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Query: NOP56

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
NOP56 0 5.026 -0.250 0.440
NOP56 0 5.026 -0.250 0.440 0.498 0.422

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
NOP56 Ubiquitylation K375 0.885 0.941 _YLANK(gl)CSIASR_
NOP56 Ubiquitylation K396 0.566 0.769 _IDCFSEVPTSVFGEK(gl)LR_
NOP56 Phosphorylation T468 0.257 0.616 _RLAALALASSENSSST(ph)PEECEEM(ox)SEKPK_
NOP56 Phosphorylation S563 1.180 0.504 _FS(ph)KEEPVSSGPEEAVGK_
NOP56 Phosphorylation S519 0.580 0.502 _EELM(ox)S(ph)SDLEETAGSTSIPK_
NOP56 Ubiquitylation K88 0.481 _LLLETHLPSK(gl)K_
NOP56 Phosphorylation S520 0.490 0.392 _SFSKEELMSS(ph)DLEETAGSTSIPK_
NOP56 Ubiquitylation K87 0.017 0.312 _LLLETHLPSK(gl)K_
NOP56 Phosphorylation S462 0.167 _RLAALALASS(ph)ENSSSTPEECEEM(ox)SEKPK_
NOP56 Ubiquitylation K242 0.929 0.112 _AK(gl)AILDASR_
NOP56 Phosphorylation S570 -0.169 -0.059 _EEPVSS(ph)GPEEAVGK_
NOP56 Phosphorylation S569 -0.374 -0.072 _EEPVS(ph)SGPEEAVGK_

Background Information for NOP56:





Protein-protein Interactions for NOP56

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait FBL Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPU Cat. description Hein, Mann, Cell 2015
Category members IP bait NOP56 Cat. description Hein, Mann, Cell 2015
Category members IP bait NPM1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RRBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SRP72 Cat. description Hein, Mann, Cell 2015
Category members IP bait CNBP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM196A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FBL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FMR1NB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPATCH4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NEUROG3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait P2RX5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBM4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL18 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL37A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RRS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TNFRSF19 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in NOP56

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members NOP5_N IPR012974 0.34
Category members Nop_dom IPR002687 0.11
Category members NOSIC IPR012976 0.11


Protein complexes (CORUM database) featuring NOP56

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 3055 Nop56p-associated pre-rRNA complex Database INF


Categories featuring NOP56

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0006364 rRNA processing Database 2.47
Category members Pathway Pathway_742 REACTOME_PROTEIN_FOLDING 0 0.9
Category members GO Category GO:0031428 box C/D snoRNP complex Database 0.79
Category members Pathway Pathway_741 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS 0 0.29
Category members GO Category GO:0008219 cell death Database 0.08
Category members GO Category GO:0030515 snoRNA binding Database 0.07
Category members GO Category GO:0005732 small nucleolar ribonucleoprotein complex Database 0
Category members GO Category GO:0070761 pre-snoRNP complex Database 0


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