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Query: ARF6

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ARF6 0 0.456 0.210 -0.560 0.456

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for ARF6:


Pubmed-ARF6 »
Uniprot-ARF6 »
Biogrid-ARF6 »
ProteomicsDB-ARF6 »

Tumorportal-ARF6 »
COSMIC-ARF6 »
GenomeRNAi-ARF6 »
Genecards-ARF6


Protein-protein Interactions for ARF6
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait GPAA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPL38 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MUC20 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MYADM Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PDCD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PDE4DIP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRNP27 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TBC1D22B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TGOLN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait THTPA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSPAN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait YAF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ARF6
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Small_GTPase_ARF/SAR IPR006689 0.8
Category members Small_GTPase IPR001806 0.65
Category members Gtr1_RagA IPR006762 0.63
Category members Small_GTPase_Rab_type IPR003579 0.51
Category members MIRO-like IPR013684 0.4
Category members Small_GTP-bd_dom IPR005225 0.32
Category members SRP_receptor_beta_su IPR019009 0.13
Category members Gprotein_alpha_su IPR001019 0.02
Category members Small_GTPase_SAR1 IPR006687 0
Category members Small_GTPase_ARF IPR024156 0


Protein complexes (CORUM database) featuring ARF6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ARF6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0015031 protein transport Database 3.48
Category members Pathway Pathway_292 PID_ECADHERIN_NASCENT_AJ_PATHWAY 0 2.74
Category members GO Category GO:0006886 intracellular protein transport Database 2.48
Category members GO Category GO:0005938 cell cortex Database 2.26
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members GO Category GO:0007186 G-protein coupled receptor signaling pathway Database 1.53
Category members Pathway Pathway_466 PID_ECADHERIN_STABILIZATION_PATHWAY 0 1.4
Category members GO Category GO:0005769 early endosome Database 1.26
Category members Pathway Pathway_666 KEGG_ENDOCYTOSIS 0 1.25
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0016192 vesicle-mediated transport Database 1.1
Category members Pathway Pathway_295 PID_ARF6_TRAFFICKING_PATHWAY 0 0.9
Category members GO Category GO:0030866 cortical actin cytoskeleton organization Database 0.89
Category members Pathway Pathway_507 PID_MET_PATHWAY 0 0.82
Category members GO Category GO:0031527 filopodium membrane Database 0.74
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0001889 liver development Database 0.51
Category members Pathway Pathway_992 PID_ARF6_PATHWAY 0 0.46
Category members GO Category GO:0007264 small GTPase mediated signal transduction Database 0.37
Category members GO Category GO:0001726 ruffle Database 0.33
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0005768 endosome Database 0.29
Category members GO Category GO:0006184 GTP catabolic process Database 0.29
Category members GO Category GO:0055037 recycling endosome Database 0.29
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0006928 cellular component movement Database 0.24
Category members GO Category GO:0030838 positive regulation of actin filament polymerization Database 0.21
Category members Pathway Pathway_294 PID_AJDISS_2PATHWAY 0 0.18
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members GO Category GO:0003924 GTPase activity Database 0.16
Category members Pathway Pathway_499 KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS 0 0.1
Category members Pathway Pathway_296 PID_ARF6_DOWNSTREAM_PATHWAY 0 0.08
Category members GO Category GO:0019001 guanyl nucleotide binding Database 0.07
Category members GO Category GO:0051489 regulation of filopodium assembly Database 0.04
Category members GO Category GO:0031683 G-protein beta/gamma-subunit complex binding Database 0.02
Category members Pathway Pathway_1024 PID_INTEGRIN_A4B1_PATHWAY 0 0
Category members Pathway Pathway_502 PID_PI3KCI_PATHWAY 0 0
Category members GO Category GO:0004871 signal transducer activity Database 0
Category members GO Category GO:0007155 cell adhesion Database 0
Category members GO Category GO:0030139 endocytic vesicle Database 0
Category members GO Category GO:0031529 ruffle organization Database 0
Category members GO Category GO:0031996 thioesterase binding Database 0
Category members GO Category GO:0034394 protein localization to cell surface Database 0
Category members GO Category GO:0035020 regulation of Rac protein signal transduction Database 0
Category members GO Category GO:0036010 protein localization to endosome Database 0
Category members GO Category GO:0048261 negative regulation of receptor-mediated endocytosis Database 0
Category members GO Category GO:0055038 recycling endosome membrane Database 0
Category members GO Category GO:0060998 regulation of dendritic spine development Database 0


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