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Query: CAMKK2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CAMKK2 0 1.925 1.040 -0.430

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CAMKK2 Phosphorylation S100 0.985 0.940 _KLS(ph)LQER_
CAMKK2 Phosphorylation S74 0.752 0.924 _KLS(ph)LQER_
CAMKK2 Phosphorylation S495 0.812 _RS(ph)FGNPFEGSR_
CAMKK2 Phosphorylation S511 0.155 _SLS(ph)APGNLLTK_

Background Information for CAMKK2:


Pubmed-CAMKK2 »
Uniprot-CAMKK2 »
Biogrid-CAMKK2 »
ProteomicsDB-CAMKK2 »

Tumorportal-CAMKK2 »
COSMIC-CAMKK2 »
GenomeRNAi-CAMKK2 »
Genecards-CAMKK2


Protein-protein Interactions for CAMKK2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ALOX5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C6orf141 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM196A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GCHFR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAPK14 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CAMKK2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Kinase-like_dom IPR011009 0.03
Category members Prot_kinase_dom IPR000719 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring CAMKK2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CAMKK2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0005516 calmodulin binding Database 0.74
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0046777 protein autophosphorylation Database 0.23
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members Pathway Pathway_437 PID_VEGFR1_2_PATHWAY 0 0.13
Category members GO Category GO:0005509 calcium ion binding Database 0.11
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0045859 regulation of protein kinase activity Database 0.01
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members Pathway Pathway_1167 BIOCARTA_CACAM_PATHWAY 0 0
Category members Pathway Pathway_40 KEGG_ADIPOCYTOKINE_SIGNALING_PATHWAY 0 0
Category members GO Category GO:0000165 MAPK cascade Database 0
Category members GO Category GO:0004683 calmodulin-dependent protein kinase activity Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0018108 peptidyl-tyrosine phosphorylation Database 0
Category members GO Category GO:0019722 calcium-mediated signaling Database 0
Category members GO Category GO:0042995 cell projection Database 0


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