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Query: FBXL5

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
FBXL5 0 1.219 -1.220 1.350

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
FBXL5 Ubiquitylation K582 -0.131 _GK(gl)DLIYFGSEK_
FBXL5 Ubiquitylation K100 -0.676 _NVK(gl)NEYEQLNYAK_
FBXL5 Ubiquitylation K403 -1.057 _ITDVALEK(gl)ISR_
FBXL5 Ubiquitylation K162 -1.311 _VIAQHCSQK(gl)DTAELLR_

Background Information for FBXL5:


Pubmed-FBXL5 »
Uniprot-FBXL5 »
Biogrid-FBXL5 »
ProteomicsDB-FBXL5 »

Tumorportal-FBXL5 »
COSMIC-FBXL5 »
GenomeRNAi-FBXL5 »
Genecards-FBXL5


Protein-protein Interactions for FBXL5
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait FBXL5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in FBXL5
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Leu-rich_rpt IPR001611 0.32
Category members F-box_dom IPR001810 0
Category members Leu-rich_rpt_Cys-con_subtyp IPR006553 0


Protein complexes (CORUM database) featuring FBXL5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring FBXL5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members Pathway Pathway_742 REACTOME_PROTEIN_FOLDING 0 0.9
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members Pathway Pathway_741 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS 0 0.29
Category members GO Category GO:0000151 ubiquitin ligase complex Database 0.24
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members GO Category GO:0019005 SCF ubiquitin ligase complex Database 0.09
Category members GO Category GO:0016567 protein ubiquitination Database 0.07
Category members GO Category GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process Database 0.05
Category members GO Category GO:0005506 iron ion binding Database 0.04
Category members GO Category GO:0055072 iron ion homeostasis Database 0


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