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Query: CCT7

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CCT7 1 4.195 -0.930 1.460
CCT7 1 4.195 -0.930 1.460 -0.370 -0.710 -0.502

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CCT7 Ubiquitylation K368 1.686 1.109 _AK(gl)TCTFILR_
CCT7 Ubiquitylation K55 0.132 0.539 _GK(gl)ATISNDGATILK_
CCT7 Ubiquitylation K93 0.705 0.445 _TATQLAVNKIK(gl)_
CCT7 Ubiquitylation K137 0.751 0.445 _IK(gl)EIAVTVK_
CCT7 Ubiquitylation K172 -0.992 0.276 _LISQQK(gl)AFFAK_
CCT7 Ubiquitylation K463 -0.247 0.130 _QLCDNAGFDATNILNK(gl)LR_
CCT7 Ubiquitylation K47 -0.134 0.102 _GMDK(gl)LIVDGR_
CCT7 Ubiquitylation K135 -0.024 _TATQLAVNK(gl)IK_
CCT7 Ubiquitylation K366 -0.687 -0.358 _YNFFTGCPK(gl)AK_
CCT7 Ubiquitylation K320 -0.528 -0.410 _VPEEDLK(gl)R_
CCT7 Ubiquitylation K144 -0.296 -0.470 _IKEIAVTVK(gl)K_
CCT7 Ubiquitylation K218 -0.512 _K(gl)TFSYAGFEMQPK_
CCT7 Ubiquitylation K145 -0.578 -0.520 _EIAVTVKK(gl)_
CCT7 Ubiquitylation K430 -1.102 -1.136 _TIPGK(gl)QQLLIGAYAK_
CCT7 Ubiquitylation K3 -0.028 _DK(gl)LIVDGR_
CCT7 Ubiquitylation K166 -0.249 _CAMTALSSK(gl)LISQQK_
CCT7 Ubiquitylation K231 3.208 _TFSYAGFEMQPKK(gl)_

Background Information for CCT7:


Pubmed-CCT7 »
Uniprot-CCT7 »
Biogrid-CCT7 »
ProteomicsDB-CCT7 »

Tumorportal-CCT7 »
COSMIC-CCT7 »
GenomeRNAi-CCT7 »
Genecards-CCT7


Protein-protein Interactions for CCT7
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTR2 Cat. description Hein, Mann, Cell 2015
Category members IP bait ARMC6 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCT2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCT3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCT4 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCT7 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCT8 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDC20 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDK1 Cat. description Hein, Mann, Cell 2015
Category members IP bait DDB2 Cat. description Hein, Mann, Cell 2015
Category members IP bait DTL Cat. description Hein, Mann, Cell 2015
Category members IP bait GNB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait HDAC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait IGBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ILK Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF21A Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF21B Cat. description Hein, Mann, Cell 2015
Category members IP bait NEDD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NIPSNAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NSMAF Cat. description Hein, Mann, Cell 2015
Category members IP bait PDK3 Cat. description Hein, Mann, Cell 2015
Category members IP bait PFDN2 Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP2CA Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP2CB Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP4C Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP6C Cat. description Hein, Mann, Cell 2015
Category members IP bait PRPF4 Cat. description Hein, Mann, Cell 2015
Category members IP bait RFWD3 Cat. description Hein, Mann, Cell 2015
Category members IP bait SAMM50 Cat. description Hein, Mann, Cell 2015
Category members IP bait SEH1L Cat. description Hein, Mann, Cell 2015
Category members IP bait STRN Cat. description Hein, Mann, Cell 2015
Category members IP bait STRN3 Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBA1C Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBA3C;TUBA3E Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBG1 Cat. description Hein, Mann, Cell 2015
Category members IP bait WDR48 Cat. description Hein, Mann, Cell 2015
Category members IP bait WDR61 Cat. description Hein, Mann, Cell 2015
Category members IP bait WRAP53 Cat. description Hein, Mann, Cell 2015
Category members IP bait ACTBL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ACTR1B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ACTR3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ACTR3B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ANGPTL7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCT3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCT7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDC20 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DCAF10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DCAF11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DCAF5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DCAF7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DCAF8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DDB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DNAI2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FBXW4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GNB1L Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GNB5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HCFC2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HDAC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KATNA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KDM4B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLHDC8A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLHL33 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MLST8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NOL10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ODF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait P4HA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PEX7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait POC1A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPP2R2C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAP2C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RFWD2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPTOR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SEC31B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STRADB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TBL1Y Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSSC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TTLL3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TUBA1B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TUBA4A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TUBAL3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TUBG2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TXNDC9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDR25 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDR5B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDR83 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDR86 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CCT7
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Chaprnin_Cpn60 IPR001844 0.33
Category members Cpn60/TCP-1 IPR002423 0.09
Category members GroEL-like_apical_dom IPR027409 0.09
Category members Chaperone_TCP-1 IPR017998 0.07


Protein complexes (CORUM database) featuring CCT7
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 126 CCT micro-complex Database 0.06


Categories featuring CCT7
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0006457 protein folding Database 4.93
Category members GO Category GO:0051082 unfolded protein binding Database 3.74
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0005874 microtubule Database 1.21
Category members Pathway Pathway_742 REACTOME_PROTEIN_FOLDING 0 0.9
Category members GO Category GO:0051084 'de novo' posttranslational protein folding Database 0.63
Category members Pathway Pathway_1288 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC 0 0.4
Category members Pathway Pathway_741 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS 0 0.29
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members Pathway Pathway_1296 REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC 0 0.08
Category members GO Category GO:0002199 zona pellucida receptor complex Database 0.07
Category members GO Category GO:0005832 chaperonin-containing T-complex Database 0.06
Category members GO Category GO:0007339 binding of sperm to zona pellucida Database 0
Category members GO Category GO:0044297 cell body Database 0


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