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Query: PLEKHA1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PLEKHA1 0 1.216 -0.130 0.730

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PLEKHA1 Phosphorylation S308 0.664 0.154 _RLS(ph)NPCIQR_
PLEKHA1 Phosphorylation S332 0.540 _SNS(ph)LVSTFTM(ox)EK_
PLEKHA1 Ubiquitylation K229 -0.332 _SELEK(gl)EPLR_

Background Information for PLEKHA1:





Protein-protein Interactions for PLEKHA1

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PLEKHA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPP1R15A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PLEKHA1

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PH_domain IPR001849 0.14


Protein complexes (CORUM database) featuring PLEKHA1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PLEKHA1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0032587 ruffle membrane Database 0.65
Category members GO Category GO:0008585 female gonad development Database 0.64
Category members GO Category GO:0001553 luteinization Database 0.31
Category members GO Category GO:0030165 PDZ domain binding Database 0.29
Category members GO Category GO:0060021 palate development Database 0.23
Category members GO Category GO:0045184 establishment of protein localization Database 0.1
Category members GO Category GO:0008210 estrogen metabolic process Database 0.07
Category members GO Category GO:0035264 multicellular organism growth Database 0.04
Category members GO Category GO:0070301 cellular response to hydrogen peroxide Database 0
Category members Pathway Pathway_502 PID_PI3KCI_PATHWAY 0 0
Category members GO Category GO:0007283 spermatogenesis Database 0
Category members GO Category GO:0008209 androgen metabolic process Database 0
Category members GO Category GO:0009791 post-embryonic development Database 0
Category members GO Category GO:0014065 phosphatidylinositol 3-kinase signaling Database 0
Category members GO Category GO:0031529 ruffle organization Database 0
Category members GO Category GO:0033327 Leydig cell differentiation Database 0
Category members GO Category GO:0043325 phosphatidylinositol-3,4-bisphosphate binding Database 0
Category members GO Category GO:0048008 platelet-derived growth factor receptor signaling pathway Database 0
Category members GO Category GO:0048705 skeletal system morphogenesis Database 0
Category members GO Category GO:0050853 B cell receptor signaling pathway Database 0
Category members GO Category GO:0051898 negative regulation of protein kinase B signaling Database 0
Category members GO Category GO:0060325 face morphogenesis Database 0


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