RNAi screen result	RNAPII IP (MG132)	CSB IP	CSB IP (MG132)	Chrom.	Chrom. (MG132)	Ubi /Phospo	Ubi /Phospho (MG132)
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Gene name	MGoogle Score	RNAi high	RNAi low	RNAPII-IP (MG132)	CSB-IP	CSB-IP (MG132)	Chrom.	Chrom. (MG132)
RAF1	1	2.020	-1.230
KRAS	1	-0.510	0.620				1.031	0.887
KRAS	1	-0.510	0.620				0.246	-0.346
MAP2K1	1	-1.590	2.780
NRAS	1	1.810	-0.720				0.246	-0.346
LYN	1	-1.790	3.770
LYN	1	-1.790	3.770
PRKACA	0	0.380	-0.680		-1.005	-0.697	0.234	0.487
MAPK3	0
IKBKB	0	0.400	0.610
STAT1	0	-0.550	0.170
SOS1	0	0.500	-0.620	-0.570
PIK3CA	0
MAP2K2	0	-0.610	0.080
MAP2K2	0	-0.610	0.080
PRKACB	0	1.740	-1.200		-1.064
PRKACB	0	1.740	-1.200		-1.005	-0.697	0.234	0.487
PIK3R1	0	1.910	-1.220				-0.441	0.147
YWHAZ	0	0.880	-0.450	0.433	1.494	-0.337	0.631	0.064
STAT3	0	0.200	-1.270					0.334
STAT5B	0	0.670	-0.960
HRAS	0	1.470	-0.520
GRB2	0	-0.240	0.300		-1.021	0.057	0.906
PTPN11	0	-0.210	-0.400	0.644			1.053	0.451

Gene name	PTM type	PTM site	UV	UV (MG132)	Sequence
GRB2	Ubiquitylation	K10	0.146		_YDFK(gl)ATADDELSFK_
GRB2	Ubiquitylation	K20	-0.078		_ATADDELSFK(gl)R_
GRB2	Ubiquitylation	K69	-0.362	0.641	_AK(gl)AEEMLSK_
GRB2	Ubiquitylation	K76	0.754		_AEEMLSK(gl)QR_
GRB2	Ubiquitylation	K109	0.381	-0.002	_FGNDVQHFK(gl)VLR_
HRAS	Ubiquitylation	K170	-1.005		_K(gl)LNPPDESGPGCMSCK_
IKBKB	Ubiquitylation	K106	0.253		_K(gl)YLNQFENCCGLR_
IKBKB	Phosphorylation	S672	0.670	0.244	_GPVSGS(ph)PDSMNASR_
KRAS	Ubiquitylation	K128	1.528	1.433	_TVDTK(gl)QAHELAK_
KRAS	Ubiquitylation	K235	0.591	0.087	_TVDTK(gl)QAQDLAR_
KRAS	Ubiquitylation	K254	-0.450	-0.156	_SYGIPFIETSAK(gl)TR_
LYN	Ubiquitylation	K20	-0.592		_GKDSLSDDGVDLK(gl)TQPVR_
LYN	Ubiquitylation	K40	0.100		_DPTSNK(gl)QQRPVPESQLLPGQR_
LYN	Phosphorylation	S104	0.944	0.841	_DSLS(ph)DDGVDLK_
LYN	Ubiquitylation	K213	0.441		_HYQK(gl)QADGLCR_
LYN	Ubiquitylation	K477	-0.191		_VENCPDELYDIMK(gl)MCWK_
MAP2K1	Ubiquitylation	K192	-0.205	-0.241	_DVK(gl)PSNILVNSR_
MAP2K1	Phosphorylation	S385		0.066	_RSDAEEVDFAGWLCSTIGLNQPS(ph)TPTHAAGV_
MAP2K1	Phosphorylation	T386		0.377	_RSDAEEVDFAGWLCSTIGLNQPST(ph)PTHAAGV_
MAP2K2	Phosphorylation	S23	0.873	0.258	_RKPVLPALTINPTIAEGPS(ph)PTSEGASEANLVDLQK_
MAP2K2	Phosphorylation	T25		0.439	_RKPVLPALTINPTIAEGPSPT(ph)SEGASEANLVDLQK_
MAP2K2	Ubiquitylation	K192	-0.205	-0.241	_DVK(gl)PSNILVNSR_
MAP2K2	Phosphorylation	S293		-0.361	_ELEAIFGRPVVDGEEGEPHS(ph)ISPR_
MAP2K2	Phosphorylation	S295	-0.234	0.026	_ELEAIFGRPVVDGEEGEPHSIS(ph)PR_
MAP2K2	Phosphorylation	T394	0.570	0.158	_LNQPGT(ph)PTR_
MAPK3	Phosphorylation	Y204	-0.807	-2.487	_IADPEHDHTGFLTEY(ph)VATR_
MAPK3	Ubiquitylation	K289		-0.608	_NYLQSLPSKTK(gl)_
NRAS	Ubiquitylation	K128	1.528	1.433	_TVDTK(gl)QAHELAK_
PIK3CA	Ubiquitylation	K864	0.390	0.588	_NSHTIM(ox)QIQCK(gl)GGLK_
PIK3CA	Ubiquitylation	K868	0.204	0.651	_NSHTIM(ox)QIQCKGGLK(gl)_
PIK3CA	Ubiquitylation	K974	-0.273		_GAQECTK(gl)TREFER_
PRKACA	Ubiquitylation	K30	-0.143		_AKEDFLKK(gl)_
PRKACA	Ubiquitylation	K93	0.839	0.714	_QIEHTLNEK(gl)R_
PRKACB	Ubiquitylation	K30	-0.143		_AKEDFLKK(gl)_
PRKACB	Ubiquitylation	K93	0.839	0.714	_QIEHTLNEK(gl)R_
PRKACB	Phosphorylation	T243		-0.835	_T(ph)WTLCGTPEYLAPEIILSK_
PRKACB	Phosphorylation	T245	-0.116	-0.102	_TWT(ph)LCGTPEYLAPEIILSK_
PTPN11	Ubiquitylation	K124	0.562		_EAEK(gl)LLTEK_
RAF1	Phosphorylation	S29	0.028	-0.571	_DAVFDGSSCIS(ph)PTIVQQFGYQR_
RAF1	Phosphorylation	T31	0.028	-0.669	_DAVFDGSSCIS(ph)PTIVQQFGYQR_
RAF1	Phosphorylation	S244		0.053	_YSTPHAFTFNTSS(ph)PSSEGSLSQR_
RAF1	Phosphorylation	S259	-0.069	0.054	_STS(ph)TPNVHM(ox)VSTTLPVDSR_
RAF1	Phosphorylation	S301		-0.651	_SHSESASPSALSSSPNNLS(ph)PTGWSQPK_
RAF1	Phosphorylation	T303		-0.664	_SHSESASPSALSSSPNNLSPT(ph)GWSQPK_
RAF1	Phosphorylation	S497		-0.449	_SRWS(ph)GSQQVEQPTGSVLWMAPEVIR_
RAF1	Phosphorylation	S621	0.212	0.271	_SAS(ph)EPSLHR_
RAF1	Phosphorylation	S642	-0.197	0.463	_AAHTEDINACTLTTS(ph)PR_
SOS1	Phosphorylation	S1082	0.278		_IPESETESTASAPNS(ph)PR_
SOS1	Phosphorylation	S1166	0.097	-0.094	_RPESAPAES(ph)SPSK_
STAT1	Phosphorylation	S727	1.377	0.974	_LQTTDNLLPMS(ph)PEEFDEVSR_
STAT3	Ubiquitylation	K177	0.957		_VVENLQDDFDFNYK(gl)TLK_
STAT3	Ubiquitylation	K180	1.179		_TLK(gl)SQGDMQDLNGNNQSVTR_
STAT3	Ubiquitylation	K244	0.262		_TLTDEELADWK(gl)R_
STAT3	Phosphorylation	T714		-0.338	_FICVT(ph)PTTCSNTIDLPMS(ph)PR_
STAT3	Phosphorylation	S727	-0.079	0.156	_FICVTPTTCSNTIDLPMS(ph)PR_
STAT5B	Phosphorylation	S194		0.270	_IQAQFGPLAQLS(ph)PQER_
YWHAZ	Ubiquitylation	K3	0.268	0.388	_(ac)MDK(gl)NELVQK_
YWHAZ	Ubiquitylation	K9	0.917	0.954	_(ac)MDKNELVQK(gl)AK_
YWHAZ	Ubiquitylation	K11	0.016	0.388	_AK(gl)LAEQAERYDDMAACMK_
YWHAZ	Ubiquitylation	K49	0.656	1.019	_NLLSVAYK(gl)NVVGAR_
YWHAZ	Ubiquitylation	K68	0.504		_VVSSIEQK(gl)TEGAEK_
YWHAZ	Ubiquitylation	K74	0.762		_VVSSIEQKTEGAEK(gl)K_
YWHAZ	Ubiquitylation	K85	-0.089		_EK(gl)IETELR_
YWHAZ	Ubiquitylation	K122	0.498	0.837	_MK(gl)GDYYR_
YWHAZ	Ubiquitylation	K138	0.560	1.003	_YLAEVAAGDDK(gl)K_
YWHAZ	Ubiquitylation	K139	0.551	1.003	_YLAEVAAGDDKK(gl)_
YWHAZ	Ubiquitylation	K166	-0.439	-0.371	_K(gl)EMQPTHPIR_