bioLOGIC-db

bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

Query: MGEA5

RNAi screen result	RNAPII IP (PI)	CSB IP	CSB IP (PI)	Chrom.	Chrom. (PI)	Phosphorylation	Ubiquitylation
W

[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:
Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen

Gene name	Point score	Z-score sums	RNAi high	RNAi low	RNAPII-IP (PI)	CSB-IP	CSB-IP (PI)	Chrom.	Chrom. (PI)
MGEA5	0	-0.280	0.450	-0.320	-0.773

PTM Sites:
Back to Protein Results | Red/green: hit at lower/upper end of the respective screen

Gene name	PTM type	PTM site	UV	UV (PI)	Sequence
MGEA5	Ubiquitylation	K155		0.083	_EVSTLK(gl)R_
MGEA5	Phosphorylation	S364	0.161	0.083	_LENEGS(ph)DEDIETDVLYSPQMALK_
MGEA5	Ubiquitylation	K730	0.165	-0.163	_DEASVYK(gl)ICR_
MGEA5	Ubiquitylation	K157		-0.558	_K(gl)LDQVSQFGCR_
MGEA5	Ubiquitylation	K297		-0.826	_LFLGPYK(gl)GR_
MGEA5	Ubiquitylation	K597		-0.899	_ANSSVVSVNCK(gl)GK_
MGEA5	Ubiquitylation	K599		-0.899	_ANSSVVSVNCK(gl)GK_
MGEA5	Ubiquitylation	K885	-0.922	-1.207	_GAFCEVRPDDK(gl)R_

Background Information for MGEA5:

Pubmed-MGEA5 »

Uniprot-MGEA5 »

Biogrid-MGEA5 »

ProteomicsDB-MGEA5 »

Tumorportal-MGEA5 »

COSMIC-MGEA5 »

GenomeRNAi-MGEA5 »

Genecards-MGEA5

Protein-protein Interactions for MGEA5

Show screen data for	Category Name and Description	Link to cat description	Data Source
Category members	IP bait C1QTNF9	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait C7orf60	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait FAM158A	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait FMO5	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait HRSP12	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait KIAA1949	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait LACTB2	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait OBFC1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015

Protein Domains in MGEA5

	Domain name	Domain Description	TC-NER relevance -log10(p-value)
Category members	Acyl_CoA_acyltransferase	IPR016181	0
Category members	Glycoside_hydrolase_SF	IPR017853	0

Protein complexes (CORUM database) featuring MGEA5

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)

Categories featuring MGEA5

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	GO Category	GO:0005634	nucleus	Database	INF
Category members	GO Category	GO:0005737	cytoplasm	Database	12.81
Category members	GO Category	GO:0016573	histone acetylation	Database	1.24
Category members	GO Category	GO:0004402	histone acetyltransferase activity	Database	0.56
Category members	GO Category	GO:0006612	protein targeting to membrane	Database	0.29
Category members	GO Category	GO:0048545	response to steroid hormone	Database	0.11
Category members	GO Category	GO:0004415	hyalurononglucosaminidase activity	Database	0.11
Category members	GO Category	GO:0032024	positive regulation of insulin secretion	Database	0.07
Category members	GO Category	GO:0060124	positive regulation of growth hormone secretion	Database	0.01
Category members	GO Category	GO:0006044	N-acetylglucosamine metabolic process	Database	0
Category members	GO Category	GO:0006516	glycoprotein catabolic process	Database	0
Category members	GO Category	GO:0007568	aging	Database	0
Category members	GO Category	GO:0010524	positive regulation of calcium ion transport into cytosol	Database	0
Category members	GO Category	GO:0043243	positive regulation of protein complex disassembly	Database	0
Category members	GO Category	GO:0045862	positive regulation of proteolysis	Database	0
Category members	GO Category	GO:0046060	dATP metabolic process	Database	0
Category members	GO Category	GO:0046326	positive regulation of glucose import	Database	0
Category members	GO Category	GO:0051054	positive regulation of DNA metabolic process	Database	0
Category members	GO Category	GO:0051901	positive regulation of mitochondrial depolarization	Database	0
Category members	GO Category	GO:0051928	positive regulation of calcium ion transport	Database	0
Category members	GO Category	GO:0070265	necrotic cell death	Database	0