.402 _MNAK(gl)WDTGENPIYK_
ITGB1 Ubiquitylation K784 -0.172 0.350 _WDTGENPIYK(gl)SAVTTVVNPK_
ITGB1 Ubiquitylation K794 0.755 0.604 _SAVTTVVNPK(gl)YEGK_
JAM2 Ubiquitylation K291 0.436 0.826 _ATTMSENDFK(gl)HTK_
PRKACA Ubiquitylation K30 -0.143 _AKEDFLKK(gl)_
PRKACA Ubiquitylation K93 0.839 0.714 _QIEHTLNEK(gl)R_
PRKACB Ubiquitylation K30 -0.143 _AKEDFLKK(gl)_
PRKACB Ubiquitylation K93 0.839 0.714 _QIEHTLNEK(gl)R_
PRKACB Phosphorylation T243 -0.835 _T(ph)WTLCGTPEYLAPEIILSK_
PRKACB Phosphorylation T245 -0.116 -0.102 _TWT(ph)LCGTPEYLAPEIILSK_
PRKAR1A Ubiquitylation K63 -1.895 _LEKEEAK(gl)QIQNLQK_
PRKAR1A Ubiquitylation K70 -0.869 0.073 _QIQNLQK(gl)AGTR_
PRKAR1A Phosphorylation S83 -0.969 -0.776 _EDEIS(ph)PPPPNPVVK_
PRKAR1A Ubiquitylation K92 -3.269 -2.395 _TDSREDEISPPPPNPVVK(gl)GR_
PRKAR1A Ubiquitylation K222 0.412 0.536 _TNVK(gl)LWGIDR_
PRKAR1A Ubiquitylation K244 -0.384 3.721 _K(gl)MYEEFLSK_
PRKAR1A Ubiquitylation K261 -0.886 _VSILESLDK(gl)WER_
PRKAR1A Ubiquitylation K346 0.329 _GPLK(gl)CVK_
PRKAR1A Ubiquitylation K349 -0.425 -0.103 _CVK(gl)LDRPR_
PRKAR1A Ubiquitylation K367 -0.939 0.044 _VLGPCSDILK(gl)R_
PRKAR1B Phosphorylation S3 0.185 0.343 _(ac)AS(ph)PPACPSEEDESLKGCELYVQLHGIQQVLK_
PRKAR1B Ubiquitylation K244 -0.384 3.721 _K(gl)MYEEFLSK_
PRKAR1B Ubiquitylation K346 0.329 _GPLK(gl)CVK_
PRKAR1B Ubiquitylation K349 -0.425 -0.103 _CVK(gl)LDRPR_
PTPRA Ubiquitylation K571 -0.065 _TGNLPANMK(gl)K_
PTPRA Ubiquitylation K572 0.007 -0.015 _TGNLPANMKK(gl)_
PXN Phosphorylation S85 -0.156 0.192 _FIHQQPQSSS(ph)PVYGSSAK_
PXN Phosphorylation T136 1.322 _SAEPSPTVMST(ph)SLGSNLSELDR_
PXN Phosphorylation S140 -0.291 -0.948 _SAEPSPTVM(ox)STSLGS(ph)NLSELDR_
PXN Phosphorylation S302 -0.167 _S(ph)SPGGQDEGGFMAQGK_
PXN Phosphorylation S303 -0.167 _S(ph)SPGGQDEGGFMAQGK_
PXN Phosphorylation S322 -1.234 _TGSSS(ph)PPGGPPKPGSQLDSMLGSLQSDLNK_
RAC1 Ubiquitylation K115 -1.745 -0.215 _AK(gl)WYPEVR_
RAC1 Ubiquitylation K142 0.492 _LDLRDDK(gl)DTIEK_
RAC1 Ubiquitylation K152 0.099 -0.292 _K(gl)LTPITYPQGLAMAK_
RAC1 Ubiquitylation K166 -0.981 -0.655 _LTPITYPQGLAMAK(gl)EIGAVK_
RAC1 Ubiquitylation K172 1.026 0.412 _EIGAVK(gl)YLECSALTQR_
RAC1 Ubiquitylation K185 -0.113 0.578 _GLK(gl)TVFDEAIR_
RAC1 Ubiquitylation K202 -1.379 -1.447 _AVLCPPPVK(gl)KR_
RAC1 Ubiquitylation K203 -1.708 -1.447 _AVLCPPPVKK(gl)_
SRC Phosphorylation S17 -0.604 -0.689 _S(ph)LEPAENVHGAGGGAFPASQTPSKPASADGHR_
SRC Phosphorylation S75 0.060 0.331 _LFGGFNSSDTVTS(ph)PQR_
TLN1 Ubiquitylation K334 -0.489 0.561 _LLGITK(gl)ECVM(ox)R_
TLN1 Phosphorylation S423 0.105 _DHFGLEGDEESTMLEDS(ph)VSPKK_
TLN1 Phosphorylation S425 -0.366 -0.322 _DHFGLEGDEESTMLEDSVS(ph)PKK_
TLN1 Ubiquitylation K869 -0.260 _ILADATAK(gl)MVEAAK_
TLN1 Ubiquitylation K1541 0.365 2.311 _EVANSTANLVK(gl)TIK_
TLN1 Ubiquitylation K2021 0.309 0.479 _EGILK(gl)TAK_
VCAM1 Ubiquitylation K263 0.419 -0.113 _STLQIGK(gl)R_
VCAM1 Phosphorylation S276 0.013 _RDANSSFFDNSSS(ph)PHLLDQLK_
VCAM1 Ubiquitylation K293 -0.460 _NK(gl)INELELR_
VCAM1 Ubiquitylation K326 -0.856 _FQELQLQLEKAK(gl)_
VCAM1 Ubiquitylation K513 -1.965 _NIK(gl)QCLNQSQNFAEEMK_
VCAM1 Ubiquitylation K555 -0.739 -0.237 _INQQENSLTLEK(gl)LK_
VCAM1 Ubiquitylation K606 0.112 _ALLSALELKK(gl)_
VCAM1 Ubiquitylation K657 -0.600 0.172 _TQQIK(gl)SHEYNER_
VCAM1 Ubiquitylation K689 -0.011 _NLHNVLDSK(gl)SVEVETQK_
VCAM1 Ubiquitylation K770 -1.636 -0.056 _SK(gl)DASLVTNEDHQR_
VCAM1 Ubiquitylation K823 -1.207 -0.686 _LEADQSPK(gl)NSAILQNR_
VCAM1 Phosphorylation S834 1.282 _VDS(ph)LEFSLESQK_
VCAM1 Ubiquitylation K1022 -0.770 _SISELSDQYKQEK(gl)_
VCAM1 Phosphorylation S1255 2.400 _GDLETSNLQDMQS(ph)QEISGLKDCEIDAEEK_
VCAM1 Phosphorylation S1747 -0.145 _LQLQGLDLS(ph)SR_
VCAM1 Phosphorylation S1750 -1.171 -0.117 _S(ph)LLGIDTEDAIQGR_
VCAM1 Phosphorylation T1825 -0.475 _ITETGAVKPTGECSGEQSPDT(ph)NYEPPGEDK_
VCAM1 Ubiquitylation K2069 -0.699 _GELDTMSKK(gl)_
VCAM1 Ubiquitylation K2713 0.058 _MTAK(gl)ETELQR_
VCAM1 Ubiquitylation K2739 -1.524 _TAELQEELSGEK(gl)NR_
VCAM1 Phosphorylation S2996 -1.047 -1.005 _GS(ph)PLLGPVVPGPS(ph)PIPSVTEK_
VCAM1 Phosphorylation S3007 -0.910 -2.059 _GS(ph)PLLGPVVPGPS(ph)PIPSVTEK_
VCAM1 Phosphorylation S3119 -0.975 -0.328 _LALS(ph)PLSLGK_
VCAM1 Phosphorylation S3150 1.391 1.078 _VAQRS(ph)PVDSGTILR_
VCAM1 Phosphorylation S3175 1.052 0.884 _SVPVNNLPERS(ph)PTDSPR_
YWHAZ Ubiquitylation K3 0.268 0.388 _(ac)MDK(gl)NELVQK_
YWHAZ Ubiquitylation K9 0.917 0.954 _(ac)MDKNELVQK(gl)AK_
YWHAZ Ubiquitylation K11 0.016 0.388 _AK(gl)LAEQAERYDDMAACMK_
YWHAZ Ubiquitylation K49 0.656 1.019 _NLLSVAYK(gl)NVVGAR_
YWHAZ Ubiquitylation K68 0.504 _VVSSIEQK(gl)TEGAEK_
YWHAZ Ubiquitylation K74 0.762 _VVSSIEQKTEGAEK(gl)K_
YWHAZ Ubiquitylation K85 -0.089 _EK(gl)IETELR_
YWHAZ Ubiquitylation K122 0.498 0.837 _MK(gl)GDYYR_
YWHAZ Ubiquitylation K138 0.560 1.003 _YLAEVAAGDDK(gl)K_
YWHAZ Ubiquitylation K139 0.551 1.003 _YLAEVAAGDDKK(gl)_
YWHAZ Ubiquitylation K166 -0.439 -0.371 _K(gl)EMQPTHPIR_


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