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Query: SLC2A1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SLC2A1 0 -1.175 0.090 -0.210 -0.169 -0.253

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SLC2A1 Ubiquitylation K270 -1.109 0.356 _GTADVTHDLQEM(ox)K(gl)EESR_
SLC2A1 Ubiquitylation K502 -1.643 _QGGASQSDK(gl)TPEELFHPLGADSQV_

Background Information for SLC2A1:


Pubmed-SLC2A1 »
Uniprot-SLC2A1 »
Biogrid-SLC2A1 »
ProteomicsDB-SLC2A1 »

Tumorportal-SLC2A1 »
COSMIC-SLC2A1 »
GenomeRNAi-SLC2A1 »
Genecards-SLC2A1


Protein-protein Interactions for SLC2A1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BMPR1A Cat. description Hein, Mann, Cell 2015
Category members IP bait CCT8 Cat. description Hein, Mann, Cell 2015
Category members IP bait NCSTN Cat. description Hein, Mann, Cell 2015
Category members IP bait NEIL3 Cat. description Hein, Mann, Cell 2015
Category members IP bait STK17B Cat. description Hein, Mann, Cell 2015
Category members IP bait TMED2 Cat. description Hein, Mann, Cell 2015


Protein Domains in SLC2A1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Sugar/inositol_transpt IPR003663 0
Category members Sub_transporter IPR005828 0
Category members MFS IPR011701 0
Category members MFS_dom_general_subst_transpt IPR016196 0
Category members MFS_dom IPR020846 0


Protein complexes (CORUM database) featuring SLC2A1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SLC2A1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0042470 melanosome Database 5.59
Category members GO Category GO:0008645 hexose transport Database 4.15
Category members Pathway Pathway_98 REACTOME_GLUCOSE_TRANSPORT 0 3.58
Category members GO Category GO:0015758 glucose transport Database 2.09
Category members GO Category GO:0005911 cell-cell junction Database 1.4
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_65 PID_MYC_ACTIV_PATHWAY 0 1.08
Category members Pathway Pathway_5 REACTOME_INTEGRATION_OF_ENERGY_METABOLISM 0 0.9
Category members GO Category GO:0006461 protein complex assembly Database 0.57
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0019900 kinase binding Database 0.45
Category members GO Category GO:0030496 midbody Database 0.39
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0005622 intracellular Database 0.32
Category members Pathway Pathway_34 REACTOME_METABOLISM_OF_CARBOHYDRATES 0 0.31
Category members GO Category GO:0006767 water-soluble vitamin metabolic process Database 0.27
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members Pathway Pathway_96 REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT 0 0.23
Category members GO Category GO:0006766 vitamin metabolic process Database 0.23
Category members Pathway Pathway_762 PID_HIF2PATHWAY 0 0.23
Category members GO Category GO:0006112 energy reserve metabolic process Database 0.21
Category members Pathway Pathway_279 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS 0 0.18
Category members GO Category GO:0055085 transmembrane transport Database 0.12
Category members Pathway Pathway_52 PID_HIF1_TFPATHWAY 0 0.11
Category members Pathway Pathway_270 REACTOME_REGULATION_OF_INSULIN_SECRETION 0 0.09
Category members Pathway Pathway_99 REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES 0 0.08
Category members GO Category GO:0055056 D-glucose transmembrane transporter activity Database 0.08
Category members GO Category GO:0005975 carbohydrate metabolic process Database 0.07
Category members GO Category GO:0043621 protein self-association Database 0.07
Category members GO Category GO:0030864 cortical actin cytoskeleton Database 0.06
Category members GO Category GO:0050796 regulation of insulin secretion Database 0.06
Category members GO Category GO:0019852 L-ascorbic acid metabolic process Database 0.04
Category members GO Category GO:0016323 basolateral plasma membrane Database 0.04
Category members Pathway Pathway_23 KEGG_RENAL_CELL_CARCINOMA 0 0.03
Category members GO Category GO:0031982 vesicle Database 0.01
Category members Pathway Pathway_1289 BIOCARTA_VITCB_PATHWAY 0 0
Category members Pathway Pathway_1305 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS 0 0
Category members Pathway Pathway_24 KEGG_PATHWAYS_IN_CANCER 0 0
Category members Pathway Pathway_40 KEGG_ADIPOCYTOKINE_SIGNALING_PATHWAY 0 0
Category members Pathway Pathway_750 REACTOME_TRANSPORT_OF_GLUCOSE_AND_OTHER_SUGARS_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS 0 0
Category members Disease phenotype Childhood_absence_epilepsy Childhood absence epilepsy Database 0
Category members Disease phenotype Paroxysmal_exertion-induced_dyskinesia Paroxysmal exertion-induced dyskinesia Database 0
Category members GO Category GO:0001939 female pronucleus Database 0
Category members GO Category GO:0005355 glucose transmembrane transporter activity Database 0
Category members GO Category GO:0005901 caveola Database 0
Category members GO Category GO:0006970 response to osmotic stress Database 0
Category members GO Category GO:0022857 transmembrane transporter activity Database 0
Category members GO Category GO:0022891 substrate-specific transmembrane transporter activity Database 0
Category members GO Category GO:0033300 dehydroascorbic acid transporter activity Database 0
Category members GO Category GO:0042149 cellular response to glucose starvation Database 0
Category members GO Category GO:0042908 xenobiotic transport Database 0
Category members GO Category GO:0070837 dehydroascorbic acid transport Database 0


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