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Query: CD81

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CD81 0 -1.554 0.850 -0.400 0.408 0.204

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CD81 Ubiquitylation K182 -2.166 _QFYDQALQQAVVDDDANNAK(gl)AVVK_

Background Information for CD81:


Pubmed-CD81 »
Uniprot-CD81 »
Biogrid-CD81 »
ProteomicsDB-CD81 »

Tumorportal-CD81 »
COSMIC-CD81 »
GenomeRNAi-CD81 »
Genecards-CD81


Protein-protein Interactions for CD81
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in CD81
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Tetraspanin IPR000301 0
Category members Tetraspanin_EC2 IPR008952 0
Category members Tetraspanin/Peripherin IPR018499 0


Protein complexes (CORUM database) featuring CD81
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 117 GPR56-CD81-Galphaq/11-Gbeta complex Database 0
Category members Corum 2419 ITGA4-ITGB1-CD81 complex Database 0


Categories featuring CD81
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0008104 protein localization Database 0.5
Category members Pathway Pathway_535 SIG_BCR_SIGNALING_PATHWAY 0 0.24
Category members Pathway Pathway_648 KEGG_B_CELL_RECEPTOR_SIGNALING_PATHWAY 0 0.19
Category members GO Category GO:0008283 cell proliferation Database 0.06
Category members GO Category GO:0006661 phosphatidylinositol biosynthetic process Database 0.06
Category members GO Category GO:0046718 viral entry into host cell Database 0.04
Category members Pathway Pathway_1024 PID_INTEGRIN_A4B1_PATHWAY 0 0
Category members Pathway Pathway_1027 PID_INTEGRIN1_PATHWAY 0 0
Category members Pathway Pathway_1218 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL 0 0
Category members Disease phenotype Common_variable_immunodeficiency Common variable immunodeficiency Database 0
Category members GO Category GO:0000187 activation of MAPK activity Database 0
Category members GO Category GO:0001772 immunological synapse Database 0
Category members GO Category GO:0008284 positive regulation of cell proliferation Database 0
Category members GO Category GO:0046488 phosphatidylinositol metabolic process Database 0
Category members GO Category GO:0046813 receptor-mediated virion attachment to host cell Database 0
Category members GO Category GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation Database 0
Category members GO Category GO:0050776 regulation of immune response Database 0


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