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Query: IL1RN

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
IL1RN 0 -3.469 -0.390 0.260 -3.729

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for IL1RN:


Pubmed-IL1RN »
Uniprot-IL1RN »
Biogrid-IL1RN »
ProteomicsDB-IL1RN »

Tumorportal-IL1RN »
COSMIC-IL1RN »
GenomeRNAi-IL1RN »
Genecards-IL1RN


Protein-protein Interactions for IL1RN
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDK15 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FCF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FTH1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SEC22C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TBC1D22B Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in IL1RN
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Cytokine_IL1-like IPR008996 0.02
Category members IL-1_fam IPR000975 0
Category members IL-1RA/IL-36 IPR003297 0


Protein complexes (CORUM database) featuring IL1RN
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring IL1RN
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005576 extracellular region Database 10.9
Category members GO Category GO:0005615 extracellular space Database 4.72
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members GO Category GO:0006955 immune response Database 1.22
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0030336 negative regulation of cell migration Database 0.85
Category members GO Category GO:0005813 centrosome Database 0.75
Category members GO Category GO:0042493 response to drug Database 0.66
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members Pathway Pathway_975 REACTOME_IL1_SIGNALING 0 0.42
Category members GO Category GO:0032496 response to lipopolysaccharide Database 0.35
Category members Pathway Pathway_505 REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM 0 0.33
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0007565 female pregnancy Database 0.19
Category members GO Category GO:0005152 interleukin-1 receptor antagonist activity Database 0.1
Category members GO Category GO:0051384 response to glucocorticoid Database 0.04
Category members GO Category GO:0014050 negative regulation of glutamate secretion Database 0.03
Category members GO Category GO:0010243 response to organonitrogen compound Database 0.02
Category members GO Category GO:0031982 vesicle Database 0.01
Category members Pathway Pathway_1054 BIOCARTA_IL1R_PATHWAY 0 0
Category members Pathway Pathway_504 REACTOME_SIGNALING_BY_ILS 0 0
Category members Pathway Pathway_631 PID_IL1_PATHWAY 0 0
Category members GO Category GO:0001660 fever generation Database 0
Category members GO Category GO:0001960 negative regulation of cytokine-mediated signaling pathway Database 0
Category members GO Category GO:0002439 chronic inflammatory response to antigenic stimulus Database 0
Category members GO Category GO:0005149 interleukin-1 receptor binding Database 0
Category members GO Category GO:0005150 interleukin-1, Type I receptor binding Database 0
Category members GO Category GO:0006629 lipid metabolic process Database 0
Category members GO Category GO:0006953 acute-phase response Database 0
Category members GO Category GO:0007613 memory Database 0
Category members GO Category GO:0014070 response to organic cyclic compound Database 0
Category members GO Category GO:0019752 carboxylic acid metabolic process Database 0
Category members GO Category GO:0030073 insulin secretion Database 0
Category members GO Category GO:0034115 negative regulation of heterotypic cell-cell adhesion Database 0
Category members GO Category GO:0043507 positive regulation of JUN kinase activity Database 0
Category members GO Category GO:0045837 negative regulation of membrane potential Database 0
Category members GO Category GO:0070670 response to interleukin-4 Database 0


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