bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: RBX1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RBX1 0 -1.738 0.920 -0.940 -0.015 -0.422

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RBX1 Ubiquitylation K19 -0.376 -0.371 _(ac)AAAMDVDTPSGTNSGAGK(gl)KR_
RBX1 Ubiquitylation K20 -0.541 -0.371 _(ac)AAAMDVDTPSGTNSGAGKK(gl)R_
RBX1 Phosphorylation T9 -0.553 _(ac)AAAMDVDT(ph)PSGTNSGAGK_

Background Information for RBX1:


Pubmed-RBX1 »
Uniprot-RBX1 »
Biogrid-RBX1 »
ProteomicsDB-RBX1 »

Tumorportal-RBX1 »
COSMIC-RBX1 »
GenomeRNAi-RBX1 »
Genecards-RBX1


Protein-protein Interactions for RBX1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATRX Cat. description Hein, Mann, Cell 2015
Category members IP bait BRWD3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CBX1 Cat. description Hein, Mann, Cell 2015
Category members IP bait COPS7A Cat. description Hein, Mann, Cell 2015
Category members IP bait CUL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CUL3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CUL4A Cat. description Hein, Mann, Cell 2015
Category members IP bait CUL4B Cat. description Hein, Mann, Cell 2015
Category members IP bait DDB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait DDB2 Cat. description Hein, Mann, Cell 2015
Category members IP bait DTL Cat. description Hein, Mann, Cell 2015
Category members IP bait EZH2 Cat. description Hein, Mann, Cell 2015
Category members IP bait LRR1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SRP72 Cat. description Hein, Mann, Cell 2015


Protein Domains in RBX1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_RING IPR001841 0


Protein complexes (CORUM database) featuring RBX1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 728 CSA-POLIIa complex Database 1.74
Category members Corum 726 DDB2 complex Database 1.33
Category members Corum 727 CSA complex Database 1.33
Category members Corum 1162 Ubiquitin E3 ligase (DDB1, DDB2, CUL4A, CUL4B, RBX1) Database 0.91
Category members Corum 2715 Ubiquitin E3 ligase (CSN1, CSN8, HRT1, SKP1, SKP2, CUL1, CUL2, CUL3) Database 0.61
Category members Corum 3015 p27-cyclinE-Cdk2 - Ubiquitin E3 ligase (SKP1A, SKP2, CUL1, CKS1B, RBX1) complex Database 0.28
Category members Corum 729 Ubiquitin E3 ligase (FBXO31, SKP1A, CUL1, RBX1) Database 0.17
Category members Corum 2722 Ubiquitin E3 ligase (DDB1, CUL4A, RBX1) Database 0.14
Category members Corum 391 Ubiquitin E3 ligase (DDB1, CUL4A, RBX1) Database 0.14
Category members Corum 2192 Ubiquitin E3 ligase (NIPA, SKP1A, CUL1, RBX1) Database 0.1
Category members Corum 81 Ubiquitin E3 ligase (SKP1A, FBXW8, CUL7, RBX1) Database 0.1
Category members Corum 219 CAND1-CUL1-RBX1 complex Database 0.06
Category members Corum 221 CAND1-CUL2-RBX1 complex Database 0.06
Category members Corum 222 CAND1-CUL3-RBX1 complex Database 0.06
Category members Corum 223 CAND1-CUL4A-RBX1 complex Database 0.06
Category members Corum 224 CAND1-CUL4B-RBX1 complex Database 0.06
Category members Corum 1211 Ubiquitin E3 ligase (AHR, ARNT, DDB1, TBL3, CUL4B, RBX1) Database 0.05
Category members Corum 1214 Ubiquitin E3 ligase (DET1, DDB1, CUL4A, RBX1, COP1) Database 0.04
Category members Corum 2172 Ubiquitin E3 ligase (CDT1, DDB1, CUL4A, RBX1) Database 0.04
Category members Corum 1052 Ubiquitin E3 ligase (FBXW11, SKP1A, CUL1, RBX1) Database 0.04
Category members Corum 2188 Ubiquitin E3 ligase (CDC34, NEDD8, BTRC, CUL1, SKP1A, RBX1) Database 0.04
Category members Corum 2189 Ubiquitin E3 ligase (SMAD3, BTRC, CUL1, SKP1A, RBX1) Database 0.04
Category members Corum 3036 Ubiquitin E3 ligase (SKP1A, SKP2, CUL1, CKS1B, RBX1) Database 0.04
Category members Corum 1051 Ubiquitin E3 ligase (SKP1A, SKP2, CUL1, RBX1) Database 0
Category members Corum 1215 Ubiquitin E3 ligase (FBXW7, CUL1, SKP1A, RBX1) Database 0
Category members Corum 1253 Ubiquitin E3 ligase (FBXW7, CUL1, SKP1A, RBX1) Database 0
Category members Corum 1258 Ubiquitin E3 ligase (GLMN, FBXW8, SKP1A, RBX1) Database 0
Category members Corum 1260 Neddylin ligase (FBXO11, SKP1, CUL1, RBX1) Database 0
Category members Corum 205 Ubiquitin E3 ligase (VHL, TCEB1, TCEB2, CUL2, RBX1) Database 0
Category members Corum 214 Ubiquitin E3 ligase (WSB1, TCEB1, TCEB2, CUL5, RBX1) Database 0
Category members Corum 2170 Ubiquitin E3 ligase (CDC34, CUL1, RBX1) Database 0
Category members Corum 2191 Ubiquitin E3 ligase (FBXO18, SKP1A, CUL1, RBX1) Database 0
Category members Corum 2881 Ubiquitin E3 ligase (CUL1, RBX1, SKP1A) Database 0
Category members Corum 4072 Heterotrimeric SKP1-CUL1-ROC1 complex Database 0
Category members Corum 80 Ubiquitin E3 ligase (Skp1A, Skp2, Cul1, Rbx1) Database 0


Categories featuring RBX1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0006281 DNA repair Database INF
Category members GO Category GO:0016032 viral process Database INF
Category members Pathway Pathway_197 REACTOME_HIV_INFECTION 0 12.07
Category members Pathway Pathway_196 REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS 0 9.67
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members Pathway Pathway_339 KEGG_NUCLEOTIDE_EXCISION_REPAIR 0 4.91
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members Pathway Pathway_223 KEGG_OOCYTE_MEIOSIS 0 2.71
Category members Pathway Pathway_764 REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION 0 2.56
Category members GO Category GO:0031625 ubiquitin protein ligase binding Database 2.54
Category members Pathway Pathway_888 KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS 0 2.22
Category members Pathway Pathway_866 KEGG_CELL_CYCLE 0 2.13
Category members Pathway Pathway_832 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION 0 1.58
Category members Pathway Pathway_796 REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G 0 1.14
Category members GO Category GO:0031461 cullin-RING ubiquitin ligase complex Database 0.77
Category members GO Category GO:0032403 protein complex binding Database 0.49
Category members Pathway Pathway_975 REACTOME_IL1_SIGNALING 0 0.42
Category members GO Category GO:0030163 protein catabolic process Database 0.38
Category members Pathway Pathway_753 REACTOME_REGULATION_OF_HYPOXIA_INDUCIBLE_FACTOR_HIF_BY_OXYGEN 0 0.35
Category members Pathway Pathway_505 REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM 0 0.33
Category members Pathway Pathway_117 REACTOME_SIGNALING_BY_NOTCH 0 0.33
Category members GO Category GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia Database 0.32
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members GO Category GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process Database 0.23
Category members Pathway Pathway_789 REACTOME_SIGNALING_BY_NOTCH1 0 0.22
Category members Pathway Pathway_893 KEGG_TGF_BETA_SIGNALING_PATHWAY 0 0.14
Category members Pathway Pathway_824 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION 0 0.14
Category members Pathway Pathway_974 REACTOME_PROLACTIN_RECEPTOR_SIGNALING 0 0.13
Category members Pathway Pathway_973 BIOCARTA_P27_PATHWAY 0 0.1
Category members GO Category GO:0045116 protein neddylation Database 0.1
Category members Pathway Pathway_679 KEGG_WNT_SIGNALING_PATHWAY 0 0.09
Category members GO Category GO:0019005 SCF ubiquitin ligase complex Database 0.09
Category members GO Category GO:0016567 protein ubiquitination Database 0.07
Category members Pathway Pathway_545 REACTOME_SIGNALING_BY_ERBB4 0 0.05
Category members GO Category GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process Database 0.05
Category members GO Category GO:0007219 Notch signaling pathway Database 0.05
Category members GO Category GO:0031465 Cul4B-RING ubiquitin ligase complex Database 0.04
Category members GO Category GO:0031464 Cul4A-RING ubiquitin ligase complex Database 0.04
Category members Pathway Pathway_23 KEGG_RENAL_CELL_CARCINOMA 0 0.03
Category members Pathway Pathway_821 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA 0 0
Category members Pathway Pathway_24 KEGG_PATHWAYS_IN_CANCER 0 0
Category members Pathway Pathway_504 REACTOME_SIGNALING_BY_ILS 0 0
Category members Pathway Pathway_976 PID_HIF1A_PATHWAY 0 0
Category members Pathway Pathway_977 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 0 0
Category members GO Category GO:0006513 protein monoubiquitination Database 0
Category members GO Category GO:0019788 NEDD8 ligase activity Database 0
Category members GO Category GO:0030891 VCB complex Database 0
Category members GO Category GO:0031462 Cul2-RING ubiquitin ligase complex Database 0
Category members GO Category GO:0031463 Cul3-RING ubiquitin ligase complex Database 0
Category members GO Category GO:0031466 Cul5-RING ubiquitin ligase complex Database 0
Category members GO Category GO:0071456 cellular response to hypoxia Database 0


.

© Copyright Svejstrup Laboratory 2015