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REACTOME_NUCLEAR_SIGNALING_BY_ERBB4
(Pathway_977)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
CUL1 1 0.630 -0.610 -0.314 0.662 2.069 0.342 0.118
APH1B 1 -1.760 3.070
PSEN2 1 -1.820 3.280
WWOX 1 2.850 -1.200
TAB2 0 -0.030 -0.580
PSEN1 0 0.930 -1.110
RBX1 0 0.920 -0.940 -0.015 -0.422
SKP1 0 1.470 -0.970 -1.305 -0.243 -0.093 0.054
SKP1 0 1.470 -0.970 -0.472
GFAP 0 0.930 -0.340 0.523 -5.250
YAP1 0 1.010 -0.370
NCOR1 0 -0.820 1.130 -0.827 -0.215 0.037
ADAM17 0 0.520 -0.620
NCSTN 0 -1.540 2.100 0.618 0.379
BTRC 0 -0.780 0.690 0.532 -1.791 0.313
STAT5B 0 0.670 -0.960
SH2B1 0 0.970 0.010
ERBB4 0
ERBB4 0
PSENEN 0 -0.550 0.740

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ADAM17 Phosphorylation S791 -0.594 0.152 _S(ph)FEDLTDHPVTR_
APH1B Ubiquitylation K102 -0.148 _ASEGLK(gl)SINPGETAPSMR_
BTRC Ubiquitylation K466 0.325 _IVSGAYDGKIK(gl)_
CUL1 Ubiquitylation K262 0.119 _ESTEFLQQNPVTEYMK(gl)K_
CUL1 Ubiquitylation K263 0.119 -0.055 _ESTEFLQQNPVTEYMK(gl)K_
CUL1 Ubiquitylation K410 0.250 0.326 _FINNNAVTK(gl)MAQSSSK_
CUL1 Ubiquitylation K417 0.761 _MAQSSSK(gl)SPELLAR_
CUL1 Ubiquitylation K468 1.237 _FYAK(gl)MLAK_
CUL1 Ubiquitylation K503 0.665 _QACGFEYTSK(gl)LQR_
CUL1 Ubiquitylation K769 0.292 _VDGEK(gl)DTYSYLA_
ERBB4 Ubiquitylation K714 0.078 _ILK(gl)ETELKR_
ERBB4 Ubiquitylation K745 -0.474 0.342 _GIWVPEGETVK(gl)IPVAIK_
ERBB4 Ubiquitylation K854 -0.859 _NVLVK(gl)SPNHVK_
NCOR1 Phosphorylation S1195 -0.029 0.716 _MPIEDS(ph)SPEKGREEAASK_
NCOR1 Phosphorylation S1196 0.087 0.141 _MPIEDSS(ph)PEKGR_
NCOR1 Phosphorylation S1472 0.700 0.536 _AQLS(ph)PGIYDDTSAR_
NCOR1 Phosphorylation S1977 -0.959 -0.974 _YETPSDAIEVIS(ph)PASSPAPPQEK_
NCOR1 Ubiquitylation K1998 -2.086 _LQTYQPEVVK(gl)ANQAENDPTR_
NCOR1 Phosphorylation S2120 0.148 0.154 _VS(ph)PENLVDK_
NCOR1 Phosphorylation S2151 -1.006 -0.922 _SHVSSEPYEPIS(ph)PPQVPVVHEK_
NCOR1 Phosphorylation S2184 0.120 0.226 _S(ph)PGSISYLPSFFTK_
NCOR1 Phosphorylation S2187 0.396 _SPGS(ph)ISYLPSFFTK_
NCSTN Ubiquitylation K110 1.107 _DLMEK(gl)LK_
PSEN1 Phosphorylation S313 0.844 _VSKNS(ph)KYNAESTER_
PSEN1 Ubiquitylation K314 0.016 0.414 _NSK(gl)YNAESTER_
PSEN1 Phosphorylation S366 -0.340 0.055 _AAVQELSS(ph)SILAGEDPEER_
PSEN1 Phosphorylation S367 0.005 0.066 _AAVQELSSS(ph)ILAGEDPEER_
PSEN2 Phosphorylation S58 -0.112 -0.130 _TSLM(ox)SAES(ph)PTPR_
PSENEN Ubiquitylation K11 0.476 _VSNEEK(gl)LNLCR_
RBX1 Phosphorylation T9 -0.553 _(ac)AAAMDVDT(ph)PSGTNSGAGK_
RBX1 Ubiquitylation K19 -0.376 -0.371 _(ac)AAAMDVDTPSGTNSGAGK(gl)KR_
RBX1 Ubiquitylation K20 -0.541 -0.371 _(ac)AAAMDVDTPSGTNSGAGKK(gl)R_
SH2B1 Phosphorylation S96 0.112 -0.143 _ASGSLSPPILAPLS(ph)PGAEISPHDLSLESCR_
SH2B1 Phosphorylation S125 0.018 0.257 _S(ph)SEDLAGPLPSSVSSSSTTSSKPK_
SH2B1 Phosphorylation S126 0.018 0.257 _S(ph)SEDLAGPLPSSVSSSSTTSSKPK_
SKP1 Ubiquitylation K130 0.138 0.140 _GK(gl)TPEEIRK_
SKP1 Phosphorylation T131 -0.024 -0.138 _GKT(ph)PEEIRK_
SKP1 Ubiquitylation K142 0.165 0.894 _TFNIK(gl)NDFTEEEEAQVRK_
SKP1 Ubiquitylation K155 -0.096 0.069 _K(gl)ENQWCEEK_
SKP1 Ubiquitylation K163 0.109 -0.020 _ENQWCEEK(gl)_
STAT5B Phosphorylation S194 0.270 _IQAQFGPLAQLS(ph)PQER_
TAB2 Phosphorylation S580 -0.075 _S(ph)NSISQIPSLEEMQQLR_
TAB2 Phosphorylation S582 0.331 _SNS(ph)ISQIPSLEEMQQLR_
TAB2 Ubiquitylation K653 -0.519 -0.200 _SIIK(gl)TPK_
WWOX Ubiquitylation K100 -1.048 -0.703 _LAFTVDDNPTK(gl)PTTR_
YAP1 Phosphorylation S61 -0.064 0.017 _GDS(ph)ETDLEALFNAVMNPK_
YAP1 Phosphorylation T63 -0.159 -0.257 _GDSET(ph)DLEALFNAVM(ox)NPK_
YAP1 Phosphorylation T110 0.467 _QAST(ph)DAGTAGALTPQHVR_
YAP1 Phosphorylation S127 -1.544 _AHS(ph)SPASLQLGAVSPGTLTPTGVVSGPAATPTAQHLR_
YAP1 Phosphorylation S131 -1.256 -1.096 _AHSSPAS(ph)LQLGAVSPGTLTPTGVVSGPAATPTAQHLR_
YAP1 Ubiquitylation K315 -0.002 _LQQLQMEK(gl)ER_
YAP1 Ubiquitylation K321 -1.043 _LK(gl)QQELLR_
YAP1 Ubiquitylation K342 -0.589 _NINPSTANSPK(gl)CQELALR_
YAP1 Phosphorylation S367 0.272 _SQLPTLEQDGGTQNPVSS(ph)PGMSQELR_
YAP1 Phosphorylation S397 -0.200 _DES(ph)TDSGLSM(ox)SSYSVPR_


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