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phosphatidylinositol 3-kinase signaling
(GO:0014065)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
TSC2 1 0.810 -0.710
TSC2 1 0.810 -0.710 -0.715
IGF1R 1 -0.490 0.750 1.476 0.714
PIK3CB 0 -1.390 2.350
PIK3CB 0 -0.710 1.450
TYRO3 0 0.220 -0.340
GATA3 0 0.000 -0.660
PLEKHA1 0 -0.130 0.730
PLEKHA1 0 -0.130 0.730
PLEKHA1 0 -0.130 0.730
C1QBP 0 1.100 -0.820 0.115 -0.813 0.337 0.378
C1QBP 0 1.100 -0.820 -0.487
ERBB2 0 -1.310 1.360
PIK3R1 0 1.910 -1.220 -0.441 0.147
IRS1 0
NF1 0 1.000 -0.500 0.444 -0.190

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ERBB2 Ubiquitylation K200 -2.073 _ACHPCSPMCK(gl)GSR_
ERBB2 Ubiquitylation K369 -0.742 _AVTSANIQEFAGCKK(gl)_
ERBB2 Ubiquitylation K747 -0.505 -0.019 _GIWIPDGENVK(gl)IPVAIK_
ERBB2 Ubiquitylation K854 -0.859 _NVLVK(gl)SPNHVK_
ERBB2 Phosphorylation S1054 -0.476 -0.706 _S(ph)GGGDLTLGLEPSEEEAPR_
GATA3 Phosphorylation S162 -1.195 -0.563 _DVS(ph)PDPSLSTPGSAGSAR_
IGF1R Ubiquitylation K47 1.146 _NDYQQLK(gl)R_
IGF1R Ubiquitylation K1033 5.779 _VAIK(gl)TVNEAASMR_
IGF1R Ubiquitylation K1168 0.191 _K(gl)GGKGLLPVR_
IGF1R Ubiquitylation K1171 0.232 _GGK(gl)GLLPVR_
IRS1 Phosphorylation S1101 -0.078 _HSS(ph)ETFSSTPSATR_
NF1 Ubiquitylation K471 0.218 _MAPSLTFKEK(gl)_
NF1 Phosphorylation S864 -0.458 _SNSGLATYS(ph)PPMGPVSER_
NF1 Phosphorylation T2514 0.076 _GSEGYLAATYPTVGQT(ph)SPR_
NF1 Phosphorylation S2515 0.071 0.316 _GSEGYLAATYPTVGQTS(ph)PR_
NF1 Phosphorylation S2543 0.698 0.655 _S(ph)FDHLISDTK_
PIK3CB Ubiquitylation K1044 0.990 _SEEEALKQFKQK(gl)_
PLEKHA1 Ubiquitylation K229 -0.332 _SELEK(gl)EPLR_
PLEKHA1 Phosphorylation S308 0.664 0.154 _RLS(ph)NPCIQR_
PLEKHA1 Phosphorylation S332 0.540 _SNS(ph)LVSTFTM(ox)EK_
TSC2 Ubiquitylation K3 -1.397 _(ac)AK(gl)PTSKDSGLK_
TSC2 Ubiquitylation K14 -1.297 _DSGLKEK(gl)FK_
TSC2 Ubiquitylation K69 0.051 _MIGQICEVAK(gl)TK_
TSC2 Ubiquitylation K71 -0.157 _MIGQICEVAKTK(gl)_
TSC2 Ubiquitylation K258 -0.278 _ELCEPCWK(gl)LMR_
TSC2 Ubiquitylation K634 1.610 _LGLPNK(gl)DGVVR_
TSC2 Phosphorylation S950 -0.152 -0.529 _STS(ph)LNERPK_
TSC2 Phosphorylation S1064 -0.927 _SLLGLDSGELQSGPESSSS(ph)PGVHVR_
TSC2 Phosphorylation S1248 -0.604 _SNTDSAVVMEEGS(ph)PGEVPVLVEPPGLEDVEAALGMDRR_
TSC2 Phosphorylation S1329 -0.120 _S(ph)SSSPELQTLQDILGDPGDK_
TSC2 Phosphorylation S1331 -0.262 _SSS(ph)SPELQTLQDILGDPGDKADVGR_
TSC2 Phosphorylation S1332 -0.063 _SSSS(ph)PELQTLQDILGDPGDK_
TSC2 Phosphorylation S1355 0.174 0.351 _ADVGRLS(ph)PEVK_
TSC2 Phosphorylation S1362 0.859 _S(ph)QSGTLDGESAAWSASGEDSR_
TSC2 Phosphorylation S1364 0.522 0.550 _SQS(ph)GTLDGESAAWSASGEDSR_
TSC2 Phosphorylation T1366 0.137 _SQSGT(ph)LDGESAAWSASGEDSR_
TSC2 Phosphorylation S1396 0.498 _S(ph)PSGLRPR_
TSC2 Phosphorylation S1743 0.596 _RLISS(ph)VEDFTEFV_
TYRO3 Phosphorylation S930 0.766 -0.051 _YILTPGGLAEQPGQAEHQPES(ph)PLNETQR_


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