RNAi screen result	RNAPII IP (MG132)	CSB IP	CSB IP (MG132)	Chrom.	Chrom. (MG132)	Ubi /Phospo	Ubi /Phospho (MG132)
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Gene name	MGoogle Score	RNAi high	RNAi low	RNAPII-IP (MG132)	CSB-IP	CSB-IP (MG132)	Chrom.	Chrom. (MG132)
JUN	3	-0.930	0.930			-0.126
AKT3	2	0.580	-0.030	-0.194
AKT3	2	0.580	-0.030
TCEB2	1	-1.490	2.890	-0.134	-0.585	0.682	0.156	0.662
PIK3R2	1	2.740	-1.180				0.269	0.348
CUL2	1	-1.790	3.760	-0.293	0.044	0.860	-0.146	0.162
CUL2	1	-1.790	3.760
RAF1	1	2.020	-1.230
KRAS	1	-0.510	0.620				1.031	0.887
KRAS	1	-0.510	0.620				0.246	-0.346
ETS1	1	1.070	-0.650
MAP2K1	1	-1.590	2.780
NRAS	1	1.810	-0.720				0.246	-0.346
CREBBP	0	0.840	-0.950				-3.889	-1.071
PIK3CB	0	-1.390	2.350
PIK3CB	0	-0.710	1.450
CDC42	0	-0.170	0.490	-0.597			-1.527	-1.013
CDC42	0	1.240	-0.940	-0.597			-1.527	-1.013
ARAF	0	0.550	-0.670
ARAF	0	0.550	-0.670
FH	0	1.300	-0.210				1.313	0.652
CRKL	0	0.290	-0.620
RBX1	0	0.920	-0.940	-0.015			-0.422
EP300	0	-1.210	1.320	-1.089			-1.694	-0.723
HIF1A	0	-0.480	0.400
MAPK3	0
AKT2	0	-1.420	2.210	-0.194
TGFB1	0	-0.550	1.050
MET	0	-0.010	-0.330
RAPGEF1	0	1.620	-0.780
GAB1	0	1.950	-1.110
SOS1	0	0.500	-0.620	-0.570
SLC2A1	0	0.090	-0.210				-0.169	-0.253
PIK3R3	0	-0.140	-0.480
PIK3R3	0	-0.140	-0.480				-0.441	0.147
TGFB3	0	0.900	-0.540
PIK3CA	0
MAP2K2	0	-0.610	0.080
MAP2K2	0	-0.610	0.080
RAP1B	0	-0.520	0.540	-0.200			0.374	0.556
EGLN3	0	-1.310	1.790
PAK4	0	-0.700	0.980				0.206	-0.937
EGLN1	0	0.180	-0.270	-1.041
RAC1	0	-0.580	1.580	0.486			-0.364	-0.568
AKT1	0	-0.050	0.700
AKT1	0	0.860	-0.040
ARNT	0	1.120	-0.500
PIK3R1	0	1.910	-1.220				-0.441	0.147
PAK1	0	1.190	-0.630
TCEB1	0	0.480	-0.460	0.004			-1.523	0.284
FLCN	0	1.070	-0.810
BRAF	0
CRK	0	-0.790	0.230
HRAS	0	1.470	-0.520
GRB2	0	-0.240	0.300		-1.021	0.057	0.906
PTPN11	0	-0.210	-0.400	0.644			1.053	0.451
PAK2	0	-0.760	1.040

Gene name	PTM type	PTM site	UV	UV (MG132)	Sequence
AKT1	Phosphorylation	S124	0.252	0.311	_SGS(ph)PSDNSGAEEMEVSLAKPK_
AKT1	Phosphorylation	S126	-0.241		_SGSPS(ph)DNSGAEEM(ox)EVSLAK_
AKT1	Ubiquitylation	K301	0.988		_EGIK(gl)DGATMK_
AKT2	Ubiquitylation	K14	0.306	0.070	_EGWLHK(gl)R_
AKT2	Ubiquitylation	K111	1.082		_AIQMVANSLK(gl)QR_
AKT2	Ubiquitylation	K160		0.251	_LLGK(gl)GTFGK_
AKT2	Phosphorylation	T451	-0.091	-0.612	_YFDDEFTAQSITIT(ph)PPDRYDSLGLLELDQR_
AKT2	Phosphorylation	Y456		-0.265	_YFDDEFTAQSITITPPDRY(ph)DSLGLLELDQR_
AKT3	Ubiquitylation	K14	0.306	0.070	_EGWLHK(gl)R_
AKT3	Ubiquitylation	K14	4.941	5.277	_EGWVQK(gl)R_
AKT3	Ubiquitylation	K111	1.082		_AIQMVANSLK(gl)QR_
AKT3	Phosphorylation	S120		1.097	_MNCS(ph)PTSQIDNIGEEEMDASTTHHK_
AKT3	Ubiquitylation	K160		0.251	_LLGK(gl)GTFGK_
AKT3	Phosphorylation	T451	-0.091	-0.612	_YFDDEFTAQSITIT(ph)PPDRYDSLGLLELDQR_
AKT3	Phosphorylation	Y456		-0.265	_YFDDEFTAQSITITPPDRY(ph)DSLGLLELDQR_
ARAF	Phosphorylation	T227		0.017	_STSTPNVHMVSTT(ph)APMDSNLIQLTGQSFSTDAAGSR_
ARAF	Phosphorylation	S260	0.245		_GS(ph)PSPASVSSGR_
ARAF	Ubiquitylation	K543	-1.068	-0.962	_ISSNCPK(gl)AMR_
ARAF	Phosphorylation	S621	0.212	0.271	_SAS(ph)EPSLHR_
ARNT	Phosphorylation	S81		1.133	_FARS(ph)DDEQSSADKER_
ARNT	Ubiquitylation	K421		-2.502	_DSFQQVVK(gl)LK_
BRAF	Phosphorylation	S151	-0.685	-0.629	_SNPKS(ph)PQKPIVR_
BRAF	Phosphorylation	S363	-0.023	-0.241	_S(ph)SSAPNVHINTIEPVNIDDLIR_
BRAF	Phosphorylation	S365	-0.286	0.012	_SSS(ph)APNVHINTIEPVNIDDLIR_
BRAF	Phosphorylation	S399	-0.890	-0.527	_GDGGSTTGLS(ph)ATPPASLPGSLTNVK_
BRAF	Phosphorylation	T401	-0.525		_GDGGSTTGLSAT(ph)PPASLPGSLTNVK_
BRAF	Phosphorylation	S446	0.246	0.349	_RDS(ph)SDDWEIPDGQITVGQR_
BRAF	Phosphorylation	S447	0.579	0.623	_RDSS(ph)DDWEIPDGQITVGQR_
BRAF	Phosphorylation	S729	0.208	0.219	_SAS(ph)EPSLNR_
CDC42	Ubiquitylation	K173	-1.839		_DDPSTIEK(gl)LAK_
CDC42	Ubiquitylation	K178	-0.801	-0.716	_NK(gl)QKPITPETAEK_
CDC42	Ubiquitylation	K180	-1.806		_QK(gl)PITPETAEK(gl)LAR_
CDC42	Ubiquitylation	K189	-1.082		_QKPITPETAEK(gl)LAR_
CDC42	Ubiquitylation	K198	0.550	1.159	_AVK(gl)YVECSALTQK_
CDC42	Ubiquitylation	K208	-0.937	0.038	_YVECSALTQK(gl)GLK_
CDC42	Ubiquitylation	K228	-2.488		_NVFDEAILAALEPPEPK(gl)K_
CDC42	Ubiquitylation	K229	-1.254		_NVFDEAILAALEPPEPKK(gl)_
CREBBP	Phosphorylation	S2093	0.037	0.097	_SIS(ph)PSALQDLLR_
CRK	Phosphorylation	S40	0.533	0.363	_DS(ph)STSPGDYVLSVSENSR_
CRK	Phosphorylation	S41	1.065	0.801	_DSS(ph)TSPGDYVLSVSENSR_
CRKL	Phosphorylation	S41		0.868	_DS(ph)STCPGDYVLSVSENSR_
CRKL	Phosphorylation	S107	-0.818	-1.177	_YPS(ph)PPMGSVSAPNLPTAEDNLEYVR_
CUL2	Ubiquitylation	K35	1.454		_VVDFDETWNK(gl)LLTTIK_
CUL2	Ubiquitylation	K257	0.023		_QEASNLLQESNCSQYMEK(gl)VLGR_
CUL2	Ubiquitylation	K401	0.064	-0.162	_ALTSVVNYREPK(gl)SVCK_
CUL2	Ubiquitylation	K423	-0.295		_SAK(gl)GMTENEVEDR_
EGLN1	Phosphorylation	S12	-1.100	-0.639	_(ac)ANDSGGPGGPS(ph)PSER_
EGLN1	Phosphorylation	S125	-1.027	-0.755	_AKPPADPAAAAS(ph)PCR_
EGLN3	Ubiquitylation	K48		-0.501	_VK(gl)QLHCTGALR_
EGLN3	Ubiquitylation	K111		-0.831	_LGK(gl)YYVK_
EP300	Phosphorylation	S1038	-0.672	-0.349	_TEIKEEEDQPSTSATQSS(ph)PAPGQSK_
EP300	Phosphorylation	S1726	0.994	0.627	_LGLGLDDESNNQQAAATQS(ph)PGDSRR_
EP300	Phosphorylation	S2328	-1.092	0.725	_PQSQPPHSSPS(ph)PR_
ETS1	Ubiquitylation	K416		7.479	_MNYEK(gl)LSR_
ETS1	Ubiquitylation	K427		-0.895	_YYYDK(gl)NIIHK_
FLCN	Phosphorylation	S62	-0.873	-0.905	_AHS(ph)PAEGASVESSSPGPK_
GAB1	Phosphorylation	S266	0.756	0.551	_SYS(ph)HDVLPK_
GAB1	Phosphorylation	S367	0.230	0.176	_TAS(ph)DTDSSYCIPTAGMS(ph)PSR_
GAB1	Phosphorylation	T369		-0.352	_TASDT(ph)DSSYCIPTAGMS(ph)PSR_
GAB1	Phosphorylation	S381	-0.481	0.139	_TASDTDSSYCIPTAGM(ox)S(ph)PSR_
GAB1	Phosphorylation	S401	0.266	0.788	_DAS(ph)SQDCYDIPR_
GAB1	Phosphorylation	S402	0.328	0.633	_DASS(ph)QDCYDIPR_
GAB1	Phosphorylation	S419		0.540	_SSS(ph)LEGFHNHFK_
GRB2	Ubiquitylation	K10	0.146		_YDFK(gl)ATADDELSFK_
GRB2	Ubiquitylation	K20	-0.078		_ATADDELSFK(gl)R_
GRB2	Ubiquitylation	K69	-0.362	0.641	_AK(gl)AEEMLSK_
GRB2	Ubiquitylation	K76	0.754		_AEEMLSK(gl)QR_
GRB2	Ubiquitylation	K109	0.381	-0.002	_FGNDVQHFK(gl)VLR_
HIF1A	Ubiquitylation	K10		-1.686	_(ac)MEGAGGANDK(gl)K_
HIF1A	Ubiquitylation	K11		-1.686	_(ac)MEGAGGANDK(gl)K_
HIF1A	Ubiquitylation	K173		-0.662	_MK(gl)CTLTSR_
HIF1A	Ubiquitylation	K186		-0.590	_TMNIK(gl)SATWK_
HIF1A	Ubiquitylation	K252		-0.784	_HSLDM(ox)K(gl)FSYCDER_
HIF1A	Ubiquitylation	K371		-0.508	_PVESSDMK(gl)MTQLFTK_
HIF1A	Ubiquitylation	K378		-0.077	_MTQLFTK(gl)VESEDTSSLFDK_
HIF1A	Ubiquitylation	K390		-0.348	_VESEDTSSLFDK(gl)LKK_
HIF1A	Ubiquitylation	K392		-0.546	_VESEDTSSLFDKLK(gl)_
HIF1A	Ubiquitylation	K393		-0.451	_VESEDTSSLFDKLKK(gl)_
HIF1A	Ubiquitylation	K710		-1.696	_TTVPEEELNPK(gl)ILALQNAQR_
HRAS	Ubiquitylation	K170	-1.005		_K(gl)LNPPDESGPGCMSCK_
JUN	Phosphorylation	S58	-0.167	-1.247	_AKNS(ph)DLLTSPDVGLLK_
JUN	Phosphorylation	T62	2.545	1.674	_NSDLLT(ph)SPDVGLLK_
JUN	Phosphorylation	S63	2.030	1.458	_NSDLLTS(ph)PDVGLLK_
JUN	Ubiquitylation	K70	9.213		_NSDLLTSPDVGLLK(gl)_
JUN	Phosphorylation	S73	1.499	0.845	_LAS(ph)PELER_
JUN	Phosphorylation	S243	-0.642	-1.399	_LQALKEEPQTVPEMPGETPPLS(ph)PIDMESQER_
JUN	Ubiquitylation	K309	1.034	0.155	_EQVAQLK(gl)QK_
KRAS	Ubiquitylation	K128	1.528	1.433	_TVDTK(gl)QAHELAK_
KRAS	Ubiquitylation	K235	0.591	0.087	_TVDTK(gl)QAQDLAR_
KRAS	Ubiquitylation	K254	-0.450	-0.156	_SYGIPFIETSAK(gl)TR_
MAP2K1	Ubiquitylation	K192	-0.205	-0.241	_DVK(gl)PSNILVNSR_
MAP2K1	Phosphorylation	S385		0.066	_RSDAEEVDFAGWLCSTIGLNQPS(ph)TPTHAAGV_
MAP2K1	Phosphorylation	T386		0.377	_RSDAEEVDFAGWLCSTIGLNQPST(ph)PTHAAGV_
MAP2K2	Phosphorylation	S23	0.873	0.258	_RKPVLPALTINPTIAEGPS(ph)PTSEGASEANLVDLQK_
MAP2K2	Phosphorylation	T25		0.439	_RKPVLPALTINPTIAEGPSPT(ph)SEGASEANLVDLQK_
MAP2K2	Ubiquitylation	K192	-0.205	-0.241	_DVK(gl)PSNILVNSR_
MAP2K2	Phosphorylation	S293		-0.361	_ELEAIFGRPVVDGEEGEPHS(ph)ISPR_
MAP2K2	Phosphorylation	S295	-0.234	0.026	_ELEAIFGRPVVDGEEGEPHSIS(ph)PR_
MAP2K2	Phosphorylation	T394	0.570	0.158	_LNQPGT(ph)PTR_
MAPK3	Phosphorylation	Y204	-0.807	-2.487	_IADPEHDHTGFLTEY(ph)VATR_
MAPK3	Ubiquitylation	K289		-0.608	_NYLQSLPSKTK(gl)_
MET	Ubiquitylation	K962	0.146		_QIK(gl)DLGSELVR_
MET	Phosphorylation	S988	0.064		_S(ph)VSPTTEM(ox)VSNESVDYR_
MET	Phosphorylation	S990	0.192	-0.105	_SVS(ph)PTTEM(ox)VSNESVDYR_
MET	Phosphorylation	T992	0.501	-0.048	_SVSPT(ph)TEMVSNESVDYR_
MET	Phosphorylation	S997		0.285	_S(ph)VSPTTEMVS(ph)NESVDYR_
NRAS	Ubiquitylation	K128	1.528	1.433	_TVDTK(gl)QAHELAK_
PAK1	Phosphorylation	S174	-1.439	-0.597	_AVSETPAVPPVS(ph)EDEDDDDDDATPPPVIAPRPEHTK_
PAK1	Phosphorylation	T212		0.312	_SVIEPLPVT(ph)PTR_
PAK1	Phosphorylation	T219	-0.560	-0.962	_DVAT(ph)SPISPTENNTT(ph)PPDALTR_
PAK1	Phosphorylation	S220	-0.916	-0.774	_DVATS(ph)PISPTENNTTPPDALTR_
PAK1	Phosphorylation	S223	1.033	0.153	_DVATSPIS(ph)PTENNTTPPDALTR_
PAK1	Phosphorylation	T225	-1.278		_DVATSPISPT(ph)ENNTTPPDALTR_
PAK1	Phosphorylation	T230	-1.418	-1.502	_DVATSPISPTENNTT(ph)PPDALTR_
PAK2	Phosphorylation	S2	-1.228	-0.902	_(ac)S(ph)DNGELEDKPPAPPVR_
PAK2	Ubiquitylation	K136	1.213		_FYDSNTVK(gl)QK_
PAK2	Phosphorylation	S141	-0.294	-0.321	_YLS(ph)FTPPEK_
PAK2	Ubiquitylation	K370	-0.565		_DIK(gl)SDNVLLGMEGSVK_
PAK4	Phosphorylation	S104	-0.563	-0.422	_RDS(ph)PPPPAR_
PAK4	Phosphorylation	S181	-0.528	-0.724	_DKRPLS(ph)GPDVGTPQPAGLASGAK_
PAK4	Phosphorylation	T207	-0.287	-0.118	_LAAGRPFNT(ph)YPR_
PAK4	Phosphorylation	S291		-3.268	_GAPSPGVLGPHASEPQLAPPACTPAAPAVPGPPGPRS(ph)PQREPQR_
PAK4	Phosphorylation	S474	-0.003	0.050	_S(ph)LVGTPYWMAPELISR_
PAK4	Phosphorylation	T478	0.024		_RKSLVGT(ph)PYWM(ox)APELISR_
PIK3CA	Ubiquitylation	K864	0.390	0.588	_NSHTIM(ox)QIQCK(gl)GGLK_
PIK3CA	Ubiquitylation	K868	0.204	0.651	_NSHTIM(ox)QIQCKGGLK(gl)_
PIK3CA	Ubiquitylation	K974	-0.273		_GAQECTK(gl)TREFER_
PIK3CB	Ubiquitylation	K1044		0.990	_SEEEALKQFKQK(gl)_
PIK3R2	Phosphorylation	S262		-2.237	_APPPPS(ph)SPPPGGAPDGSEPSPDFPALLVEK_
PIK3R2	Phosphorylation	S263		-2.237	_APPPPS(ph)SPPPGGAPDGSEPSPDFPALLVEK_
PIK3R2	Ubiquitylation	K500	-0.189		_IFEEQGQTQEK(gl)CSK_
PIK3R2	Ubiquitylation	K541	-0.609		_TK(gl)LEQQLR_
PIK3R2	Ubiquitylation	K564	-0.431	-1.022	_MNSLK(gl)PDLMQLR_
PIK3R3	Ubiquitylation	K226		-0.376	_YQQDQLVKEDNIDAVGKK(gl)_
PIK3R3	Ubiquitylation	K320		0.385	_LGEIHDSK(gl)MR_
PTPN11	Ubiquitylation	K124	0.562		_EAEK(gl)LLTEK_
RAC1	Ubiquitylation	K115	-1.745	-0.215	_AK(gl)WYPEVR_
RAC1	Ubiquitylation	K142	0.492		_LDLRDDK(gl)DTIEK_
RAC1	Ubiquitylation	K152	0.099	-0.292	_K(gl)LTPITYPQGLAMAK_
RAC1	Ubiquitylation	K166	-0.981	-0.655	_LTPITYPQGLAMAK(gl)EIGAVK_
RAC1	Ubiquitylation	K172	1.026	0.412	_EIGAVK(gl)YLECSALTQR_
RAC1	Ubiquitylation	K185	-0.113	0.578	_GLK(gl)TVFDEAIR_
RAC1	Ubiquitylation	K202	-1.379	-1.447	_AVLCPPPVK(gl)KR_
RAC1	Ubiquitylation	K203	-1.708	-1.447	_AVLCPPPVKK(gl)_
RAF1	Phosphorylation	S29	0.028	-0.571	_DAVFDGSSCIS(ph)PTIVQQFGYQR_
RAF1	Phosphorylation	T31	0.028	-0.669	_DAVFDGSSCIS(ph)PTIVQQFGYQR_
RAF1	Phosphorylation	S244		0.053	_YSTPHAFTFNTSS(ph)PSSEGSLSQR_
RAF1	Phosphorylation	S259	-0.069	0.054	_STS(ph)TPNVHM(ox)VSTTLPVDSR_
RAF1	Phosphorylation	S301		-0.651	_SHSESASPSALSSSPNNLS(ph)PTGWSQPK_
RAF1	Phosphorylation	T303		-0.664	_SHSESASPSALSSSPNNLSPT(ph)GWSQPK_
RAF1	Phosphorylation	S497		-0.449	_SRWS(ph)GSQQVEQPTGSVLWMAPEVIR_
RAF1	Phosphorylation	S621	0.212	0.271	_SAS(ph)EPSLHR_
RAF1	Phosphorylation	S642	-0.197	0.463	_AAHTEDINACTLTTS(ph)PR_
RAP1B	Ubiquitylation	K174	0.197		_KTPVPGK(gl)AR_
RAPGEF1	Phosphorylation	S377		0.629	_LSKS(ph)DEQLSSLDR_
RBX1	Phosphorylation	T9		-0.553	_(ac)AAAMDVDT(ph)PSGTNSGAGK_
RBX1	Ubiquitylation	K19	-0.376	-0.371	_(ac)AAAMDVDTPSGTNSGAGK(gl)KR_
RBX1	Ubiquitylation	K20	-0.541	-0.371	_(ac)AAAMDVDTPSGTNSGAGKK(gl)R_
SLC2A1	Ubiquitylation	K270	-1.109	0.356	_GTADVTHDLQEM(ox)K(gl)EESR_
SLC2A1	Ubiquitylation	K502	-1.643		_QGGASQSDK(gl)TPEELFHPLGADSQV_
SOS1	Phosphorylation	S1082	0.278		_IPESETESTASAPNS(ph)PR_
SOS1	Phosphorylation	S1166	0.097	-0.094	_RPESAPAES(ph)SPSK_
TCEB1	Ubiquitylation	K32	0.313	0.583	_LISSDGHEFIVK(gl)R_
TCEB1	Ubiquitylation	K72	-0.158		_EIPSHVLSK(gl)_
TCEB2	Ubiquitylation	K28		-0.246	_ESSTVFELK(gl)R_
TCEB2	Ubiquitylation	K36		-1.370	_IVEGILK(gl)RPPDEQR_
TGFB1	Ubiquitylation	K50		-0.557	_GQILSK(gl)LR_
TGFB3	Ubiquitylation	K50		-0.557	_GQILSK(gl)LR_