RNAi screen result	RNAPII IP (MG132)	CSB IP	CSB IP (MG132)	Chrom.	Chrom. (MG132)	Ubi /Phospo	Ubi /Phospho (MG132)
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Gene name	MGoogle Score	RNAi high	RNAi low	RNAPII-IP (MG132)	CSB-IP	CSB-IP (MG132)	Chrom.	Chrom. (MG132)
HSP90AA1	3	-0.150	0.150	0.395	1.024	-1.280	0.611	0.460
HSP90AA1	3	0.170	-0.420	0.395	1.024	-1.280	0.611	0.460
FOXO3	2	-0.410	-0.120
ARF5	1	0.360	-0.510	1.771
ARF5	1	0.360	-0.510		0.702	-1.163
ARF5	1	0.360	-0.510	-0.334			0.348	-0.014
FYN	1	1.080	-1.100
FYN	1	1.080	-1.100
PIK3R2	1	2.740	-1.180				0.269	0.348
PLCG1	1	-0.170	0.000
KRAS	1	-0.510	0.620				1.031	0.887
KRAS	1	-0.510	0.620				0.246	-0.346
NRAS	1	1.810	-0.720				0.246	-0.346
LYN	1	-1.790	3.770
LYN	1	-1.790	3.770
ARF1	0	0.020	0.040	-0.334			0.348	-0.014
ARF3	0	-0.710	0.680	-0.334			0.348	-0.014
ARF4	0	0.190	-0.710	-0.334			0.348	-0.014
PIK3CB	0	-1.390	2.350
PIK3CB	0	-0.710	1.450
RHOA	0	-0.510	1.370	-0.485			0.532	0.279
PLEKHA1	0	-0.130	0.730
PLEKHA1	0	-0.130	0.730
PLEKHA1	0	-0.130	0.730
PIK3R3	0	-0.140	-0.480
PIK3R3	0	-0.140	-0.480				-0.441	0.147
PIK3CA	0
RAC1	0	-0.580	1.580	0.486			-0.364	-0.568
PDPK1	0	0.050	-0.440
ARF1	0	0.020	0.040		0.702	-1.163
PIK3R1	0	1.910	-1.220				-0.441	0.147
INPPL1	0	1.690	-0.810
ARF6	0	0.210	-0.560				0.456
HRAS	0	1.470	-0.520
YES1	0	0.340	-0.470				0.295	0.576
LCK	0	-0.490	1.390				0.295	0.576
SRC	0	0.050	0.470	-0.031

Gene name	PTM type	PTM site	UV	UV (MG132)	Sequence
FOXO3	Phosphorylation	S12		-1.324	_(ac)AEAPASPAPLS(ph)PLEVELDPEFEPQSRPR_
FOXO3	Phosphorylation	S253		2.510	_AVS(ph)MDNSNKYTK_
FOXO3	Phosphorylation	S284	4.138	6.011	_AALQTAPESADDS(ph)PSQLSK_
FOXO3	Phosphorylation	S421		1.295	_GS(ph)GLGSPTSSFNSTVFGPSSLNSLR_
FOXO3	Phosphorylation	S425		1.471	_GSGLGS(ph)PTSSFNSTVFGPSSLNSLR_
FYN	Ubiquitylation	K13	0.286		_DKEATK(gl)LTEER_
FYN	Phosphorylation	S21	0.373	0.731	_DGS(ph)LNQSSGYR_
FYN	Ubiquitylation	K259		0.921	_LTDLSVK(gl)TK_
FYN	Ubiquitylation	K261	0.099		_LTDLSVKTK(gl)_
FYN	Ubiquitylation	K273	6.025		_SLCLEKK(gl)_
FYN	Ubiquitylation	K275	-0.521		_ESLQLIK(gl)R_
HRAS	Ubiquitylation	K170	-1.005		_K(gl)LNPPDESGPGCMSCK_
HSP90AA1	Ubiquitylation	K69	0.820	-0.090	_YESLTDPSK(gl)LDSGK_
HSP90AA1	Ubiquitylation	K74	0.543		_LDSGK(gl)ELHINLIPNKQDR_
HSP90AA1	Ubiquitylation	K112	1.304	1.601	_ADLINNLGTIAK(gl)SGTK_
HSP90AA1	Ubiquitylation	K185	0.963		_GTK(gl)VILHLK_
HSP90AA1	Ubiquitylation	K208	1.745		_IKEIVK(gl)K_
HSP90AA1	Phosphorylation	S231	2.338	0.649	_DKEVS(ph)DDEAEEK_
HSP90AA1	Phosphorylation	S263	0.095	0.173	_ESEDKPEIEDVGS(ph)DEEEEKK_
HSP90AA1	Ubiquitylation	K281	1.267		_IK(gl)EKYIDQEELNK_
HSP90AA1	Ubiquitylation	K283	1.442	1.226	_EK(gl)YIDQEELNK_
HSP90AA1	Ubiquitylation	K292	-0.237	0.506	_YIDQEELNK(gl)TKPIWTR_
HSP90AA1	Ubiquitylation	K294	0.315	8.646	_TK(gl)PIWTR_
HSP90AA1	Ubiquitylation	K362	0.969	0.946	_NNIK(gl)LYVR_
HSP90AA1	Ubiquitylation	K407	0.827	1.121	_EMLQQSK(gl)ILK_
HSP90AA1	Ubiquitylation	K443	0.820	0.951	_FYEQFSK(gl)NIK_
HSP90AA1	Ubiquitylation	K446	0.314	1.126	_NIK(gl)LGIHEDSQNR_
HSP90AA1	Ubiquitylation	K478	0.799	1.624	_YYTSASGDEM(ox)VSLK(gl)DYCTR_
HSP90AA1	Ubiquitylation	K539	0.353	1.775	_EFEGK(gl)TLVSVTK_
HSP90AA1	Ubiquitylation	K559	-0.316		_EGLELPEDEEEKK(gl)K_
HSP90AA1	Ubiquitylation	K565	0.903		_K(gl)TKFENLCK_
HSP90AA1	Ubiquitylation	K567	0.710		_TK(gl)FENLCK_
HSP90AA1	Ubiquitylation	K576	0.874		_IMK(gl)DILEK_
HSP90AA1	Ubiquitylation	K581	0.540	0.738	_DILEK(gl)KVEK_
HSP90AA1	Ubiquitylation	K582	0.063	0.470	_K(gl)VEKVVVSNR_
HSP90AA1	Ubiquitylation	K615	0.715	0.751	_IMK(gl)AQALR_
HSP90AA1	Ubiquitylation	K631	0.361	0.974	_DNSTMGYMAAK(gl)K_
INPPL1	Phosphorylation	S1003	-1.290		_NSFNNPAYYVLEGVPHQLLPPEPPS(ph)PAR_
KRAS	Ubiquitylation	K128	1.528	1.433	_TVDTK(gl)QAHELAK_
KRAS	Ubiquitylation	K235	0.591	0.087	_TVDTK(gl)QAQDLAR_
KRAS	Ubiquitylation	K254	-0.450	-0.156	_SYGIPFIETSAK(gl)TR_
LCK	Phosphorylation	T37		-0.435	_YRPENTPEPVSTSVSHYGAEPT(ph)TVSPCPSSSAK_
LCK	Ubiquitylation	K191	-0.112	0.264	_ESETTK(gl)GAYSLSIR_
LCK	Ubiquitylation	K235	0.323		_AQFDTLQK(gl)LVK_
LCK	Ubiquitylation	K259		-1.613	_LTTVCPTVK(gl)PQTQGLAK_
LYN	Ubiquitylation	K20	-0.592		_GKDSLSDDGVDLK(gl)TQPVR_
LYN	Ubiquitylation	K40	0.100		_DPTSNK(gl)QQRPVPESQLLPGQR_
LYN	Phosphorylation	S104	0.944	0.841	_DSLS(ph)DDGVDLK_
LYN	Ubiquitylation	K213	0.441		_HYQK(gl)QADGLCR_
LYN	Ubiquitylation	K477	-0.191		_VENCPDELYDIMK(gl)MCWK_
NRAS	Ubiquitylation	K128	1.528	1.433	_TVDTK(gl)QAHELAK_
PDPK1	Phosphorylation	S241	0.358	0.361	_ANS(ph)FVGTAQYVSPELLTEK_
PDPK1	Ubiquitylation	K257	0.571	-0.234	_ANSFVGTAQYVSPELLTEK(gl)SACK_
PIK3CA	Ubiquitylation	K864	0.390	0.588	_NSHTIM(ox)QIQCK(gl)GGLK_
PIK3CA	Ubiquitylation	K868	0.204	0.651	_NSHTIM(ox)QIQCKGGLK(gl)_
PIK3CA	Ubiquitylation	K974	-0.273		_GAQECTK(gl)TREFER_
PIK3CB	Ubiquitylation	K1044		0.990	_SEEEALKQFKQK(gl)_
PIK3R2	Phosphorylation	S262		-2.237	_APPPPS(ph)SPPPGGAPDGSEPSPDFPALLVEK_
PIK3R2	Phosphorylation	S263		-2.237	_APPPPS(ph)SPPPGGAPDGSEPSPDFPALLVEK_
PIK3R2	Ubiquitylation	K500	-0.189		_IFEEQGQTQEK(gl)CSK_
PIK3R2	Ubiquitylation	K541	-0.609		_TK(gl)LEQQLR_
PIK3R2	Ubiquitylation	K564	-0.431	-1.022	_MNSLK(gl)PDLMQLR_
PIK3R3	Ubiquitylation	K226		-0.376	_YQQDQLVKEDNIDAVGKK(gl)_
PIK3R3	Ubiquitylation	K320		0.385	_LGEIHDSK(gl)MR_
PLCG1	Ubiquitylation	K300		8.031	_DLK(gl)NMLSQVNYR_
PLCG1	Ubiquitylation	K348		-0.219	_SLMYSAQK(gl)TMDLPFLEASTLR_
PLCG1	Ubiquitylation	K552		-0.355	_NMAQYFK(gl)K_
PLCG1	Ubiquitylation	K553		-0.355	_NMAQYFK(gl)K_
PLCG1	Ubiquitylation	K1063	0.864	0.355	_LTEGK(gl)IMER_
PLCG1	Phosphorylation	S1370	0.475	0.515	_AREGS(ph)FESR_
PLEKHA1	Ubiquitylation	K229	-0.332		_SELEK(gl)EPLR_
PLEKHA1	Phosphorylation	S308	0.664	0.154	_RLS(ph)NPCIQR_
PLEKHA1	Phosphorylation	S332	0.540		_SNS(ph)LVSTFTM(ox)EK_
RAC1	Ubiquitylation	K115	-1.745	-0.215	_AK(gl)WYPEVR_
RAC1	Ubiquitylation	K142	0.492		_LDLRDDK(gl)DTIEK_
RAC1	Ubiquitylation	K152	0.099	-0.292	_K(gl)LTPITYPQGLAMAK_
RAC1	Ubiquitylation	K166	-0.981	-0.655	_LTPITYPQGLAMAK(gl)EIGAVK_
RAC1	Ubiquitylation	K172	1.026	0.412	_EIGAVK(gl)YLECSALTQR_
RAC1	Ubiquitylation	K185	-0.113	0.578	_GLK(gl)TVFDEAIR_
RAC1	Ubiquitylation	K202	-1.379	-1.447	_AVLCPPPVK(gl)KR_
RAC1	Ubiquitylation	K203	-1.708	-1.447	_AVLCPPPVKK(gl)_
RHOA	Ubiquitylation	K6	0.708		_K(gl)KLVIVGDGACGK_
RHOA	Ubiquitylation	K7	0.708		_K(gl)KLVIVGDGACGK_
RHOA	Ubiquitylation	K118	-0.408		_HFCPNVPIILVGNK(gl)K_
RHOA	Ubiquitylation	K119	-0.408		_HFCPNVPIILVGNK(gl)K_
RHOA	Ubiquitylation	K135	-0.528	-0.796	_MK(gl)QEPVKPEEGRDMANR_
RHOA	Ubiquitylation	K162	0.345	0.453	_IGAFGYMECSAK(gl)TK_
SRC	Phosphorylation	S17	-0.604	-0.689	_S(ph)LEPAENVHGAGGGAFPASQTPSKPASADGHR_
SRC	Phosphorylation	S75	0.060	0.331	_LFGGFNSSDTVTS(ph)PQR_
YES1	Phosphorylation	T37		-0.435	_YRPENTPEPVSTSVSHYGAEPT(ph)TVSPCPSSSAK_
YES1	Ubiquitylation	K191	-0.112	0.264	_ESETTK(gl)GAYSLSIR_
YES1	Ubiquitylation	K235	0.323		_AQFDTLQK(gl)LVK_
YES1	Ubiquitylation	K259		-1.613	_LTTVCPTVK(gl)PQTQGLAK_