bioLOGIC-db

bioLOGIC Data

Query: FBXW8

[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:
Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen

Gene name	Point score	Z-score sums	RNAi high	RNAi low	RNAPII-IP (PI)	CSB-IP	CSB-IP (PI)	Chrom.	Chrom. (PI)
FBXW8	1	-0.351	2.140	-1.050		-0.439	0.088

PTM Sites:
Back to Protein Results | Red/green: hit at lower/upper end of the respective screen

Gene name	PTM type	PTM site	UV	UV (PI)	Sequence

ProteomicsDB-FBXW8 »

Protein-protein Interactions for FBXW8

Show screen data for	Category Name and Description	Link to cat description	Data Source
Category members	IP bait CASQ2	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait CCT3	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait CCT7	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait CETN1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait KLHL2	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait MAPK14	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait TTC29	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait ZFC3H1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait ZNF263	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait ZNF408	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait ZNF669	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015

Protein Domains in FBXW8

	Domain name	Domain Description	TC-NER relevance -log10(p-value)
Category members	WD40_repeat_dom	IPR017986	1.39
Category members	Quinonprotein_ADH-like_supfam	IPR011047	0.56
Category members	WD40_repeat	IPR001680	0.52
Category members	F-box_dom	IPR001810	0

Protein complexes (CORUM database) featuring FBXW8

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	Corum	81	Ubiquitin E3 ligase (SKP1A, FBXW8, CUL7, RBX1)	Database	0.1
Category members	Corum	1258	Ubiquitin E3 ligase (GLMN, FBXW8, SKP1A, RBX1)	Database	0

Categories featuring FBXW8

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	GO Category	GO:0005515	protein binding	Database	INF
Category members	Pathway	Pathway_621	REACTOME_ADAPTIVE_IMMUNE_SYSTEM	0	4.72
Category members	Pathway	Pathway_458	REACTOME_IMMUNE_SYSTEM	0	3
Category members	Pathway	Pathway_764	REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION	0	2.56
Category members	Pathway	Pathway_888	KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS	0	2.22
Category members	Pathway	Pathway_832	REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION	0	1.58
Category members	GO Category	GO:0060712	spongiotrophoblast layer development	Database	0.45
Category members	GO Category	GO:0048471	perinuclear region of cytoplasm	Database	0.39
Category members	GO Category	GO:0005794	Golgi apparatus	Database	0.27
Category members	GO Category	GO:0050775	positive regulation of dendrite morphogenesis	Database	0.15
Category members	GO Category	GO:0007030	Golgi organization	Database	0.13
Category members	GO Category	GO:0019005	SCF ubiquitin ligase complex	Database	0.09
Category members	GO Category	GO:0031467	Cul7-RING ubiquitin ligase complex	Database	0
Category members	GO Category	GO:0060716	labyrinthine layer blood vessel development	Database	0