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Query: JAM2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
JAM2 0 2.222 0.170 0.960

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
JAM2 Ubiquitylation K291 0.436 0.826 _ATTMSENDFK(gl)HTK_

Background Information for JAM2:


Pubmed-JAM2 »
Uniprot-JAM2 »
Biogrid-JAM2 »
ProteomicsDB-JAM2 »

Tumorportal-JAM2 »
COSMIC-JAM2 »
GenomeRNAi-JAM2 »
Genecards-JAM2


Protein-protein Interactions for JAM2
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in JAM2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ig-like_dom IPR007110 0.6
Category members Ig_sub IPR003599 0.43
Category members Immunoglobulin IPR013151 0.23
Category members Ig_sub2 IPR003598 0.21
Category members Ig_I-set IPR013098 0.13
Category members Ig_V-set IPR013106 0.09


Protein complexes (CORUM database) featuring JAM2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2422 ITGA4-ITGB1-JAM2 complex Database 0.25


Categories featuring JAM2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members Pathway Pathway_413 KEGG_TIGHT_JUNCTION 0 2.08
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0005923 tight junction Database 0.69
Category members Pathway Pathway_53 REACTOME_HEMOSTASIS 0 0.4
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members GO Category GO:0046982 protein heterodimerization activity Database 0.28
Category members Pathway Pathway_188 KEGG_EPITHELIAL_CELL_SIGNALING_IN_HELICOBACTER_PYLORI_INFECTION 0 0.24
Category members Pathway Pathway_957 PID_AMB2_NEUTROPHILS_PATHWAY 0 0.2
Category members Pathway Pathway_605 KEGG_LEUKOCYTE_TRANSENDOTHELIAL_MIGRATION 0 0.2
Category members Pathway Pathway_600 REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL 0 0.05
Category members GO Category GO:0050900 leukocyte migration Database 0.04
Category members Pathway Pathway_1024 PID_INTEGRIN_A4B1_PATHWAY 0 0
Category members Pathway Pathway_1027 PID_INTEGRIN1_PATHWAY 0 0
Category members Pathway Pathway_1217 KEGG_CELL_ADHESION_MOLECULES_CAMS 0 0
Category members Pathway Pathway_930 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS 0 0
Category members GO Category GO:0007162 negative regulation of cell adhesion Database 0
Category members GO Category GO:0016337 cell-cell adhesion Database 0


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