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Query: PCK2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PCK2 2 1.558 0.680 -0.790 -0.618 1.207 -2.619 1.882 1.706

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for PCK2:


Pubmed-PCK2 »
Uniprot-PCK2 »
Biogrid-PCK2 »
ProteomicsDB-PCK2 »

Tumorportal-PCK2 »
COSMIC-PCK2 »
GenomeRNAi-PCK2 »
Genecards-PCK2


Protein-protein Interactions for PCK2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PCK2 Cat. description Hein, Mann, Cell 2015
Category members IP bait NDUFS6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCK2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PCK2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PEP_carboxykinase_GTP IPR008209 0.09
Category members PEP_carboxykinase_N IPR008210 0.09


Protein complexes (CORUM database) featuring PCK2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PCK2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members Pathway Pathway_3 KEGG_CITRATE_CYCLE_TCA_CYCLE 0 3.83
Category members Pathway Pathway_35 REACTOME_GLUCOSE_METABOLISM 0 1.79
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0006094 gluconeogenesis Database 1.42
Category members Pathway Pathway_33 REACTOME_GLUCONEOGENESIS 0 1.41
Category members Pathway Pathway_16 KEGG_PYRUVATE_METABOLISM 0 1.34
Category members GO Category GO:0005759 mitochondrial matrix Database 0.59
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_34 REACTOME_METABOLISM_OF_CARBOHYDRATES 0 0.31
Category members Pathway Pathway_45 PID_REG_GR_PATHWAY 0 0.31
Category members GO Category GO:0006006 glucose metabolic process Database 0.28
Category members GO Category GO:0016301 kinase activity Database 0.23
Category members GO Category GO:0017076 purine nucleotide binding Database 0.23
Category members Pathway Pathway_44 KEGG_INSULIN_SIGNALING_PATHWAY 0 0.21
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members GO Category GO:0004611 phosphoenolpyruvate carboxykinase activity Database 0.09
Category members GO Category GO:0004613 phosphoenolpyruvate carboxykinase (GTP) activity Database 0.09
Category members GO Category GO:0032024 positive regulation of insulin secretion Database 0.07
Category members GO Category GO:0005975 carbohydrate metabolic process Database 0.07
Category members GO Category GO:0051384 response to glucocorticoid Database 0.04
Category members GO Category GO:0006090 pyruvate metabolic process Database 0.04
Category members Pathway Pathway_36 KEGG_PROXIMAL_TUBULE_BICARBONATE_RECLAMATION 0 0
Category members Pathway Pathway_40 KEGG_ADIPOCYTOKINE_SIGNALING_PATHWAY 0 0
Category members Pathway Pathway_43 KEGG_PPAR_SIGNALING_PATHWAY 0 0
Category members GO Category GO:0006107 oxaloacetate metabolic process Database 0
Category members GO Category GO:0006116 NADH oxidation Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0071333 cellular response to glucose stimulus Database 0


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