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Query: AP3M1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
AP3M1 1 -2.249 2.120 -1.010 -0.529 -0.213 -0.553

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
AP3M1 Ubiquitylation K413 -0.636 -0.807 _AGK(gl)FQVR_
AP3M1 Ubiquitylation K283 -0.147 _HSISFK(gl)ENSSCGR_

Background Information for AP3M1:


Pubmed-AP3M1 »
Uniprot-AP3M1 »
Biogrid-AP3M1 »
ProteomicsDB-AP3M1 »

Tumorportal-AP3M1 »
COSMIC-AP3M1 »
GenomeRNAi-AP3M1 »
Genecards-AP3M1


Protein-protein Interactions for AP3M1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CHMP4C Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF11 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait RAP1B Cat. description Hein, Mann, Cell 2015
Category members IP bait UFL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait USO1 Cat. description Hein, Mann, Cell 2015
Category members IP bait VCL Cat. description Hein, Mann, Cell 2015
Category members IP bait AP3M1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait AP3S1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CAMKV Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD79B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DTNBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EDA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EIF2C3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EPHA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HLA-DMB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IDS Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PALM2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PIP4K2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RNF19B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RTDR1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM63A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VASN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VTI1B Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in AP3M1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Longin-like_dom IPR011012 0.34
Category members AP_mu_sigma_su IPR022775 0.25
Category members Clathrin_mu_C IPR008968 0.02
Category members Clathrin_mu IPR001392 0
Category members MHD IPR028565 0


Protein complexes (CORUM database) featuring AP3M1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 59 AP3 adapter complex Database 0.58
Category members Corum 652 AP3-BLOC1 complex Database 0


Categories featuring AP3M1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0006886 intracellular protein transport Database 2.48
Category members GO Category GO:0016192 vesicle-mediated transport Database 1.1
Category members Pathway Pathway_742 REACTOME_PROTEIN_FOLDING 0 0.9
Category members GO Category GO:0005765 lysosomal membrane Database 0.82
Category members GO Category GO:0030659 cytoplasmic vesicle membrane Database 0.62
Category members Pathway Pathway_741 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS 0 0.29
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0030131 clathrin adaptor complex Database 0.11
Category members GO Category GO:0006622 protein targeting to lysosome Database 0.02
Category members Pathway Pathway_74 KEGG_LYSOSOME 0 0
Category members GO Category GO:0005764 lysosome Database 0
Category members GO Category GO:0006810 transport Database 0
Category members GO Category GO:0008089 anterograde axon cargo transport Database 0
Category members GO Category GO:0048490 anterograde synaptic vesicle transport Database 0


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