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Query: YAP1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
YAP1 0 0.401 1.010 -0.370

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
YAP1 Phosphorylation T110 0.467 _QAST(ph)DAGTAGALTPQHVR_
YAP1 Phosphorylation S367 0.272 _SQLPTLEQDGGTQNPVSS(ph)PGMSQELR_
YAP1 Phosphorylation S61 -0.064 0.017 _GDS(ph)ETDLEALFNAVMNPK_
YAP1 Phosphorylation T63 -0.159 -0.257 _GDSET(ph)DLEALFNAVM(ox)NPK_
YAP1 Phosphorylation S131 -1.256 -1.096 _AHSSPAS(ph)LQLGAVSPGTLTPTGVVSGPAATPTAQHLR_
YAP1 Phosphorylation S127 -1.544 _AHS(ph)SPASLQLGAVSPGTLTPTGVVSGPAATPTAQHLR_
YAP1 Ubiquitylation K315 -0.002 _LQQLQMEK(gl)ER_
YAP1 Ubiquitylation K321 -1.043 _LK(gl)QQELLR_
YAP1 Ubiquitylation K342 -0.589 _NINPSTANSPK(gl)CQELALR_
YAP1 Phosphorylation S397 -0.200 _DES(ph)TDSGLSM(ox)SSYSVPR_

Background Information for YAP1:


Pubmed-YAP1 »
Uniprot-YAP1 »
Biogrid-YAP1 »
ProteomicsDB-YAP1 »

Tumorportal-YAP1 »
COSMIC-YAP1 »
GenomeRNAi-YAP1 »
Genecards-YAP1


Protein-protein Interactions for YAP1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AMOT Cat. description Hein, Mann, Cell 2015
Category members IP bait LIN7C Cat. description Hein, Mann, Cell 2015
Category members IP bait YAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ARRDC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BAG4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BTRC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C18orf1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CYYR1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DEFA6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MPP5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRRG4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PTPN14 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TEAD2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TEAD4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in YAP1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WW_dom IPR001202 1.15


Protein complexes (CORUM database) featuring YAP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring YAP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members GO Category GO:0003713 transcription coactivator activity Database 3.68
Category members GO Category GO:0006974 cellular response to DNA damage stimulus Database 3.57
Category members GO Category GO:0006366 transcription from RNA polymerase II promoter Database 0.96
Category members Pathway Pathway_90 REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION 0 0.88
Category members GO Category GO:0035329 hippo signaling Database 0.68
Category members Pathway Pathway_1013 REACTOME_SIGNALING_BY_HIPPO 0 0.63
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members Pathway Pathway_933 PID_TGFBR_PATHWAY 0 0.52
Category members GO Category GO:0006367 transcription initiation from RNA polymerase II promoter Database 0.25
Category members Pathway Pathway_1 REACTOME_FATTY_ACID_TRIACYLGLYCEROL_AND_KETONE_BODY_METABOLISM 0 0.23
Category members GO Category GO:0005667 transcription factor complex Database 0.19
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members Pathway Pathway_200 PID_P73PATHWAY 0 0.11
Category members GO Category GO:0048339 paraxial mesoderm development Database 0.09
Category members Pathway Pathway_822 REACTOME_GENERIC_TRANSCRIPTION_PATHWAY 0 0.09
Category members GO Category GO:0008283 cell proliferation Database 0.06
Category members GO Category GO:0042127 regulation of cell proliferation Database 0.06
Category members Pathway Pathway_545 REACTOME_SIGNALING_BY_ERBB4 0 0.05
Category members GO Category GO:0070064 proline-rich region binding Database 0.01
Category members GO Category GO:0044212 transcription regulatory region DNA binding Database 0
Category members Pathway Pathway_209 PID_DELTA_NP63_PATHWAY 0 0
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members Pathway Pathway_609 PID_ERBB4_PATHWAY 0 0
Category members Pathway Pathway_939 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION 0 0
Category members Pathway Pathway_977 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 0 0
Category members GO Category GO:0001076 RNA polymerase II transcription factor binding transcription factor activity Database 0
Category members GO Category GO:0001570 vasculogenesis Database 0
Category members GO Category GO:0003143 embryonic heart tube morphogenesis Database 0
Category members GO Category GO:0003714 transcription corepressor activity Database 0
Category members GO Category GO:0008284 positive regulation of cell proliferation Database 0
Category members GO Category GO:0010837 regulation of keratinocyte proliferation Database 0
Category members GO Category GO:0030216 keratinocyte differentiation Database 0
Category members GO Category GO:0030857 negative regulation of epithelial cell differentiation Database 0
Category members GO Category GO:0030903 notochord development Database 0
Category members GO Category GO:0035019 somatic stem cell maintenance Database 0
Category members GO Category GO:0046622 positive regulation of organ growth Database 0
Category members GO Category GO:0048368 lateral mesoderm development Database 0
Category members GO Category GO:0060242 contact inhibition Database 0


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