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Query: USP11

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
USP11 0 2.558 0.840 -0.200 -0.333 0.001 0.704

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
USP11 Phosphorylation S733 0.908 0.540 _TTS(ph)PEEVHAQPYIAIDWEPEMK_
USP11 Ubiquitylation K835 0.273 0.465 _FSYTK(gl)FSR_
USP11 Ubiquitylation K776 -0.145 0.017 _HDCVGYVM(ox)KK(gl)_
USP11 Ubiquitylation K245 -0.175 -0.284 _LWAK(gl)NSEGSLDR_
USP11 Ubiquitylation K385 -0.348 _SIVPHVFKNK(gl)_

Background Information for USP11:





Protein-protein Interactions for USP11

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ANAPC13 Cat. description Hein, Mann, Cell 2015
Category members IP bait CUL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPD Cat. description Hein, Mann, Cell 2015
Category members IP bait LRP8 Cat. description Hein, Mann, Cell 2015
Category members IP bait MZT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PCBP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait RAPGEF2 Cat. description Hein, Mann, Cell 2015
Category members IP bait SORT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TCEAL4 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMEM109 Cat. description Hein, Mann, Cell 2015
Category members IP bait USP11 Cat. description Hein, Mann, Cell 2015
Category members IP bait C14orf179 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MIER2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TCEAL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRUB1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VGLL4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in USP11

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ubiquitin-rel_dom IPR029071 1.79
Category members UCH/PAN2 IPR028889 0.62
Category members Peptidase_C19_UCH IPR001394 0.53
Category members Pept_C19_DUSP IPR006615 0.23


Protein complexes (CORUM database) featuring USP11

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring USP11

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0006511 ubiquitin-dependent protein catabolic process Database 3.57
Category members GO Category GO:0004843 ubiquitin-specific protease activity Database 3.28
Category members GO Category GO:0004221 ubiquitin thiolesterase activity Database 1.36
Category members GO Category GO:0016579 protein deubiquitination Database 1.32
Category members Pathway Pathway_742 REACTOME_PROTEIN_FOLDING 0 0.9
Category members GO Category GO:0004197 cysteine-type endopeptidase activity Database 0.38
Category members Pathway Pathway_741 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS 0 0.29
Category members GO Category GO:0008234 cysteine-type peptidase activity Database 0


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