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Query: SOX4

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SOX4 0 -0.003 1.610 -0.930

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SOX4 Phosphorylation S354 -0.003 _SSAASSPAAGRS(ph)PADHR_

Background Information for SOX4:


Pubmed-SOX4 »
Uniprot-SOX4 »
Biogrid-SOX4 »
ProteomicsDB-SOX4 »

Tumorportal-SOX4 »
COSMIC-SOX4 »
GenomeRNAi-SOX4 »
Genecards-SOX4


Protein-protein Interactions for SOX4
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in SOX4
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members HMG_box_dom IPR009071 0.31
Category members SOX-12/11/4a IPR017386 0


Protein complexes (CORUM database) featuring SOX4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SOX4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest Database 1.39
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0008285 negative regulation of cell proliferation Database 0.28
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0043065 positive regulation of apoptotic process Database 0.26
Category members GO Category GO:0046826 negative regulation of protein export from nucleus Database 0.23
Category members GO Category GO:0031647 regulation of protein stability Database 0.21
Category members GO Category GO:0042593 glucose homeostasis Database 0.18
Category members GO Category GO:0000976 transcription regulatory region sequence-specific DNA binding Database 0.13
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0032024 positive regulation of insulin secretion Database 0.07
Category members GO Category GO:0050821 protein stabilization Database 0.04
Category members GO Category GO:0001046 core promoter sequence-specific DNA binding Database 0
Category members GO Category GO:0001071 nucleic acid binding transcription factor activity Database 0
Category members GO Category GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription Database 0
Category members GO Category GO:0001105 RNA polymerase II transcription coactivator activity Database 0
Category members GO Category GO:0001501 skeletal system development Database 0
Category members GO Category GO:0001841 neural tube formation Database 0
Category members GO Category GO:0002328 pro-B cell differentiation Database 0
Category members GO Category GO:0003183 mitral valve morphogenesis Database 0
Category members GO Category GO:0003211 cardiac ventricle formation Database 0
Category members GO Category GO:0003215 cardiac right ventricle morphogenesis Database 0
Category members GO Category GO:0003289 atrial septum primum morphogenesis Database 0
Category members GO Category GO:0003357 noradrenergic neuron differentiation Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0007507 heart development Database 0
Category members GO Category GO:0008284 positive regulation of cell proliferation Database 0
Category members GO Category GO:0014009 glial cell proliferation Database 0
Category members GO Category GO:0021510 spinal cord development Database 0
Category members GO Category GO:0021522 spinal cord motor neuron differentiation Database 0
Category members GO Category GO:0021782 glial cell development Database 0
Category members GO Category GO:0030177 positive regulation of Wnt signaling pathway Database 0
Category members GO Category GO:0030217 T cell differentiation Database 0
Category members GO Category GO:0031018 endocrine pancreas development Database 0
Category members GO Category GO:0031397 negative regulation of protein ubiquitination Database 0
Category members GO Category GO:0035019 somatic stem cell maintenance Database 0
Category members GO Category GO:0035910 ascending aorta morphogenesis Database 0
Category members GO Category GO:0042769 DNA damage response, detection of DNA damage Database 0
Category members GO Category GO:0045727 positive regulation of translation Database 0
Category members GO Category GO:0048485 sympathetic nervous system development Database 0
Category members GO Category GO:0060070 canonical Wnt signaling pathway Database 0
Category members GO Category GO:0060174 limb bud formation Database 0
Category members GO Category GO:0060412 ventricular septum morphogenesis Database 0
Category members GO Category GO:0060548 negative regulation of cell death Database 0
Category members GO Category GO:0060563 neuroepithelial cell differentiation Database 0
Category members GO Category GO:0060993 kidney morphogenesis Database 0
Category members GO Category GO:0071333 cellular response to glucose stimulus Database 0


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