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REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS
(Pathway_741)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
FBXO4 2 -0.890 1.280
TCP1 1 0.910 -0.350 -0.279 -0.943 -0.582 0.460 0.439
ARFGEF2 1 -0.840 1.310 2.230
CCT7 1 -0.930 1.460
CCT7 1 -0.930 1.460 -0.370 -0.710 -0.502
CCT3 1 -0.440 0.600 -0.440 -0.698 -0.560 -0.040 -0.114
CCT2 1 -1.960 4.690 -0.103 -0.462 -0.504 0.251 0.451
AP3M1 1 2.120 -1.010 -0.529 -0.213 -0.553
FBXL3 0 -0.990 1.600
XRN2 0 1.050 -0.930 -2.506 -1.121 -0.161 -0.293 -0.304
NOP56 0 -0.250 0.440
NOP56 0 -0.250 0.440 0.498 0.422
USP11 0 0.840 -0.200 -0.333 0.001 0.704
LONP2 0 0.380 -0.520 -0.179 0.071
CCT4 0 0.170 -0.060 -0.745 -0.586 0.025 0.190
CCT4 0 0.170 -0.060 -0.246
FBXL5 0 -1.220 1.350
FBXW2 0 -0.930 1.120
FKBP9 0 0.130 0.150
FKBP9 0 0.720 -0.450
KIF13A 0 -1.390 2.280
CCT6A 0 0.330 -0.060 -0.116 -0.788 -0.510 0.477 0.245
CCT6A 0 0.330 -0.060
CCT5 0 0.340 -0.350 -0.024 -0.479 -0.463 0.276 0.342
CCT8 0 0.440 0.010 -0.129 -0.611 -0.510 0.526 0.536
FBXW5 0 0.640 -0.720

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
AP3M1 Ubiquitylation K283 -0.147 _HSISFK(gl)ENSSCGR_
AP3M1 Ubiquitylation K413 -0.636 -0.807 _AGK(gl)FQVR_
ARFGEF2 Phosphorylation S214 0.250 _ELEKPIQS(ph)KPQSPVIQAAAVS(ph)PK_
ARFGEF2 Phosphorylation S218 -0.081 0.177 _ELEKPIQSKPQS(ph)PVIQAAAVS(ph)PK_
ARFGEF2 Phosphorylation S227 -1.086 -0.941 _ELEKPIQSKPQS(ph)PVIQAAAVS(ph)PK_
ARFGEF2 Phosphorylation S276 0.922 0.963 _GS(ph)SLSGTDDGAQEVVK_
ARFGEF2 Phosphorylation S277 0.851 0.904 _GSS(ph)LSGTDDGAQEVVK_
ARFGEF2 Phosphorylation S1528 -0.424 0.473 _GQSQLS(ph)NPTDDSWK_
CCT2 Ubiquitylation K13 -0.609 _(ac)ASLSLAPVNIFK(gl)AGADEERAETAR_
CCT2 Ubiquitylation K46 0.429 _STLGPK(gl)GMDK_
CCT2 Ubiquitylation K50 -0.136 _GMDK(gl)ILLSSGR_
CCT2 Ubiquitylation K82 -0.230 0.384 _NIGVDNPAAK(gl)VLVDMSR_
CCT2 Ubiquitylation K120 0.281 0.305 _EAESLIAKK(gl)_
CCT2 Ubiquitylation K154 0.317 0.803 _EALLSSAVDHGSDEVK(gl)FR_
CCT2 Ubiquitylation K248 0.491 0.333 _ILIANTGMDTDK(gl)IK_
CCT2 Ubiquitylation K284 0.170 _ILK(gl)HGINCFINR_
CCT2 Ubiquitylation K431 -0.401 _TPGK(gl)EAVAMESYAK_
CCT2 Ubiquitylation K441 0.095 -0.071 _EAVAM(ox)ESYAK(gl)ALR_
CCT2 Ubiquitylation K522 0.245 0.094 _VDNIIK(gl)AAPR_
CCT3 Ubiquitylation K47 -0.257 -0.017 _(ac)MMGHRPVLVLSQNTK(gl)R_
CCT3 Ubiquitylation K53 0.139 _K(gl)VQSGNINAAK_
CCT3 Ubiquitylation K76 -0.108 0.263 _TCLGPK(gl)SMMK_
CCT3 Ubiquitylation K110 -1.269 -0.318 _EIQVQHPAAK(gl)SMIEISR_
CCT3 Ubiquitylation K170 0.828 _ALDDMISTLK(gl)K_
CCT3 Ubiquitylation K171 0.828 _ALDDMISTLK(gl)K_
CCT3 Ubiquitylation K254 -0.399 0.229 _GVMINK(gl)DVTHPR_
CCT3 Ubiquitylation K281 -0.289 _K(gl)GESQTDIEITREEDFTR_
CCT3 Phosphorylation S284 0.252 1.757 _KGES(ph)QTDIEITR_
CCT3 Ubiquitylation K413 0.089 0.018 _GASK(gl)EILSEVER_
CCT3 Ubiquitylation K459 -0.570 -0.290 _SK(gl)AMTGVEQWPYR_
CCT3 Ubiquitylation K539 0.817 0.868 _LQTYK(gl)TAVETAVLLLR_
CCT3 Ubiquitylation K559 0.150 _IDDIVSGHK(gl)K_
CCT3 Ubiquitylation K560 0.911 0.233 _IDDIVSGHKK(gl)_
CCT4 Ubiquitylation K42 -0.386 _FSNISAAK(gl)AVADAIR_
CCT4 Ubiquitylation K55 0.262 0.410 _TSLGPK(gl)GMDK_
CCT4 Ubiquitylation K65 -0.085 0.273 _MIQDGK(gl)GDVTITNDGATILK_
CCT4 Ubiquitylation K126 -0.473 _LLQK(gl)GIHPTIISESFQK_
CCT4 Ubiquitylation K291 0.366 _AYILNLVKQIK(gl)_
CCT4 Ubiquitylation K292 -0.083 _K(gl)TGCNVLLIQK_
CCT4 Ubiquitylation K375 -0.019 _LLK(gl)ITGCASPGK_
CCT4 Ubiquitylation K395 0.067 _GSNK(gl)LVIEEAER_
CCT4 Ubiquitylation K489 -0.142 _HAQGEK(gl)TAGINVR_
CCT4 Ubiquitylation K531 0.360 _SILK(gl)IDDVVNTR_
CCT5 Ubiquitylation K42 -0.197 _SHIMAAK(gl)AVANTMR_
CCT5 Ubiquitylation K176 0.077 -0.089 _TTLGSK(gl)VVNSCHR_
CCT5 Ubiquitylation K223 0.209 -0.071 _LEDTK(gl)LIK_
CCT5 Ubiquitylation K265 0.295 _HK(gl)LDVTSVEDYK_
CCT5 Ubiquitylation K275 0.003 -0.937 _LDVTSVEDYK(gl)ALQK_
CCT5 Ubiquitylation K279 -0.233 _ALQK(gl)YEK_
CCT5 Ubiquitylation K370 0.104 _DK(gl)MLVIEQCK_
CCT5 Ubiquitylation K378 0.652 -0.023 _MLVIEQCK(gl)NSR_
CCT5 Ubiquitylation K392 -0.223 _GGNK(gl)M(ox)IIEEAK(gl)R_
CCT5 Ubiquitylation K399 0.453 -0.110 _M(ox)IIEEAK(gl)R_
CCT5 Ubiquitylation K483 -0.464 -0.608 _QVK(gl)EMNPALGIDCLHK_
CCT5 Ubiquitylation K496 -0.925 _EMNPALGIDCLHK(gl)GTNDMK_
CCT5 Ubiquitylation K514 0.076 0.212 _K(gl)QQISLATQMVR_
CCT5 Ubiquitylation K529 -0.016 -0.280 _MILK(gl)IDDIR_
CCT5 Ubiquitylation K535 -0.002 -0.302 _IDDIRK(gl)PGESEE_
CCT6A Ubiquitylation K5 -0.911 -0.385 _(ac)AAVK(gl)TLNPK(gl)AEVAR_
CCT6A Ubiquitylation K10 -0.519 1.185 _TLNPK(gl)AEVAR_
CCT6A Ubiquitylation K41 -0.001 0.417 _TNLGPK(gl)GTMK_
CCT6A Ubiquitylation K127 0.601 0.073 _IITEGFEAAK(gl)EK_
CCT6A Ubiquitylation K129 0.572 0.697 _EK(gl)ALQFLEEVK_
CCT6A Ubiquitylation K199 -0.073 _HK(gl)SETDTSLIR_
CCT6A Ubiquitylation K280 0.578 _K(gl)VCGDSDKGFVVINQK_
CCT6A Ubiquitylation K365 -0.522 -0.685 _FTFIEK(gl)CNNPR_
CCT6A Ubiquitylation K377 0.067 0.134 _SVTLLIK(gl)GPNK_
CCT6A Ubiquitylation K381 0.062 _GPNK(gl)HTLTQIK_
CCT6A Ubiquitylation K530 -0.356 0.874 _AGMSSLK(gl)G_
CCT7 Ubiquitylation K3 -0.028 _DK(gl)LIVDGR_
CCT7 Ubiquitylation K47 -0.134 0.102 _GMDK(gl)LIVDGR_
CCT7 Ubiquitylation K55 0.132 0.539 _GK(gl)ATISNDGATILK_
CCT7 Ubiquitylation K93 0.705 0.445 _TATQLAVNKIK(gl)_
CCT7 Ubiquitylation K135 -0.024 _TATQLAVNK(gl)IK_
CCT7 Ubiquitylation K137 0.751 0.445 _IK(gl)EIAVTVK_
CCT7 Ubiquitylation K144 -0.296 -0.470 _IKEIAVTVK(gl)K_
CCT7 Ubiquitylation K145 -0.578 -0.520 _EIAVTVKK(gl)_
CCT7 Ubiquitylation K166 -0.249 _CAMTALSSK(gl)LISQQK_
CCT7 Ubiquitylation K172 -0.992 0.276 _LISQQK(gl)AFFAK_
CCT7 Ubiquitylation K218 -0.512 _K(gl)TFSYAGFEMQPK_
CCT7 Ubiquitylation K231 3.208 _TFSYAGFEMQPKK(gl)_
CCT7 Ubiquitylation K320 -0.528 -0.410 _VPEEDLK(gl)R_
CCT7 Ubiquitylation K366 -0.687 -0.358 _YNFFTGCPK(gl)AK_
CCT7 Ubiquitylation K368 1.686 1.109 _AK(gl)TCTFILR_
CCT7 Ubiquitylation K430 -1.102 -1.136 _TIPGK(gl)QQLLIGAYAK_
CCT7 Ubiquitylation K463 -0.247 0.130 _QLCDNAGFDATNILNK(gl)LR_
CCT8 Ubiquitylation K7 -0.282 -0.604 _(ac)ALHVPK(gl)APGFAQMLK_
CCT8 Ubiquitylation K16 -0.003 -0.077 _APGFAQM(ox)LK(gl)EGAK_
CCT8 Ubiquitylation K20 0.278 0.511 _EGAK(gl)HFSGLEEAVYR_
CCT8 Ubiquitylation K37 0.439 0.860 _NIQACK(gl)ELAQTTR_
CCT8 Ubiquitylation K152 -0.270 _AHEILPNLVCCSAK(gl)NLR_
CCT8 Ubiquitylation K171 1.213 _TSIMSK(gl)QYGNEVFLAK_
CCT8 Ubiquitylation K235 0.538 1.082 _ETEGDVTSVK(gl)DAK_
CCT8 Ubiquitylation K238 0.548 _ETEGDVTSVK(gl)DAK_
CCT8 Ubiquitylation K260 0.152 _GTVLIK(gl)TAEELMNFSK_
CCT8 Ubiquitylation K270 0.187 _TAEELMNFSK(gl)GEENLMDAQVK_
CCT8 Ubiquitylation K318 -0.421 1.097 _LNSK(gl)WDLRR_
CCT8 Ubiquitylation K326 0.065 0.098 _RLCK(gl)TVGATALPR_
CCT8 Ubiquitylation K400 0.364 0.867 _AVDDGVNTFK(gl)VLTR_
CCT8 Ubiquitylation K440 -0.342 _K(gl)FAEAFEAIPR_
CCT8 Ubiquitylation K459 -0.052 0.061 _ALAENSGVK(gl)ANEVISK_
CCT8 Ubiquitylation K466 0.068 _ANEVISK(gl)LYAVHQEGNK_
CCT8 Ubiquitylation K528 -1.602 _VDQIIMAK(gl)PAGGPKPPSGK_
CCT8 Ubiquitylation K534 -2.257 _VDQIIMAKPAGGPK(gl)PPSGK_
CCT8 Phosphorylation S537 -1.069 -1.022 _PAGGPKPPS(ph)GK_
CCT8 Ubiquitylation K540 -1.770 _PAGGPKPPSGKK(gl)_
FBXL3 Ubiquitylation K321 -0.415 _SVSK(gl)DVLGR_
FBXL5 Ubiquitylation K100 -0.676 _NVK(gl)NEYEQLNYAK_
FBXL5 Ubiquitylation K162 -1.311 _VIAQHCSQK(gl)DTAELLR_
FBXL5 Ubiquitylation K403 -1.057 _ITDVALEK(gl)ISR_
FBXL5 Ubiquitylation K582 -0.131 _GK(gl)DLIYFGSEK_
FBXO4 Phosphorylation S12 -0.857 -0.593 _SGTNS(ph)PPPPFSDWGR_
FBXO4 Ubiquitylation K40 0.111 _TFWQSVSK(gl)ER_
FBXO4 Phosphorylation S48 2.764 2.416 _TTS(ph)REEVDEAASTLTR_
FBXW2 Ubiquitylation K125 0.811 _VYLK(gl)AILR_
FBXW5 Ubiquitylation K240 0.526 _LFK(gl)IQNLNASTVR_
FBXW5 Phosphorylation S275 -0.621 _FDSPDLLLEAGDPATS(ph)PCR_
FBXW5 Ubiquitylation K337 -1.751 _VAELLAQGHTK(gl)PPER_
FKBP9 Ubiquitylation K271 1.202 _GLLGMCVGEK(gl)R_
FKBP9 Ubiquitylation K494 0.021 _EMCVGEK(gl)R_
KIF13A Phosphorylation S1738 0.143 -0.064 _TGS(ph)CSELDACPSK_
NOP56 Ubiquitylation K87 0.017 0.312 _LLLETHLPSK(gl)K_
NOP56 Ubiquitylation K88 0.481 _LLLETHLPSK(gl)K_
NOP56 Ubiquitylation K242 0.929 0.112 _AK(gl)AILDASR_
NOP56 Ubiquitylation K375 0.885 0.941 _YLANK(gl)CSIASR_
NOP56 Ubiquitylation K396 0.566 0.769 _IDCFSEVPTSVFGEK(gl)LR_
NOP56 Phosphorylation S462 0.167 _RLAALALASS(ph)ENSSSTPEECEEM(ox)SEKPK_
NOP56 Phosphorylation T468 0.257 0.616 _RLAALALASSENSSST(ph)PEECEEM(ox)SEKPK_
NOP56 Phosphorylation S519 0.580 0.502 _EELM(ox)S(ph)SDLEETAGSTSIPK_
NOP56 Phosphorylation S520 0.490 0.392 _SFSKEELMSS(ph)DLEETAGSTSIPK_
NOP56 Phosphorylation S563 1.180 0.504 _FS(ph)KEEPVSSGPEEAVGK_
NOP56 Phosphorylation S569 -0.374 -0.072 _EEPVS(ph)SGPEEAVGK_
NOP56 Phosphorylation S570 -0.169 -0.059 _EEPVSS(ph)GPEEAVGK_
TCP1 Ubiquitylation K109 -0.135 0.674 _NADELVK(gl)QK_
TCP1 Ubiquitylation K126 -0.013 0.696 _LACK(gl)EAVR_
TCP1 Ubiquitylation K153 1.172 _DCLINAAK(gl)TSMSSK_
TCP1 Ubiquitylation K365 2.257 _ICDDELILIK(gl)NTK_
TCP1 Ubiquitylation K400 0.670 0.460 _SLHDALCVVK(gl)R_
TCP1 Ubiquitylation K532 -0.204 -0.345 _IDDLIK(gl)LHPESK_
TCP1 Phosphorylation S544 0.593 0.207 _HGS(ph)YEDAVHSGALND_
USP11 Ubiquitylation K245 -0.175 -0.284 _LWAK(gl)NSEGSLDR_
USP11 Ubiquitylation K385 -0.348 _SIVPHVFKNK(gl)_
USP11 Phosphorylation S733 0.908 0.540 _TTS(ph)PEEVHAQPYIAIDWEPEMK_
USP11 Ubiquitylation K776 -0.145 0.017 _HDCVGYVM(ox)KK(gl)_
USP11 Ubiquitylation K835 0.273 0.465 _FSYTK(gl)FSR_
XRN2 Ubiquitylation K132 0.183 _EGMEAAVEK(gl)QR_
XRN2 Phosphorylation T439 -0.332 -1.539 _RDQPAFTPSGILT(ph)PHALGSR_
XRN2 Phosphorylation S448 0.425 0.037 _NS(ph)PGSQVASNPR_
XRN2 Phosphorylation S473 0.104 -0.751 _MQNNSSPS(ph)ISPNTSFTSDGSPSPLGGIK_
XRN2 Phosphorylation S475 0.436 _MQNNSSPSIS(ph)PNTSFTSDGSPSPLGGIK_
XRN2 Ubiquitylation K493 -1.223 _MQNNSSPSISPNTSFTSDGSPSPLGGIK(gl)R_
XRN2 Phosphorylation S499 -1.444 _AEDS(ph)DSEPEPEDNVR_
XRN2 Ubiquitylation K533 0.431 _NKFDVDAADEK(gl)FR_


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