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positive regulation of insulin secretion
(GO:0032024)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
PCK2 2 0.680 -0.790 -0.618 1.207 -2.619 1.882 1.706
OXCT1 1 0.450 -0.370 2.793 0.677 0.862
BAD 0 -0.660 1.190
PSMD9 0 -0.440 1.070
PFKFB2 0 -0.070 0.400
SOX4 0 1.610 -0.930
GLUL 0 0.010 -0.210 -2.755
GLUD1 0 -0.650 1.550 -0.425 0.134 -1.823 -0.110 0.055
GLUD1 0 1.090 -0.240 -0.425 0.134 -1.823 -0.110 0.055
TCF7L2 0 -0.550 0.790 -0.741
PFKM 0 -0.290 -0.020 -0.313
PFKM 0 -0.290 -0.020
MCU 0 0.220 -0.400 0.109 0.653
IRS2 0 -0.190 -0.130
MGEA5 0 0.450 -0.320 -0.773

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
BAD Phosphorylation S74 -0.904 -0.452 _HS(ph)SYPAGTEDDEGM(ox)GEEPSPFR_
BAD Phosphorylation S75 -0.914 -0.660 _HSS(ph)YPAGTEDDEGMGEEPSPFR_
BAD Phosphorylation S97 0.056 _S(ph)RSAPPNLWAAQR_
BAD Phosphorylation S99 -0.299 0.161 _S(ph)APPNLWAAQR_
BAD Phosphorylation S118 1.277 1.089 _RM(ox)S(ph)DEFVDSFKK_
GLUD1 Ubiquitylation K191 -1.517 _INPK(gl)NYTDNELEK_
GLUD1 Ubiquitylation K212 0.459 _FTMELAKK(gl)_
GLUD1 Ubiquitylation K390 -1.159 _QLTK(gl)SNAPR_
GLUL Ubiquitylation K11 -0.594 0.440 _(ac)TTSASSHLNK(gl)GIK_
GLUL Ubiquitylation K14 -0.422 -0.252 _GIK(gl)QVYMSLPQGEK_
GLUL Ubiquitylation K91 -0.709 _DPFRK(gl)DPNK_
GLUL Ubiquitylation K95 0.072 -0.295 _DPNK(gl)LVLCEVFK_
GLUL Ubiquitylation K276 -0.768 _YIEEAIEK(gl)LSK_
GLUL Ubiquitylation K279 0.464 _YIEEAIEKLSK(gl)_
GLUL Ubiquitylation K291 -0.474 _AYDPK(gl)GGLDNARR_
GLUL Ubiquitylation K372 -1.094 -0.523 _TCLLNETGDEPFQYK(gl)N_
IRS2 Phosphorylation S308 -0.079 -0.510 _SKS(ph)QSSGSSATHPISVPGAR_
IRS2 Phosphorylation T365 0.641 0.852 _T(ph)ASEGDGGAAAGAAAAGAR_
IRS2 Phosphorylation S367 0.757 0.612 _TAS(ph)EGDGGAAAGAAAAGAR_
IRS2 Phosphorylation S393 -1.580 -1.221 _PVSVAGSPLS(ph)PGPVR_
IRS2 Phosphorylation S520 0.359 -1.006 _S(ph)NTPESIAETPPAR_
IRS2 Phosphorylation T522 -1.103 -0.770 _SNT(ph)PESIAETPPAR_
IRS2 Phosphorylation T529 0.230 0.164 _S(ph)NTPESIAET(ph)PPAR_
IRS2 Phosphorylation S562 -0.026 0.439 _RVS(ph)GDAAQDLDR_
IRS2 Phosphorylation S579 0.542 0.362 _RTYS(ph)LTTPAR_
IRS2 Phosphorylation S621 -0.190 _LCPSCPAS(ph)SPK_
IRS2 Phosphorylation S622 -0.195 _LCPSCPASS(ph)PK_
IRS2 Phosphorylation S681 0.409 _SDDYM(ox)PM(ox)S(ph)PASVSAPK_
IRS2 Phosphorylation S732 -1.089 _AS(ph)SPAESSPEDSGYM(ox)R_
IRS2 Phosphorylation S733 -1.027 0.522 _ASS(ph)PAESSPEDSGYM(ox)R_
IRS2 Phosphorylation S738 0.522 _ASS(ph)PAESS(ph)PEDSGYMR_
IRS2 Phosphorylation S917 -0.592 -1.025 _S(ph)PGEYINIDFGEPGAR_
IRS2 Phosphorylation S1164 -0.499 _HSSETFSSTTTVTPVS(ph)PSFAHNPK_
IRS2 Phosphorylation S1178 0.766 0.277 _HNSAS(ph)VENVSLR_
IRS2 Phosphorylation T1204 -0.454 _SSEGGVGVGPGGGDEPPT(ph)SPR_
IRS2 Phosphorylation S1205 -0.291 _SSEGGVGVGPGGGDEPPTS(ph)PR_
MGEA5 Ubiquitylation K155 0.083 _EVSTLK(gl)R_
MGEA5 Ubiquitylation K157 -0.558 _K(gl)LDQVSQFGCR_
MGEA5 Ubiquitylation K297 -0.826 _LFLGPYK(gl)GR_
MGEA5 Phosphorylation S364 0.161 0.083 _LENEGS(ph)DEDIETDVLYSPQMALK_
MGEA5 Ubiquitylation K597 -0.899 _ANSSVVSVNCK(gl)GK_
MGEA5 Ubiquitylation K599 -0.899 _ANSSVVSVNCK(gl)GK_
MGEA5 Ubiquitylation K730 0.165 -0.163 _DEASVYK(gl)ICR_
MGEA5 Ubiquitylation K885 -0.922 -1.207 _GAFCEVRPDDK(gl)R_
PFKFB2 Ubiquitylation K305 1.201 _VWTSQLK(gl)R_
PFKFB2 Phosphorylation S466 0.350 0.410 _RNS(ph)FTPLSSSNTIR_
PFKFB2 Phosphorylation T468 0.351 0.361 _RNSFT(ph)PLSSSNTIR_
PFKFB2 Phosphorylation S493 -0.264 -0.110 _NYSVGSRPLKPLS(ph)PLR_
PFKM Ubiquitylation K178 -0.734 _AAYNLVK(gl)R_
PFKM Ubiquitylation K215 -0.787 -0.246 _AGK(gl)ITDEEATK_
PFKM Ubiquitylation K427 -0.699 _LPLMECVQVTK(gl)DVTK_
PFKM Ubiquitylation K431 -0.696 _DVTK(gl)AMDEK_
PSMD9 Ubiquitylation K117 0.095 _DMAEAHK(gl)EAMSR_
PSMD9 Ubiquitylation K123 -1.236 -0.524 _K(gl)LGQSESQGPPR_
SOX4 Phosphorylation S354 -0.003 _SSAASSPAAGRS(ph)PADHR_
TCF7L2 Ubiquitylation K88 -0.867 -0.222 _ESLEEAAK(gl)R_


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