RNAi screen result	RNAPII IP (MG132)	CSB IP	CSB IP (MG132)	Chrom.	Chrom. (MG132)	Ubi /Phospo	Ubi /Phospho (MG132)
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Gene name	MGoogle Score	RNAi high	RNAi low	RNAPII-IP (MG132)	CSB-IP	CSB-IP (MG132)	Chrom.	Chrom. (MG132)
TAB3	2	-0.550	1.560				0.022	-0.207
TAB3	2	-0.550	1.560
FYN	1	1.080	-1.100
FYN	1	1.080	-1.100
CUL1	1	0.630	-0.610	-0.314	0.662	2.069	0.342	0.118
TAB1	1	1.890	-0.670
TAB1	1	1.890	-0.670	1.657
RIPK2	1	-1.740	3.580
PIK3R2	1	2.740	-1.180				0.269	0.348
RAF1	1	2.020	-1.230
KRAS	1	-0.510	0.620				1.031	0.887
KRAS	1	-0.510	0.620				0.246	-0.346
PELI2	1	-0.150	0.600
MAP2K1	1	-1.590	2.780
PELI1	1	-0.190	-0.210
NRAS	1	1.810	-0.720				0.246	-0.346
LYN	1	-1.790	3.770
LYN	1	-1.790	3.770
PIK3CB	0	-1.390	2.350
PIK3CB	0	-0.710	1.450
TAB2	0	-0.030	-0.580
MAP2K4	0	-0.300	0.320
NFKB2	0	1.750	-0.820
TOLLIP	0	-0.050	0.340	-0.613
TOLLIP	0	0.160	-0.150	-0.613
CRKL	0	0.290	-0.620
RBX1	0	0.920	-0.940	-0.015			-0.422
MAPK3	0
IKBKB	0	0.400	0.610
RAPGEF1	0	1.620	-0.780
MAP2K6	0	1.270	-0.780
SKP1	0	1.470	-0.970		-1.305	-0.243	-0.093	0.054
SKP1	0	1.470	-0.970	-0.472
STAT1	0	-0.550	0.170
SOS1	0	0.500	-0.620	-0.570
PIK3R3	0	-0.140	-0.480
PIK3R3	0	-0.140	-0.480				-0.441	0.147
PIK3CA	0
TMEM189-UB	0
TMEM189-UB	0
MAP2K2	0	-0.610	0.080
MAP2K2	0	-0.610	0.080
MAP3K7	0	-1.120	1.140	-1.048
IL1RN	0	-0.390	0.260					-3.729
PRKACB	0	1.740	-1.200		-1.064
PRKACB	0	1.740	-1.200		-1.005	-0.697	0.234	0.487
PIK3R1	0	1.910	-1.220				-0.441	0.147
SQSTM1	0	-0.860	1.770	-2.165			-2.063	-1.741
SQSTM1	0	-0.440	0.530	-2.165			-2.063	-1.741
JAK1	0	0.190	-0.100		-1.504	-0.381		-0.438
YWHAZ	0	0.880	-0.450	0.433	1.494	-0.337	0.631	0.064
INPPL1	0	1.690	-0.810
BTRC	0	-0.780	0.690	0.532			-1.791	0.313
YWHAB	0				0.628	-0.543
YWHAB	0			0.507			0.271	0.503
CRK	0	-0.790	0.230
STAT3	0	0.200	-1.270					0.334
CDK1	0	-0.370	0.080	-0.202	-0.884	-0.107	-0.097	-0.501
RELA	0	-1.130	1.600	0.793
STAT5B	0	0.670	-0.960
HRAS	0	1.470	-0.520
YES1	0	0.340	-0.470				0.295	0.576
GRB2	0	-0.240	0.300		-1.021	0.057	0.906
LCK	0	-0.490	1.390				0.295	0.576
MAP3K3	0	0.830	-0.050
CHUK	0			-0.480

Gene name	PTM type	PTM site	UV	UV (MG132)	Sequence
BTRC	Ubiquitylation	K466		0.325	_IVSGAYDGKIK(gl)_
CDK1	Ubiquitylation	K6	0.011	-0.784	_(ac)M(ox)EDYTK(gl)IEK_
CDK1	Ubiquitylation	K20	-0.327	-0.270	_IGEGTYGVVYK(gl)GR_
CDK1	Ubiquitylation	K33	0.736	0.239	_TTGQVVAMK(gl)K_
CDK1	Ubiquitylation	K34		-0.306	_TTGQVVAMKK(gl)_
CDK1	Ubiquitylation	K58	0.312	-0.262	_EISLLK(gl)ELR_
CDK1	Ubiquitylation	K136		-0.468	_DLK(gl)PQNLLIDDK(gl)GTIK_
CDK1	Ubiquitylation	K145	0.161	-0.954	_DLKPQNLLIDDK(gl)GTIK_
CDK1	Ubiquitylation	K149		-0.038	_GTIK(gl)LADFGLAR_
CDK1	Ubiquitylation	K251	-0.047	-1.236	_WK(gl)PGSLASHVK_
CDK1	Ubiquitylation	K280	0.179	-1.210	_MLIYDPAK(gl)R_
CHUK	Ubiquitylation	K296		-1.637	_GGPVDLTLK(gl)QPR_
CRK	Phosphorylation	S40	0.533	0.363	_DS(ph)STSPGDYVLSVSENSR_
CRK	Phosphorylation	S41	1.065	0.801	_DSS(ph)TSPGDYVLSVSENSR_
CRKL	Phosphorylation	S41		0.868	_DS(ph)STCPGDYVLSVSENSR_
CRKL	Phosphorylation	S107	-0.818	-1.177	_YPS(ph)PPMGSVSAPNLPTAEDNLEYVR_
CUL1	Ubiquitylation	K262	0.119		_ESTEFLQQNPVTEYMK(gl)K_
CUL1	Ubiquitylation	K263	0.119	-0.055	_ESTEFLQQNPVTEYMK(gl)K_
CUL1	Ubiquitylation	K410	0.250	0.326	_FINNNAVTK(gl)MAQSSSK_
CUL1	Ubiquitylation	K417		0.761	_MAQSSSK(gl)SPELLAR_
CUL1	Ubiquitylation	K468	1.237		_FYAK(gl)MLAK_
CUL1	Ubiquitylation	K503		0.665	_QACGFEYTSK(gl)LQR_
CUL1	Ubiquitylation	K769	0.292		_VDGEK(gl)DTYSYLA_
FYN	Ubiquitylation	K13	0.286		_DKEATK(gl)LTEER_
FYN	Phosphorylation	S21	0.373	0.731	_DGS(ph)LNQSSGYR_
FYN	Ubiquitylation	K259		0.921	_LTDLSVK(gl)TK_
FYN	Ubiquitylation	K261	0.099		_LTDLSVKTK(gl)_
FYN	Ubiquitylation	K273	6.025		_SLCLEKK(gl)_
FYN	Ubiquitylation	K275	-0.521		_ESLQLIK(gl)R_
GRB2	Ubiquitylation	K10	0.146		_YDFK(gl)ATADDELSFK_
GRB2	Ubiquitylation	K20	-0.078		_ATADDELSFK(gl)R_
GRB2	Ubiquitylation	K69	-0.362	0.641	_AK(gl)AEEMLSK_
GRB2	Ubiquitylation	K76	0.754		_AEEMLSK(gl)QR_
GRB2	Ubiquitylation	K109	0.381	-0.002	_FGNDVQHFK(gl)VLR_
HRAS	Ubiquitylation	K170	-1.005		_K(gl)LNPPDESGPGCMSCK_
IKBKB	Ubiquitylation	K106	0.253		_K(gl)YLNQFENCCGLR_
IKBKB	Phosphorylation	S672	0.670	0.244	_GPVSGS(ph)PDSMNASR_
INPPL1	Phosphorylation	S1003	-1.290		_NSFNNPAYYVLEGVPHQLLPPEPPS(ph)PAR_
JAK1	Ubiquitylation	K227	-0.405		_YIPETLNK(gl)SIR_
JAK1	Ubiquitylation	K249	0.116	0.771	_DFLK(gl)EFNNK_
JAK1	Ubiquitylation	K559	-0.478		_EISNLLVATK(gl)K_
KRAS	Ubiquitylation	K128	1.528	1.433	_TVDTK(gl)QAHELAK_
KRAS	Ubiquitylation	K235	0.591	0.087	_TVDTK(gl)QAQDLAR_
KRAS	Ubiquitylation	K254	-0.450	-0.156	_SYGIPFIETSAK(gl)TR_
LCK	Phosphorylation	T37		-0.435	_YRPENTPEPVSTSVSHYGAEPT(ph)TVSPCPSSSAK_
LCK	Ubiquitylation	K191	-0.112	0.264	_ESETTK(gl)GAYSLSIR_
LCK	Ubiquitylation	K235	0.323		_AQFDTLQK(gl)LVK_
LCK	Ubiquitylation	K259		-1.613	_LTTVCPTVK(gl)PQTQGLAK_
LYN	Ubiquitylation	K20	-0.592		_GKDSLSDDGVDLK(gl)TQPVR_
LYN	Ubiquitylation	K40	0.100		_DPTSNK(gl)QQRPVPESQLLPGQR_
LYN	Phosphorylation	S104	0.944	0.841	_DSLS(ph)DDGVDLK_
LYN	Ubiquitylation	K213	0.441		_HYQK(gl)QADGLCR_
LYN	Ubiquitylation	K477	-0.191		_VENCPDELYDIMK(gl)MCWK_
MAP2K1	Ubiquitylation	K192	-0.205	-0.241	_DVK(gl)PSNILVNSR_
MAP2K1	Phosphorylation	S385		0.066	_RSDAEEVDFAGWLCSTIGLNQPS(ph)TPTHAAGV_
MAP2K1	Phosphorylation	T386		0.377	_RSDAEEVDFAGWLCSTIGLNQPST(ph)PTHAAGV_
MAP2K2	Phosphorylation	S23	0.873	0.258	_RKPVLPALTINPTIAEGPS(ph)PTSEGASEANLVDLQK_
MAP2K2	Phosphorylation	T25		0.439	_RKPVLPALTINPTIAEGPSPT(ph)SEGASEANLVDLQK_
MAP2K2	Ubiquitylation	K192	-0.205	-0.241	_DVK(gl)PSNILVNSR_
MAP2K2	Phosphorylation	S293		-0.361	_ELEAIFGRPVVDGEEGEPHS(ph)ISPR_
MAP2K2	Phosphorylation	S295	-0.234	0.026	_ELEAIFGRPVVDGEEGEPHSIS(ph)PR_
MAP2K2	Phosphorylation	T394	0.570	0.158	_LNQPGT(ph)PTR_
MAP2K4	Phosphorylation	S80		0.441	_LRTHS(ph)IESSGK_
MAP2K6	Phosphorylation	T28	-1.813	-0.792	_EAFEQPQTSST(ph)PPRDLDSK_
MAP2K6	Ubiquitylation	K232		0.220	_INPELNQK(gl)GYSVK_
MAP3K3	Phosphorylation	S166		-0.325	_HLS(ph)VSSQNPGR_
MAP3K3	Phosphorylation	S175	0.120	-0.091	_S(ph)SPPPGYVPER_
MAP3K3	Phosphorylation	S176	0.120	-0.091	_S(ph)SPPPGYVPER_
MAP3K3	Phosphorylation	S250	-0.070		_AQS(ph)FPDNR_
MAP3K7	Phosphorylation	S374	0.149	-0.337	_GS(ph)SVESLPPTSEGK_
MAP3K7	Phosphorylation	S375	0.171	-0.087	_GSS(ph)VESLPPTSEGK_
MAP3K7	Phosphorylation	S389	1.072	1.445	_RMS(ph)ADMSEIEAR_
MAP3K7	Phosphorylation	S439	0.246	0.198	_S(ph)IQDLTVTGTEPGQVSSR_
MAP3K7	Ubiquitylation	K474	-0.385	-0.242	_MITTSGPTSEK(gl)PTR_
MAP3K7	Ubiquitylation	K589	-0.104		_SLSTYYQQCK(gl)K_
MAP3K7	Ubiquitylation	K590	-0.551	0.560	_K(gl)QLEVIR_
MAPK3	Phosphorylation	Y204	-0.807	-2.487	_IADPEHDHTGFLTEY(ph)VATR_
MAPK3	Ubiquitylation	K289		-0.608	_NYLQSLPSKTK(gl)_
NFKB2	Ubiquitylation	K741		-2.393	_GHTPLDLTCSTK(gl)VK_
NFKB2	Ubiquitylation	K743	-0.624		_GHTPLDLTCSTKVK(gl)_
NRAS	Ubiquitylation	K128	1.528	1.433	_TVDTK(gl)QAHELAK_
PELI1	Ubiquitylation	K12	-0.817		_(ac)MFSPDQENHPSK(gl)APVK_
PELI1	Ubiquitylation	K172	1.788	0.291	_NIFLGEKAAK(gl)_
PELI2	Ubiquitylation	K172	1.788	0.291	_NIFLGEKAAK(gl)_
PIK3CA	Ubiquitylation	K864	0.390	0.588	_NSHTIM(ox)QIQCK(gl)GGLK_
PIK3CA	Ubiquitylation	K868	0.204	0.651	_NSHTIM(ox)QIQCKGGLK(gl)_
PIK3CA	Ubiquitylation	K974	-0.273		_GAQECTK(gl)TREFER_
PIK3CB	Ubiquitylation	K1044		0.990	_SEEEALKQFKQK(gl)_
PIK3R2	Phosphorylation	S262		-2.237	_APPPPS(ph)SPPPGGAPDGSEPSPDFPALLVEK_
PIK3R2	Phosphorylation	S263		-2.237	_APPPPS(ph)SPPPGGAPDGSEPSPDFPALLVEK_
PIK3R2	Ubiquitylation	K500	-0.189		_IFEEQGQTQEK(gl)CSK_
PIK3R2	Ubiquitylation	K541	-0.609		_TK(gl)LEQQLR_
PIK3R2	Ubiquitylation	K564	-0.431	-1.022	_MNSLK(gl)PDLMQLR_
PIK3R3	Ubiquitylation	K226		-0.376	_YQQDQLVKEDNIDAVGKK(gl)_
PIK3R3	Ubiquitylation	K320		0.385	_LGEIHDSK(gl)MR_
PRKACB	Ubiquitylation	K30	-0.143		_AKEDFLKK(gl)_
PRKACB	Ubiquitylation	K93	0.839	0.714	_QIEHTLNEK(gl)R_
PRKACB	Phosphorylation	T243		-0.835	_T(ph)WTLCGTPEYLAPEIILSK_
PRKACB	Phosphorylation	T245	-0.116	-0.102	_TWT(ph)LCGTPEYLAPEIILSK_
RAF1	Phosphorylation	S29	0.028	-0.571	_DAVFDGSSCIS(ph)PTIVQQFGYQR_
RAF1	Phosphorylation	T31	0.028	-0.669	_DAVFDGSSCIS(ph)PTIVQQFGYQR_
RAF1	Phosphorylation	S244		0.053	_YSTPHAFTFNTSS(ph)PSSEGSLSQR_
RAF1	Phosphorylation	S259	-0.069	0.054	_STS(ph)TPNVHM(ox)VSTTLPVDSR_
RAF1	Phosphorylation	S301		-0.651	_SHSESASPSALSSSPNNLS(ph)PTGWSQPK_
RAF1	Phosphorylation	T303		-0.664	_SHSESASPSALSSSPNNLSPT(ph)GWSQPK_
RAF1	Phosphorylation	S497		-0.449	_SRWS(ph)GSQQVEQPTGSVLWMAPEVIR_
RAF1	Phosphorylation	S621	0.212	0.271	_SAS(ph)EPSLHR_
RAF1	Phosphorylation	S642	-0.197	0.463	_AAHTEDINACTLTTS(ph)PR_
RAPGEF1	Phosphorylation	S377		0.629	_LSKS(ph)DEQLSSLDR_
RBX1	Phosphorylation	T9		-0.553	_(ac)AAAMDVDT(ph)PSGTNSGAGK_
RBX1	Ubiquitylation	K19	-0.376	-0.371	_(ac)AAAMDVDTPSGTNSGAGK(gl)KR_
RBX1	Ubiquitylation	K20	-0.541	-0.371	_(ac)AAAMDVDTPSGTNSGAGKK(gl)R_
RIPK2	Ubiquitylation	K410	-2.810		_AAFCDHK(gl)TTPCSSAIINPLSTAGNSER_
RIPK2	Phosphorylation	S531	0.884	0.839	_SPS(ph)LNLLQNK_
RIPK2	Ubiquitylation	K538	-2.659		_SPSLNLLQNK(gl)SM_
SKP1	Ubiquitylation	K130	0.138	0.140	_GK(gl)TPEEIRK_
SKP1	Phosphorylation	T131	-0.024	-0.138	_GKT(ph)PEEIRK_
SKP1	Ubiquitylation	K142	0.165	0.894	_TFNIK(gl)NDFTEEEEAQVRK_
SKP1	Ubiquitylation	K155	-0.096	0.069	_K(gl)ENQWCEEK_
SKP1	Ubiquitylation	K163	0.109	-0.020	_ENQWCEEK(gl)_
SOS1	Phosphorylation	S1082	0.278		_IPESETESTASAPNS(ph)PR_
SOS1	Phosphorylation	S1166	0.097	-0.094	_RPESAPAES(ph)SPSK_
SQSTM1	Ubiquitylation	K13	0.150	0.302	_AYLLGK(gl)EDAAR_
SQSTM1	Phosphorylation	S28		-0.721	_RFSFCCS(ph)PEPEAEAEAAAGPGPCER_
SQSTM1	Ubiquitylation	K141	-0.915		_YK(gl)CSVCPDYDLCSVCEGK_
SQSTM1	Ubiquitylation	K157	-0.852	-0.677	_CSVCPDYDLCSVCEGK(gl)GLHR_
SQSTM1	Phosphorylation	T269	-0.681	-0.421	_LT(ph)PVS(ph)PESSSTEEK_
SQSTM1	Phosphorylation	S272	0.171	0.044	_LTPVS(ph)PESSSTEEK_
SQSTM1	Phosphorylation	S332		-0.007	_IALESEGRPEEQMESDNCS(ph)GGDDDWTHLSSK_
SQSTM1	Ubiquitylation	K420	-1.122	-0.061	_LLQTK(gl)NYDIGAALDTIQYSK_
SQSTM1	Ubiquitylation	K435	-1.352	-0.780	_NYDIGAALDTIQYSK(gl)HPPPL_
STAT1	Phosphorylation	S727	1.377	0.974	_LQTTDNLLPMS(ph)PEEFDEVSR_
STAT3	Ubiquitylation	K177	0.957		_VVENLQDDFDFNYK(gl)TLK_
STAT3	Ubiquitylation	K180	1.179		_TLK(gl)SQGDMQDLNGNNQSVTR_
STAT3	Ubiquitylation	K244	0.262		_TLTDEELADWK(gl)R_
STAT3	Phosphorylation	T714		-0.338	_FICVT(ph)PTTCSNTIDLPMS(ph)PR_
STAT3	Phosphorylation	S727	-0.079	0.156	_FICVTPTTCSNTIDLPMS(ph)PR_
STAT5B	Phosphorylation	S194		0.270	_IQAQFGPLAQLS(ph)PQER_
TAB1	Phosphorylation	S7	-0.170	0.140	_S(ph)LLQSEQQPSWTDDLPLCHLSGVGSASNR_
TAB1	Phosphorylation	S16	-0.138	0.069	_SLLQSEQQPS(ph)WTDDLPLCHLSGVGSASNR_
TAB1	Ubiquitylation	K186	-1.015		_SYSADGK(gl)GTESHPPEDSWLK_
TAB1	Ubiquitylation	K371	0.032		_LSQLGLDAGK(gl)IK_
TAB1	Ubiquitylation	K373		-0.007	_LSQLGLDAGKIK(gl)_
TAB2	Phosphorylation	S580		-0.075	_S(ph)NSISQIPSLEEMQQLR_
TAB2	Phosphorylation	S582		0.331	_SNS(ph)ISQIPSLEEMQQLR_
TAB2	Ubiquitylation	K653	-0.519	-0.200	_SIIK(gl)TPK_
TAB3	Phosphorylation	S4	3.009	1.852	_(ac)AQS(ph)SPQLDIQVLHDLR_
TAB3	Phosphorylation	S5	3.009	1.852	_(ac)AQS(ph)SPQLDIQVLHDLR_
TMEM189-UBE2V1	Ubiquitylation	K42	-0.791	0.215	_ELAALYSPGK(gl)R_
TMEM189-UBE2V1	Ubiquitylation	K129	0.440	0.709	_LMMSK(gl)ENMK_
TMEM189-UBE2V1	Ubiquitylation	K291	-0.071	0.214	_IYSLK(gl)IECGPK_
TOLLIP	Ubiquitylation	K94	-0.411	0.859	_LNITVVQAK(gl)_
TOLLIP	Ubiquitylation	K97		0.276	_LAK(gl)NYGMTR_
TOLLIP	Ubiquitylation	K177	0.510		_QGK(gl)VEDKWYSLSGR_
YES1	Phosphorylation	T37		-0.435	_YRPENTPEPVSTSVSHYGAEPT(ph)TVSPCPSSSAK_
YES1	Ubiquitylation	K191	-0.112	0.264	_ESETTK(gl)GAYSLSIR_
YES1	Ubiquitylation	K235	0.323		_AQFDTLQK(gl)LVK_
YES1	Ubiquitylation	K259		-1.613	_LTTVCPTVK(gl)PQTQGLAK_
YWHAB	Ubiquitylation	K11	1.057	1.322	_(ac)TMDKSELVQK(gl)AK_
YWHAB	Ubiquitylation	K13	0.060	0.388	_AK(gl)LAEQAER_
YWHAB	Ubiquitylation	K70	0.558	-0.175	_VISSIEQK(gl)TER_
YWHAB	Ubiquitylation	K140		0.531	_YLSEVASGDNK(gl)QTTVSNSQQAYQEAFEISKK_
YWHAB	Ubiquitylation	K159	0.300		_QTTVSNSQQAYQEAFEISK(gl)K_
YWHAB	Ubiquitylation	K160	-0.439	-0.371	_K(gl)EMQPTHPIR_
YWHAZ	Ubiquitylation	K3	0.268	0.388	_(ac)MDK(gl)NELVQK_
YWHAZ	Ubiquitylation	K9	0.917	0.954	_(ac)MDKNELVQK(gl)AK_
YWHAZ	Ubiquitylation	K11	0.016	0.388	_AK(gl)LAEQAERYDDMAACMK_
YWHAZ	Ubiquitylation	K49	0.656	1.019	_NLLSVAYK(gl)NVVGAR_
YWHAZ	Ubiquitylation	K68	0.504		_VVSSIEQK(gl)TEGAEK_
YWHAZ	Ubiquitylation	K74	0.762		_VVSSIEQKTEGAEK(gl)K_
YWHAZ	Ubiquitylation	K85	-0.089		_EK(gl)IETELR_
YWHAZ	Ubiquitylation	K122	0.498	0.837	_MK(gl)GDYYR_
YWHAZ	Ubiquitylation	K138	0.560	1.003	_YLAEVAAGDDK(gl)K_
YWHAZ	Ubiquitylation	K139	0.551	1.003	_YLAEVAAGDDKK(gl)_
YWHAZ	Ubiquitylation	K166	-0.439	-0.371	_K(gl)EMQPTHPIR_