bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: YWHAZ

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
YWHAZ 0 4.221 0.880 -0.450 0.433 1.494 -0.337 0.631 0.064

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
YWHAZ Ubiquitylation K49 0.656 1.019 _NLLSVAYK(gl)NVVGAR_
YWHAZ Ubiquitylation K138 0.560 1.003 _YLAEVAAGDDK(gl)K_
YWHAZ Ubiquitylation K139 0.551 1.003 _YLAEVAAGDDKK(gl)_
YWHAZ Ubiquitylation K9 0.917 0.954 _(ac)MDKNELVQK(gl)AK_
YWHAZ Ubiquitylation K122 0.498 0.837 _MK(gl)GDYYR_
YWHAZ Ubiquitylation K3 0.268 0.388 _(ac)MDK(gl)NELVQK_
YWHAZ Ubiquitylation K11 0.016 0.388 _AK(gl)LAEQAERYDDMAACMK_
YWHAZ Ubiquitylation K166 -0.439 -0.371 _K(gl)EMQPTHPIR_
YWHAZ Ubiquitylation K68 0.504 _VVSSIEQK(gl)TEGAEK_
YWHAZ Ubiquitylation K74 0.762 _VVSSIEQKTEGAEK(gl)K_
YWHAZ Ubiquitylation K85 -0.089 _EK(gl)IETELR_

Background Information for YWHAZ:


Pubmed-YWHAZ »
Uniprot-YWHAZ »
Biogrid-YWHAZ »
ProteomicsDB-YWHAZ »

Tumorportal-YWHAZ »
COSMIC-YWHAZ »
GenomeRNAi-YWHAZ »
Genecards-YWHAZ


Protein-protein Interactions for YWHAZ
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDC25B Cat. description Hein, Mann, Cell 2015
Category members IP bait CENPE Cat. description Hein, Mann, Cell 2015
Category members IP bait MAP3K2 Cat. description Hein, Mann, Cell 2015
Category members IP bait YAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait YWHAH Cat. description Hein, Mann, Cell 2015
Category members IP bait YWHAZ Cat. description Hein, Mann, Cell 2015
Category members IP bait ABLIM1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ANKRD55 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BRAF Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C22orf33 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDC25A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDC25B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDCA7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CGN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CRTC2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EPB41L2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EPB49 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM163A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM189A2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM53C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIAA0748 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIAA0930 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MDM4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NKD2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PAK6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PAK7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLEKHG5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRICKLE3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAB11FIP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RALGPS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait REEP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RIN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SAMD4A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SAMD4B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SFN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SMTNL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPATA13 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SSH1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STAC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TFEB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF397 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in YWHAZ
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members 14/03/2003 IPR000308 1.96
Category members 14-3-3_domain IPR023410 1.96


Protein complexes (CORUM database) featuring YWHAZ
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5199 Kinase maturation complex 1 Database 3.38
Category members Corum 5919 BRAF-RAF1-14-3-3 complex Database 1.97


Categories featuring YWHAZ
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_771 REACTOME_METABOLISM_OF_RNA 0 INF
Category members Pathway Pathway_773 REACTOME_METABOLISM_OF_MRNA 0 INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0016070 RNA metabolic process Database INF
Category members GO Category GO:0016071 mRNA metabolic process Database INF
Category members DDR Literature pubmedid:TBD2_UV_increased Elia et al, 2015 UV increased acetylation events Elia et al. INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0042470 melanosome Database 5.59
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members Pathway Pathway_865 PID_ATR_PATHWAY 0 3.46
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members GO Category GO:0043234 protein complex Database 2.73
Category members Pathway Pathway_223 KEGG_OOCYTE_MEIOSIS 0 2.71
Category members GO Category GO:0031252 cell leading edge Database 2.52
Category members Pathway Pathway_934 PID_PI3KCI_AKT_PATHWAY 0 2.5
Category members Pathway Pathway_866 KEGG_CELL_CYCLE 0 2.13
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members Pathway Pathway_781 REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS 0 2.04
Category members Pathway Pathway_724 PID_MTOR_4PATHWAY 0 2
Category members Pathway Pathway_579 PID_ERBB1_DOWNSTREAM_PATHWAY 0 1.97
Category members GO Category GO:0019904 protein domain specific binding Database 1.85
Category members Pathway Pathway_636 PID_PI3K_PLC_TRK_PATHWAY 0 1.85
Category members Pathway Pathway_455 PID_INSULIN_GLUCOSE_PATHWAY 0 1.7
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members Pathway Pathway_1023 PID_NFAT_3PATHWAY 0 1.46
Category members GO Category GO:0070062 extracellular vesicular exosome Database 1.36
Category members Pathway Pathway_561 PID_PDGFRB_PATHWAY 0 1.18
Category members Pathway Pathway_118 PID_FOXO_PATHWAY 0 0.97
Category members Pathway Pathway_529 KEGG_NEUROTROPHIN_SIGNALING_PATHWAY 0 0.75
Category members GO Category GO:0042493 response to drug Database 0.66
Category members Pathway Pathway_509 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES 0 0.62
Category members GO Category GO:0030659 cytoplasmic vesicle membrane Database 0.62
Category members Pathway Pathway_123 BIOCARTA_CHREBP2_PATHWAY 0 0.61
Category members Pathway Pathway_1142 PID_LKB1_PATHWAY 0 0.6
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members Pathway Pathway_199 PID_BETA_CATENIN_NUC_PATHWAY 0 0.53
Category members GO Category GO:0032403 protein complex binding Database 0.49
Category members Pathway Pathway_1026 KEGG_PATHOGENIC_ESCHERICHIA_COLI_INFECTION 0 0.45
Category members Pathway Pathway_444 PID_P38_MK2_PATHWAY 0 0.42
Category members Pathway Pathway_53 REACTOME_HEMOSTASIS 0 0.4
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members Pathway Pathway_603 PID_IGF1_PATHWAY 0 0.39
Category members GO Category GO:0019901 protein kinase binding Database 0.37
Category members GO Category GO:0008134 transcription factor binding Database 0.37
Category members Pathway Pathway_505 REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM 0 0.33
Category members Pathway Pathway_408 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY 0 0.32
Category members GO Category GO:0006605 protein targeting Database 0.29
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members GO Category GO:0016301 kinase activity Database 0.23
Category members Pathway Pathway_165 SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES 0 0.18
Category members GO Category GO:0030168 platelet activation Database 0.13
Category members GO Category GO:0006626 protein targeting to mitochondrion Database 0.11
Category members Pathway Pathway_56 REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION 0 0.11
Category members Pathway Pathway_626 PID_A6B1_A6B4_INTEGRIN_PATHWAY 0 0.09
Category members GO Category GO:0002553 histamine secretion by mast cell Database 0.04
Category members Pathway Pathway_847 REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP 0 0.04
Category members Pathway Pathway_1152 REACTOME_RAP1_SIGNALLING 0 0.01
Category members Pathway Pathway_1024 PID_INTEGRIN_A4B1_PATHWAY 0 0
Category members Pathway Pathway_504 REACTOME_SIGNALING_BY_ILS 0 0
Category members Pathway Pathway_506 REACTOME_IL_3_5_AND_GM_CSF_SIGNALING 0 0
Category members Pathway Pathway_550 PID_IL3_PATHWAY 0 0
Category members Pathway Pathway_569 PID_GMCSF_PATHWAY 0 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0010941 regulation of cell death Database 0
Category members GO Category GO:0014069 postsynaptic density Database 0


.

© Copyright Svejstrup Laboratory 2015