Results for the Category
BIOCARTA_IL1R_PATHWAY
(Pathway_1054)
RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
W | |||||||
Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
---|---|---|---|---|---|---|---|---|
JUN | 3 | -0.930 | 0.930 | -0.126 | ||||
MAPK14 | 2 | -0.160 | -0.350 | |||||
TAB1 | 1 | 1.890 | -0.670 | |||||
TAB1 | 1 | 1.890 | -0.670 | 1.657 | ||||
MAP2K3 | 0 | 0.780 | -0.600 | |||||
TOLLIP | 0 | -0.050 | 0.340 | -0.613 | ||||
TOLLIP | 0 | 0.160 | -0.150 | -0.613 | ||||
MAP3K1 | 0 | 0.750 | -1.270 | |||||
IKBKB | 0 | 0.400 | 0.610 | |||||
TGFB1 | 0 | -0.550 | 1.050 | |||||
MAP2K6 | 0 | 1.270 | -0.780 | |||||
NFKB1 | 0 | 0.720 | -0.810 | |||||
TGFB3 | 0 | 0.900 | -0.540 | |||||
ECSIT | 0 | 0.240 | -1.150 | -1.026 | -0.458 | |||
MAP3K7 | 0 | -1.120 | 1.140 | -1.048 | ||||
IL1RN | 0 | -0.390 | 0.260 | -3.729 | ||||
RELA | 0 | -1.130 | 1.600 | 0.793 | ||||
CHUK | 0 | -0.480 |
Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
---|---|---|---|---|---|
CHUK | Ubiquitylation | K296 | -1.637 | _GGPVDLTLK(gl)QPR_ | |
IKBKB | Ubiquitylation | K106 | 0.253 | _K(gl)YLNQFENCCGLR_ | |
IKBKB | Phosphorylation | S672 | 0.670 | 0.244 | _GPVSGS(ph)PDSMNASR_ |
JUN | Phosphorylation | S58 | -0.167 | -1.247 | _AKNS(ph)DLLTSPDVGLLK_ |
JUN | Phosphorylation | T62 | 2.545 | 1.674 | _NSDLLT(ph)SPDVGLLK_ |
JUN | Phosphorylation | S63 | 2.030 | 1.458 | _NSDLLTS(ph)PDVGLLK_ |
JUN | Ubiquitylation | K70 | 9.213 | _NSDLLTSPDVGLLK(gl)_ | |
JUN | Phosphorylation | S73 | 1.499 | 0.845 | _LAS(ph)PELER_ |
JUN | Phosphorylation | S243 | -0.642 | -1.399 | _LQALKEEPQTVPEMPGETPPLS(ph)PIDMESQER_ |
JUN | Ubiquitylation | K309 | 1.034 | 0.155 | _EQVAQLK(gl)QK_ |
MAP2K3 | Ubiquitylation | K84 | 0.045 | -0.277 | _GAYGVVEK(gl)VR_ |
MAP2K3 | Ubiquitylation | K232 | -1.394 | _TMDAGCK(gl)PYMAPER_ | |
MAP2K3 | Ubiquitylation | K247 | 0.065 | -0.737 | _INPELNQK(gl)GYNVK_ |
MAP2K6 | Phosphorylation | T28 | -1.813 | -0.792 | _EAFEQPQTSST(ph)PPRDLDSK_ |
MAP2K6 | Ubiquitylation | K232 | 0.220 | _INPELNQK(gl)GYSVK_ | |
MAP3K1 | Phosphorylation | S292 | 0.209 | _RAPS(ph)PDGFSPYSPEETNR_ | |
MAP3K1 | Phosphorylation | S506 | 1.427 | _SHDFYSHELS(ph)SPVDSPSSLR_ | |
MAP3K1 | Phosphorylation | S507 | 1.436 | _SHDFYSHELSS(ph)PVDSPSSLR_ | |
MAP3K1 | Phosphorylation | S923 | 0.127 | -0.120 | _LSAS(ph)SEDISER_ |
MAP3K7 | Phosphorylation | S374 | 0.149 | -0.337 | _GS(ph)SVESLPPTSEGK_ |
MAP3K7 | Phosphorylation | S375 | 0.171 | -0.087 | _GSS(ph)VESLPPTSEGK_ |
MAP3K7 | Phosphorylation | S389 | 1.072 | 1.445 | _RMS(ph)ADMSEIEAR_ |
MAP3K7 | Phosphorylation | S439 | 0.246 | 0.198 | _S(ph)IQDLTVTGTEPGQVSSR_ |
MAP3K7 | Ubiquitylation | K474 | -0.385 | -0.242 | _MITTSGPTSEK(gl)PTR_ |
MAP3K7 | Ubiquitylation | K589 | -0.104 | _SLSTYYQQCK(gl)K_ | |
MAP3K7 | Ubiquitylation | K590 | -0.551 | 0.560 | _K(gl)QLEVIR_ |
MAPK14 | Phosphorylation | S2 | 3.221 | 3.623 | _(ac)S(ph)QERPTFYR_ |
MAPK14 | Phosphorylation | T180 | 0.958 | 1.087 | _HTDDEM(ox)T(ph)GYVATR_ |
MAPK14 | Phosphorylation | Y182 | 1.388 | 1.374 | _HTDDEM(ox)TGY(ph)VATR_ |
MAPK14 | Ubiquitylation | K249 | 0.073 | -1.380 | _LVGTPGAELLKK(gl)_ |
NFKB1 | Phosphorylation | S907 | -0.025 | 0.113 | _TTSQAHSLPLS(ph)PASTR_ |
TAB1 | Phosphorylation | S7 | -0.170 | 0.140 | _S(ph)LLQSEQQPSWTDDLPLCHLSGVGSASNR_ |
TAB1 | Phosphorylation | S16 | -0.138 | 0.069 | _SLLQSEQQPS(ph)WTDDLPLCHLSGVGSASNR_ |
TAB1 | Ubiquitylation | K186 | -1.015 | _SYSADGK(gl)GTESHPPEDSWLK_ | |
TAB1 | Ubiquitylation | K371 | 0.032 | _LSQLGLDAGK(gl)IK_ | |
TAB1 | Ubiquitylation | K373 | -0.007 | _LSQLGLDAGKIK(gl)_ | |
TGFB1 | Ubiquitylation | K50 | -0.557 | _GQILSK(gl)LR_ | |
TGFB3 | Ubiquitylation | K50 | -0.557 | _GQILSK(gl)LR_ | |
TOLLIP | Ubiquitylation | K94 | -0.411 | 0.859 | _LNITVVQAK(gl)_ |
TOLLIP | Ubiquitylation | K97 | 0.276 | _LAK(gl)NYGMTR_ | |
TOLLIP | Ubiquitylation | K177 | 0.510 | _QGK(gl)VEDKWYSLSGR_ |
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