RNAi screen result	RNAPII IP (MG132)	CSB IP	CSB IP (MG132)	Chrom.	Chrom. (MG132)	Ubi /Phospo	Ubi /Phospho (MG132)
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Gene name	MGoogle Score	RNAi high	RNAi low	RNAPII-IP (MG132)	CSB-IP	CSB-IP (MG132)	Chrom.	Chrom. (MG132)
PCK1	3	-0.250	0.020
PCK1	3	-0.250	0.020	-0.618	1.207	-2.619	1.882	1.706
PCK2	2	0.680	-0.790	-0.618	1.207	-2.619	1.882	1.706
AKT3	2	0.580	-0.030	-0.194
AKT3	2	0.580	-0.030
MAPK9	1	0.110	-0.490
TRAF2	1	-0.570	0.540
TRAF2	1	-0.570	0.540
CAMKK1	0	0.380	0.000
ADIPOR2	0	0.770	-0.900
PRKCQ	0	0.410	0.020
TNFRSF1A	0	-0.590	0.470
ACSL4	0	1.120	-0.740	-0.154		-1.054	0.236	0.117
IKBKB	0	0.400	0.610
AKT2	0	-1.420	2.210	-0.194
PRKAG2	0	1.300	-0.990	0.278			-0.667
NFKB1	0	0.720	-0.810
CAMKK2	0	1.040	-0.430
CAMKK2	0	1.040	-0.430
PRKAB1	0	0.640	-1.180
LEPR	0	-0.050	0.330
SLC2A1	0	0.090	-0.210				-0.169	-0.253
STK11	0
ACSL3	0	-1.350	2.060	0.010	0.425	-0.116	0.343	0.188
PRKAA1	0	0.910	0.060
IRS4	0	-0.240	-0.060	-0.868	-1.279	-1.308	-0.107	0.122
AKT1	0	-0.050	0.700
AKT1	0	0.860	-0.040
NFKBIE	0	1.270	-0.670
ACSL1	0	-1.550	2.430	-0.319			0.348	-0.094
ACSL1	0	-1.090	1.870	-0.319			0.348	-0.094
ADIPOR1	0	-0.720	0.740
PRKAA2	0	-0.030	-0.350
PRKAA2	0	-0.030	-0.350
ACSL6	0	-1.270	2.480	-0.319			0.348	-0.094
ACSL6	0	-0.630	0.500	-0.319			0.348	-0.094
STAT3	0	0.200	-1.270					0.334
IRS1	0
RELA	0	-1.130	1.600	0.793
PTPN11	0	-0.210	-0.400	0.644			1.053	0.451
PRKAG1	0	0.400	-0.420	0.278			-0.667
IRS2	0	-0.190	-0.130
ACSL5	0	0.430	-0.550	-0.319			0.348	-0.094
MTOR	0	-0.680	0.150	0.757			0.074	0.101
RXRB	0	-0.900	1.680					-0.559
CHUK	0			-0.480

Gene name	PTM type	PTM site	UV	UV (MG132)	Sequence
ACSL1	Ubiquitylation	K386		-0.432	_IFGQANTTLK(gl)R_
ACSL1	Ubiquitylation	K521		-2.563	_GPNVFQGYLK(gl)DPAK_
ACSL3	Ubiquitylation	K8		0.466	_(ac)MNNHVSSK(gl)PSTMK_
ACSL3	Ubiquitylation	K63	-0.973	-1.522	_AKPVNSK(gl)PDSAYR_
ACSL4	Ubiquitylation	K49	-1.745		_AK(gl)PTSDKPGSPYR_
ACSL4	Ubiquitylation	K54	-1.457		_AKPTSDK(gl)PGSPYR_
ACSL4	Ubiquitylation	K354	0.109	0.988	_IGYSSPLTLSDQSSK(gl)IK_
ACSL4	Ubiquitylation	K356	0.153	0.800	_IGYSSPLTLSDQSSKIK(gl)_
ACSL4	Ubiquitylation	K500	-1.017	-0.639	_LK(gl)DWQEGGYTINDKPNPR_
ACSL4	Ubiquitylation	K621	0.455	0.184	_SDQSYVISFVVPNQK(gl)R_
ACSL4	Ubiquitylation	K661	0.291	0.519	_EAANAM(ox)K(gl)LER_
ACSL4	Ubiquitylation	K670	-0.058	-0.343	_FEIPIK(gl)VR_
ACSL4	Ubiquitylation	K702	0.575		_NHYLK(gl)DIER_
ACSL5	Ubiquitylation	K386		-0.432	_IFGQANTTLK(gl)R_
ACSL5	Ubiquitylation	K521		-2.563	_GPNVFQGYLK(gl)DPAK_
ACSL6	Ubiquitylation	K386		-0.432	_IFGQANTTLK(gl)R_
ACSL6	Ubiquitylation	K521		-2.563	_GPNVFQGYLK(gl)DPAK_
ADIPOR1	Ubiquitylation	K137		-0.271	_ACFK(gl)SIFR_
ADIPOR2	Ubiquitylation	K137		-0.271	_ACFK(gl)SIFR_
AKT1	Phosphorylation	S124	0.252	0.311	_SGS(ph)PSDNSGAEEMEVSLAKPK_
AKT1	Phosphorylation	S126	-0.241		_SGSPS(ph)DNSGAEEM(ox)EVSLAK_
AKT1	Ubiquitylation	K301	0.988		_EGIK(gl)DGATMK_
AKT2	Ubiquitylation	K14	0.306	0.070	_EGWLHK(gl)R_
AKT2	Ubiquitylation	K111	1.082		_AIQMVANSLK(gl)QR_
AKT2	Ubiquitylation	K160		0.251	_LLGK(gl)GTFGK_
AKT2	Phosphorylation	T451	-0.091	-0.612	_YFDDEFTAQSITIT(ph)PPDRYDSLGLLELDQR_
AKT2	Phosphorylation	Y456		-0.265	_YFDDEFTAQSITITPPDRY(ph)DSLGLLELDQR_
AKT3	Ubiquitylation	K14	0.306	0.070	_EGWLHK(gl)R_
AKT3	Ubiquitylation	K14	4.941	5.277	_EGWVQK(gl)R_
AKT3	Ubiquitylation	K111	1.082		_AIQMVANSLK(gl)QR_
AKT3	Phosphorylation	S120		1.097	_MNCS(ph)PTSQIDNIGEEEMDASTTHHK_
AKT3	Ubiquitylation	K160		0.251	_LLGK(gl)GTFGK_
AKT3	Phosphorylation	T451	-0.091	-0.612	_YFDDEFTAQSITIT(ph)PPDRYDSLGLLELDQR_
AKT3	Phosphorylation	Y456		-0.265	_YFDDEFTAQSITITPPDRY(ph)DSLGLLELDQR_
CAMKK1	Phosphorylation	S74	0.752	0.924	_KLS(ph)LQER_
CAMKK1	Phosphorylation	S82	-0.892	-0.705	_LSLQERPAGS(ph)YLEAQAGPYATGPASHISPR_
CAMKK1	Phosphorylation	S530	0.732	0.456	_EGFGEGGKS(ph)PELPGVQEDEAAS_
CAMKK2	Phosphorylation	S74	0.752	0.924	_KLS(ph)LQER_
CAMKK2	Phosphorylation	S100	0.985	0.940	_KLS(ph)LQER_
CAMKK2	Phosphorylation	S495		0.812	_RS(ph)FGNPFEGSR_
CAMKK2	Phosphorylation	S511		0.155	_SLS(ph)APGNLLTK_
CHUK	Ubiquitylation	K296		-1.637	_GGPVDLTLK(gl)QPR_
IKBKB	Ubiquitylation	K106	0.253		_K(gl)YLNQFENCCGLR_
IKBKB	Phosphorylation	S672	0.670	0.244	_GPVSGS(ph)PDSMNASR_
IRS1	Phosphorylation	S1101	-0.078		_HSS(ph)ETFSSTPSATR_
IRS2	Phosphorylation	S308	-0.079	-0.510	_SKS(ph)QSSGSSATHPISVPGAR_
IRS2	Phosphorylation	T365	0.641	0.852	_T(ph)ASEGDGGAAAGAAAAGAR_
IRS2	Phosphorylation	S367	0.757	0.612	_TAS(ph)EGDGGAAAGAAAAGAR_
IRS2	Phosphorylation	S393	-1.580	-1.221	_PVSVAGSPLS(ph)PGPVR_
IRS2	Phosphorylation	S520	0.359	-1.006	_S(ph)NTPESIAETPPAR_
IRS2	Phosphorylation	T522	-1.103	-0.770	_SNT(ph)PESIAETPPAR_
IRS2	Phosphorylation	T529	0.230	0.164	_S(ph)NTPESIAET(ph)PPAR_
IRS2	Phosphorylation	S562	-0.026	0.439	_RVS(ph)GDAAQDLDR_
IRS2	Phosphorylation	S579	0.542	0.362	_RTYS(ph)LTTPAR_
IRS2	Phosphorylation	S621		-0.190	_LCPSCPAS(ph)SPK_
IRS2	Phosphorylation	S622	-0.195		_LCPSCPASS(ph)PK_
IRS2	Phosphorylation	S681	0.409		_SDDYM(ox)PM(ox)S(ph)PASVSAPK_
IRS2	Phosphorylation	S732	-1.089		_AS(ph)SPAESSPEDSGYM(ox)R_
IRS2	Phosphorylation	S733	-1.027	0.522	_ASS(ph)PAESSPEDSGYM(ox)R_
IRS2	Phosphorylation	S738		0.522	_ASS(ph)PAESS(ph)PEDSGYMR_
IRS2	Phosphorylation	S917	-0.592	-1.025	_S(ph)PGEYINIDFGEPGAR_
IRS2	Phosphorylation	S1164		-0.499	_HSSETFSSTTTVTPVS(ph)PSFAHNPK_
IRS2	Phosphorylation	S1178	0.766	0.277	_HNSAS(ph)VENVSLR_
IRS2	Phosphorylation	T1204		-0.454	_SSEGGVGVGPGGGDEPPT(ph)SPR_
IRS2	Phosphorylation	S1205	-0.291		_SSEGGVGVGPGGGDEPPTS(ph)PR_
IRS4	Phosphorylation	S64	-0.090	-0.062	_S(ph)DSESEEEDLPVGEEVCK_
IRS4	Phosphorylation	S66	-0.354	-0.098	_SDS(ph)ESEEEDLPVGEEVCK_
IRS4	Ubiquitylation	K99	-1.384		_YFVLK(gl)LETADAPAR_
IRS4	Ubiquitylation	K202	-0.581	-0.941	_LILESK(gl)R_
IRS4	Ubiquitylation	K240	-0.370	-0.760	_DVWQVIVK(gl)PR_
IRS4	Ubiquitylation	K248	-0.351	-0.699	_K(gl)ELSGVFR_
IRS4	Phosphorylation	S409	-0.928	-0.559	_FVTPSEPVAHS(ph)R_
IRS4	Phosphorylation	S427	-0.406	0.053	_AVS(ph)VPASFFR_
IRS4	Phosphorylation	S439	-1.003	-1.061	_RLAPS(ph)PARPR_
IRS4	Phosphorylation	S457	0.337		_LS(ph)SEVSGSGSGNFGEEGNPQGK_
IRS4	Phosphorylation	S458	0.236		_LSS(ph)EVSGSGSGNFGEEGNPQGK_
IRS4	Ubiquitylation	K618	0.019	0.005	_SYFGK(gl)LTQSK_
IRS4	Ubiquitylation	K674	-0.511	-0.585	_EVK(gl)DAEIPEGAAR_
IRS4	Phosphorylation	Y743	-0.204	0.833	_GY(ph)MMMFPR_
IRS4	Phosphorylation	S751	-1.810	-1.680	_VS(ph)PPPAPS(ph)PPK_
IRS4	Phosphorylation	S757		-2.068	_VS(ph)PPPAPS(ph)PPK_
IRS4	Phosphorylation	T764		-0.886	_APDT(ph)NKEDDSKDNDSESDYMFMAPGAGAIPK_
IRS4	Phosphorylation	S775		-0.869	_APDTNKEDDSKDNDS(ph)ESDYMFMAPGAGAIPK_
IRS4	Phosphorylation	S777	-0.884	-1.011	_APDTNKEDDSKDNDSES(ph)DYMFMAPGAGAIPK_
IRS4	Phosphorylation	Y779	-0.702	-0.231	_APDTNKEDDSKDNDSESDY(ph)MFMAPGAGAIPK_
IRS4	Phosphorylation	S804	-0.814	-0.440	_S(ph)WSSYFSLPNPFR_
IRS4	Phosphorylation	S810		-1.350	_SWSSYFS(ph)LPNPFR_
IRS4	Phosphorylation	S817	-1.106	-1.146	_S(ph)SPLGQNDNSEYVPM(ox)LPGK_
IRS4	Phosphorylation	S818	-1.196	-1.146	_S(ph)SPLGQNDNSEYVPM(ox)LPGK_
IRS4	Phosphorylation	S826	-0.663	-0.805	_SSPLGQNDNS(ph)EYVPM(ox)LPGK_
IRS4	Ubiquitylation	K835	-1.658	-1.572	_SSPLGQNDNSEYVPM(ox)LPGK(gl)FLGR_
IRS4	Phosphorylation	S872		-2.103	_PGDGGS(ph)PSKPSDHEPPK_
IRS4	Ubiquitylation	K897	-0.308	-0.294	_LSFITK(gl)GYK_
IRS4	Phosphorylation	Y921	0.195	-0.259	_EADSSSDY(ph)VNM(ox)DFTK_
IRS4	Ubiquitylation	K928	-0.946	-1.115	_EADSSSDYVNMDFTK(gl)R_
IRS4	Phosphorylation	S931	-0.413	-1.058	_RES(ph)NTPAPSTQGLPDSWGIIAEPR_
IRS4	Phosphorylation	T933		-1.405	_RESNT(ph)PAPSTQGLPDSWGIIAEPR_
IRS4	Phosphorylation	S1061	0.641	0.325	_IYVVDPFSECCM(ox)DISLS(ph)PSR_
IRS4	Phosphorylation	S1091	-0.218	-0.449	_SQS(ph)FFAAAR_
IRS4	Phosphorylation	S1107	-0.374	-0.244	_AAVSAFPTDS(ph)LER_
IRS4	Phosphorylation	S1231		-1.675	_VPRPPEREDS(ph)DNDDDTHVR_
IRS4	Phosphorylation	S1252		-0.763	_RDNQFDS(ph)PKR_
IRS4	Ubiquitylation	K1254	-2.066	-1.156	_RDNQFDSPK(gl)R_
LEPR	Ubiquitylation	K592		0.126	_MYEVYDAK(gl)SK_
LEPR	Ubiquitylation	K594		0.126	_MYEVYDAK(gl)SK_
MAPK9	Phosphorylation	Y185		3.533	_TACTNFMMTPY(ph)VVTR_
MTOR	Ubiquitylation	K309	-0.762	0.065	_DLMGFGTK(gl)PR_
MTOR	Ubiquitylation	K1257	-1.167	-0.901	_SGQGDALASGPVETGPMKK(gl)_
MTOR	Ubiquitylation	K1395		-1.255	_AYAK(gl)ALHYK_
MTOR	Ubiquitylation	K2066		-1.004	_GPQTLK(gl)ETSFNQAYGR_
MTOR	Ubiquitylation	K2166		-1.304	_IQSIAPSLQVITSK(gl)QRPR_
MTOR	Phosphorylation	T2471		0.329	_KT(ph)GTTVPESIHSFIGDGLVKPEALNK_
NFKB1	Phosphorylation	S907	-0.025	0.113	_TTSQAHSLPLS(ph)PASTR_
NFKBIE	Ubiquitylation	K316		-0.248	_ALVLK(gl)GASR_
PCK1	Phosphorylation	S13	1.866	0.458	_(ac)TTGRTM(ox)YVIPFS(ph)M(ox)GPLGS(ph)PLS(ph)K_
PCK1	Phosphorylation	S19	1.866	-1.827	_(ac)TTGRTM(ox)YVIPFS(ph)M(ox)GPLGS(ph)PLS(ph)K_
PCK1	Phosphorylation	S22	1.866	0.458	_(ac)TTGRTM(ox)YVIPFS(ph)M(ox)GPLGS(ph)PLS(ph)K_
PRKAA1	Ubiquitylation	K271		-0.536	_ATIK(gl)DIR_
PRKAA1	Ubiquitylation	K396		-0.419	_HTLDELNPQK(gl)SK_
PRKAA1	Ubiquitylation	K485	-1.326	-1.554	_SIDDEITEAK(gl)SGTATPQR_
PRKAA2	Ubiquitylation	K271		-0.536	_ATIK(gl)DIR_
PRKAA2	Phosphorylation	S377	-0.020		_MPPLIADS(ph)PK_
PRKAB1	Phosphorylation	S108	-0.357	0.129	_S(ph)HNNFVAILDLPEGEHQYK_
PRKAG1	Ubiquitylation	K78		-0.588	_AAPLWDSK(gl)K_
PRKAG1	Ubiquitylation	K79		-0.588	_AAPLWDSK(gl)K_
PRKAG1	Ubiquitylation	K243	-0.525	-0.505	_VSALPVVDEK(gl)GR_
PRKAG2	Ubiquitylation	K78		-0.588	_AAPLWDSK(gl)K_
PRKAG2	Ubiquitylation	K79		-0.588	_AAPLWDSK(gl)K_
PRKAG2	Ubiquitylation	K243	-0.525	-0.505	_VSALPVVDEK(gl)GR_
PRKCQ	Phosphorylation	S685		0.911	_ALINS(ph)MDQNMFR_
PTPN11	Ubiquitylation	K124	0.562		_EAEK(gl)LLTEK_
SLC2A1	Ubiquitylation	K270	-1.109	0.356	_GTADVTHDLQEM(ox)K(gl)EESR_
SLC2A1	Ubiquitylation	K502	-1.643		_QGGASQSDK(gl)TPEELFHPLGADSQV_
STAT3	Ubiquitylation	K177	0.957		_VVENLQDDFDFNYK(gl)TLK_
STAT3	Ubiquitylation	K180	1.179		_TLK(gl)SQGDMQDLNGNNQSVTR_
STAT3	Ubiquitylation	K244	0.262		_TLTDEELADWK(gl)R_
STAT3	Phosphorylation	T714		-0.338	_FICVT(ph)PTTCSNTIDLPMS(ph)PR_
STAT3	Phosphorylation	S727	-0.079	0.156	_FICVTPTTCSNTIDLPMS(ph)PR_
STK11	Phosphorylation	S31	0.437	0.073	_IDS(ph)TEVIYQPR_
STK11	Phosphorylation	T32	1.256	0.248	_IDS(ph)TEVIYQPR_
TNFRSF1A	Ubiquitylation	K242		-0.111	_SK(gl)LYSIVCGK_
TRAF2	Phosphorylation	T7	-0.822	-1.190	_(ac)AAASVT(ph)PPGSLELLQPGFSK_
TRAF2	Ubiquitylation	K27	-0.253	2.194	_TLLGTK(gl)LEAK_
TRAF2	Ubiquitylation	K119		0.519	_GTLK(gl)EYESCHEGR_
TRAF2	Ubiquitylation	K176	-1.233	1.022	_APCCGADVK(gl)AHHEVCPK_
TRAF2	Ubiquitylation	K207	0.147	0.918	_FQDHVK(gl)TCGK_
TRAF2	Ubiquitylation	K481	-0.507	0.417	_MEAK(gl)NSYVR_