Results for the Category
SCF ubiquitin ligase complex
(GO:0019005)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| FBXO4 | 2 | -0.890 | 1.280 | |||||
| USP47 | 2 | 0.370 | -0.540 | 1.392 | ||||
| USP47 | 2 | 0.370 | -0.540 | |||||
| CUL1 | 1 | 0.630 | -0.610 | -0.314 | 0.662 | 2.069 | 0.342 | 0.118 |
| FBXW8 | 1 | 2.140 | -1.050 | -0.439 | 0.088 | |||
| FBXL3 | 0 | -0.990 | 1.600 | |||||
| FBXW11 | 0 | -0.780 | 0.530 | 0.532 | -1.791 | 0.313 | ||
| FBXL19 | 0 | 0.290 | -0.460 | |||||
| RBX1 | 0 | 0.920 | -0.940 | -0.015 | -0.422 | |||
| SKP1 | 0 | 1.470 | -0.970 | -1.305 | -0.243 | -0.093 | 0.054 | |
| SKP1 | 0 | 1.470 | -0.970 | -0.472 | ||||
| FBXL5 | 0 | -1.220 | 1.350 | |||||
| TRIM21 | 0 | -0.230 | -0.010 | -0.266 | -0.252 | |||
| SKP2 | 0 | 0.030 | 0.690 | |||||
| SKP2 | 0 | 0.030 | 0.690 | |||||
| FBXW5 | 0 | 0.640 | -0.720 | |||||
| CCNF | 0 | 0.710 | -0.520 | |||||
| BTRC | 0 | -0.780 | 0.690 | 0.532 | -1.791 | 0.313 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| BTRC | Ubiquitylation | K466 | 0.325 | _IVSGAYDGKIK(gl)_ | |
| CCNF | Ubiquitylation | K514 | 0.681 | _QVSLTAVK(gl)QR_ | |
| CUL1 | Ubiquitylation | K262 | 0.119 | _ESTEFLQQNPVTEYMK(gl)K_ | |
| CUL1 | Ubiquitylation | K263 | 0.119 | -0.055 | _ESTEFLQQNPVTEYMK(gl)K_ |
| CUL1 | Ubiquitylation | K410 | 0.250 | 0.326 | _FINNNAVTK(gl)MAQSSSK_ |
| CUL1 | Ubiquitylation | K417 | 0.761 | _MAQSSSK(gl)SPELLAR_ | |
| CUL1 | Ubiquitylation | K468 | 1.237 | _FYAK(gl)MLAK_ | |
| CUL1 | Ubiquitylation | K503 | 0.665 | _QACGFEYTSK(gl)LQR_ | |
| CUL1 | Ubiquitylation | K769 | 0.292 | _VDGEK(gl)DTYSYLA_ | |
| FBXL19 | Ubiquitylation | K561 | -3.621 | _ELLLPPPDTK(gl)PGQTESR_ | |
| FBXL3 | Ubiquitylation | K321 | -0.415 | _SVSK(gl)DVLGR_ | |
| FBXL5 | Ubiquitylation | K100 | -0.676 | _NVK(gl)NEYEQLNYAK_ | |
| FBXL5 | Ubiquitylation | K162 | -1.311 | _VIAQHCSQK(gl)DTAELLR_ | |
| FBXL5 | Ubiquitylation | K403 | -1.057 | _ITDVALEK(gl)ISR_ | |
| FBXL5 | Ubiquitylation | K582 | -0.131 | _GK(gl)DLIYFGSEK_ | |
| FBXO4 | Phosphorylation | S12 | -0.857 | -0.593 | _SGTNS(ph)PPPPFSDWGR_ |
| FBXO4 | Ubiquitylation | K40 | 0.111 | _TFWQSVSK(gl)ER_ | |
| FBXO4 | Phosphorylation | S48 | 2.764 | 2.416 | _TTS(ph)REEVDEAASTLTR_ |
| FBXW11 | Ubiquitylation | K466 | 0.325 | _IVSGAYDGKIK(gl)_ | |
| FBXW5 | Ubiquitylation | K240 | 0.526 | _LFK(gl)IQNLNASTVR_ | |
| FBXW5 | Phosphorylation | S275 | -0.621 | _FDSPDLLLEAGDPATS(ph)PCR_ | |
| FBXW5 | Ubiquitylation | K337 | -1.751 | _VAELLAQGHTK(gl)PPER_ | |
| RBX1 | Phosphorylation | T9 | -0.553 | _(ac)AAAMDVDT(ph)PSGTNSGAGK_ | |
| RBX1 | Ubiquitylation | K19 | -0.376 | -0.371 | _(ac)AAAMDVDTPSGTNSGAGK(gl)KR_ |
| RBX1 | Ubiquitylation | K20 | -0.541 | -0.371 | _(ac)AAAMDVDTPSGTNSGAGKK(gl)R_ |
| SKP1 | Ubiquitylation | K130 | 0.138 | 0.140 | _GK(gl)TPEEIRK_ |
| SKP1 | Phosphorylation | T131 | -0.024 | -0.138 | _GKT(ph)PEEIRK_ |
| SKP1 | Ubiquitylation | K142 | 0.165 | 0.894 | _TFNIK(gl)NDFTEEEEAQVRK_ |
| SKP1 | Ubiquitylation | K155 | -0.096 | 0.069 | _K(gl)ENQWCEEK_ |
| SKP1 | Ubiquitylation | K163 | 0.109 | -0.020 | _ENQWCEEK(gl)_ |
| SKP2 | Phosphorylation | S8 | -1.062 | _SNLGHPES(ph)PPRK_ | |
| SKP2 | Phosphorylation | S64 | -1.144 | -1.189 | _EEPDSENIPQELLSNLGHPES(ph)PPR_ |
| SKP2 | Phosphorylation | S75 | 0.512 | 0.657 | _SKGS(ph)DKDFVIVR_ |
| SKP2 | Ubiquitylation | K228 | -0.475 | _LSDPIVNTLAK(gl)NSNLVR_ | |
| SKP2 | Ubiquitylation | K420 | -1.178 | _LTLQK(gl)PSCL_ | |
| USP47 | Phosphorylation | S832 | 0.001 | -0.284 | _LFVLLPEQS(ph)PVSYSK_ |
| USP47 | Phosphorylation | S910 | 1.689 | 2.323 | _STETSDFENIES(ph)PLNER_ |
| USP47 | Phosphorylation | T932 | 0.805 | _ELEQHIQT(ph)SDPENFQSEER_ | |
| USP47 | Phosphorylation | S933 | 0.302 | 0.148 | _ELEQHIQTS(ph)DPENFQSEER_ |
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