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Query: FBXL3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
FBXL3 0 1.185 -0.990 1.600

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
FBXL3 Ubiquitylation K321 -0.415 _SVSK(gl)DVLGR_

Background Information for FBXL3:


Pubmed-FBXL3 »
Uniprot-FBXL3 »
Biogrid-FBXL3 »
ProteomicsDB-FBXL3 »

Tumorportal-FBXL3 »
COSMIC-FBXL3 »
GenomeRNAi-FBXL3 »
Genecards-FBXL3


Protein-protein Interactions for FBXL3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait FBXL3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in FBXL3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members F-box_dom IPR001810 0


Protein complexes (CORUM database) featuring FBXL3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2772 Ubiquitin E3 ligase (CRY1, SKP1A, CUL1, FBXL3) Database 0
Category members Corum 2773 Ubiquitin E3 ligase (CRY2, SKP1A, CUL1, FBXL3) Database 0


Categories featuring FBXL3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members Pathway Pathway_157 REACTOME_CIRCADIAN_CLOCK 0 0.92
Category members Pathway Pathway_742 REACTOME_PROTEIN_FOLDING 0 0.9
Category members Pathway Pathway_741 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS 0 0.29
Category members GO Category GO:0000151 ubiquitin ligase complex Database 0.24
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members GO Category GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process Database 0.23
Category members GO Category GO:0019005 SCF ubiquitin ligase complex Database 0.09
Category members GO Category GO:0016567 protein ubiquitination Database 0.07
Category members GO Category GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process Database 0.05
Category members GO Category GO:0042752 regulation of circadian rhythm Database 0
Category members GO Category GO:0043153 entrainment of circadian clock by photoperiod Database 0
Category members GO Category GO:0048511 rhythmic process Database 0


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