bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: TOLLIP

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TOLLIP 0 1.095 -0.050 0.340 -0.613
TOLLIP 0 1.095 0.160 -0.150 -0.613

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TOLLIP Ubiquitylation K94 -0.411 0.859 _LNITVVQAK(gl)_
TOLLIP Ubiquitylation K97 0.276 _LAK(gl)NYGMTR_
TOLLIP Ubiquitylation K177 0.510 _QGK(gl)VEDKWYSLSGR_

Background Information for TOLLIP:


Pubmed-TOLLIP »
Uniprot-TOLLIP »
Biogrid-TOLLIP »
ProteomicsDB-TOLLIP »

Tumorportal-TOLLIP »
COSMIC-TOLLIP »
GenomeRNAi-TOLLIP »
Genecards-TOLLIP


Protein-protein Interactions for TOLLIP
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in TOLLIP
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members UBA-like IPR009060 0.17
Category members C2_dom IPR000008 0
Category members CUE IPR003892 0


Protein complexes (CORUM database) featuring TOLLIP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TOLLIP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members GO Category GO:0031625 ubiquitin protein ligase binding Database 2.54
Category members GO Category GO:0007267 cell-cell signaling Database 0.94
Category members GO Category GO:0033235 positive regulation of protein sumoylation Database 0.61
Category members Pathway Pathway_628 BIOCARTA_GSK3_PATHWAY 0 0.6
Category members GO Category GO:0006954 inflammatory response Database 0.49
Category members GO Category GO:0019900 kinase binding Database 0.45
Category members GO Category GO:0032183 SUMO binding Database 0.45
Category members Pathway Pathway_975 REACTOME_IL1_SIGNALING 0 0.42
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members Pathway Pathway_505 REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM 0 0.33
Category members GO Category GO:0016310 phosphorylation Database 0.21
Category members GO Category GO:0045087 innate immune response Database 0.05
Category members GO Category GO:0016604 nuclear body Database 0.04
Category members Pathway Pathway_1054 BIOCARTA_IL1R_PATHWAY 0 0
Category members Pathway Pathway_504 REACTOME_SIGNALING_BY_ILS 0 0
Category members Pathway Pathway_612 KEGG_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY 0 0
Category members Pathway Pathway_631 PID_IL1_PATHWAY 0 0
Category members Pathway Pathway_937 BIOCARTA_TOLL_PATHWAY 0 0
Category members GO Category GO:0004871 signal transducer activity Database 0
Category members GO Category GO:0005150 interleukin-1, Type I receptor binding Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0031624 ubiquitin conjugating enzyme binding Database 0
Category members GO Category GO:0035556 intracellular signal transduction Database 0
Category members GO Category GO:0045321 leukocyte activation Database 0
Category members GO Category GO:0045323 interleukin-1 receptor complex Database 0


.

© Copyright Svejstrup Laboratory 2015