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Query: FBXW2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
FBXW2 0 1.931 -0.930 1.120

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
FBXW2 Ubiquitylation K125 0.811 _VYLK(gl)AILR_

Background Information for FBXW2:





Protein-protein Interactions for FBXW2

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait FBXO7 Cat. description Hein, Mann, Cell 2015
Category members IP bait ARIH1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BTRC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FBXO17 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FBXO7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FBXW7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPANXN3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in FBXW2

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WD40_repeat_dom IPR017986 1.39
Category members WD40_repeat IPR001680 0.52
Category members G-protein_beta_WD-40_rep IPR020472 0.12
Category members F-box_dom IPR001810 0


Protein complexes (CORUM database) featuring FBXW2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 390 Ubiquitin E3 ligase (SKP1A, FBXW2, CUL1) Database 0


Categories featuring FBXW2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members Pathway Pathway_742 REACTOME_PROTEIN_FOLDING 0 0.9
Category members Pathway Pathway_741 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS 0 0.29
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members GO Category GO:0016567 protein ubiquitination Database 0.07
Category members Pathway Pathway_290 WNT_SIGNALING 0 0
Category members GO Category GO:0006464 cellular protein modification process Database 0
Category members GO Category GO:0006508 proteolysis Database 0


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