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RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
(GO:0001077)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
JUN 3 -0.930 0.930 -0.126
ATF2 2 -1.380 1.800
POU2F1 2 -0.480 0.830
PBX2 2 -0.170 0.670 -0.186 -0.124
TFAP4 1 1.270 -0.790
MEF2A 0 0.820 -0.530
MEF2A 0 0.820 -0.530
MEF2C 0 -0.980 1.550
MEF2C 0 -0.980 1.550
HIF1A 0 -0.480 0.400
DLX5 0 -0.590 0.650 -1.286 0.204
GATA3 0 0.000 -0.660
SRF 0 0.670 -1.020
HOXC13 0 0.030 0.890 -0.027 0.427
HOXC13 0 0.030 0.890 -1.413 0.651
SOX4 0 1.610 -0.930
RUNX2 0
BCL11B 0 -0.600 -0.050 -0.645 -0.251
FOXA1 0 1.190 -0.010
TP53 0 -1.070 1.050 -2.808 0.076 -0.094 0.436 0.497
NFIB 0 -1.030 1.080 -0.711 0.025 0.306 1.031
HMGA2 0 0.340 -0.490
HAND2 0 0.000 0.600
HNRNPK 0 -0.160 0.450 -0.273 -1.081 -0.609 -0.231 -0.195
HNRNPK 0 -0.160 0.450
RBPJ 0 1.900 -0.160 -0.367 0.284 0.723 -0.090 0.134
CEBPB 0 0.400 -0.930
FOXG1 0 -0.510 1.000 -1.217 -0.424 0.659
FOXG1 0 0.550 -0.250 -1.217 -0.424 0.659
SOX2 0 -0.250 0.870
SP1 0 0.404 0.333 0.650
PBX1 0 -0.600 0.280
PBX1 0 -0.600 0.280 -0.186 -0.124
PLSCR1 0 -0.520 0.570
ZNF292 0 0.540 0.450 0.305 0.001

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ATF2 Phosphorylation T71 -1.263 -1.166 _NDSVIVADQTPT(ph)PTR_
ATF2 Phosphorylation S90 2.624 2.389 _NCEEVGLFNELAS(ph)PFENEFKK_
ATF2 Phosphorylation S112 1.025 1.118 _MPLDLS(ph)PLATPIIR_
BCL11B Phosphorylation S97 0.399 -0.308 _ALDKDS(ph)PPPSSR_
BCL11B Phosphorylation S129 -0.095 _VSEPVEIGIQVTPDEDDHLLS(ph)PTK_
BCL11B Phosphorylation T131 -0.689 _VSEPVEIGIQVTPDEDDHLLSPT(ph)K_
BCL11B Phosphorylation T376 -0.644 -1.439 _ELAGNSST(ph)PPPVS(ph)PGR_
BCL11B Phosphorylation S381 -0.644 -1.439 _ELAGNSST(ph)PPPVS(ph)PGR_
BCL11B Phosphorylation T754 0.033 -0.354 _FST(ph)PPGDLLDGGLSGR_
CEBPB Phosphorylation S231 -0.660 _AYLGYQAVPSGSSGSLSTSSSSS(ph)PPGTPSPADAK_
DLX5 Phosphorylation S225 -0.821 _SGEIPSEQHPGAS(ph)AS(ph)PPCASPPVSAPASWDFGVPQR_
DLX5 Phosphorylation S227 -1.137 _SGEIPSEQHPGASAS(ph)PPCAS(ph)PPVSAPASWDFGVPQR_
DLX5 Phosphorylation S232 -1.137 _SGEIPSEQHPGASAS(ph)PPCAS(ph)PPVSAPASWDFGVPQR_
FOXA1 Phosphorylation S331 -0.760 -0.866 _TGQLEGAPAPGPAAS(ph)PQTLDHSGATATGGASELK_
FOXG1 Phosphorylation S6 0.325 0.055 _YS(ph)VSSPNSLGVVPYLGGEQSYYR_
FOXG1 Phosphorylation S235 -1.239 _TENGTCPS(ph)PPQPLS(ph)PAAALGSGSAAAVPK_
FOXG1 Phosphorylation S241 -1.239 _TENGTCPS(ph)PPQPLS(ph)PAAALGSGSAAAVPK_
FOXG1 Phosphorylation S259 -0.376 -0.198 _IES(ph)PDSSSSSLSSGSSPPGSLPSAR_
FOXG1 Phosphorylation S320 0.313 0.178 _GS(ph)PQSAAAELSSGLLASAAASSR_
FOXG1 Phosphorylation S323 0.347 _GSPQS(ph)AAAELSSGLLASAAASSR_
FOXG1 Ubiquitylation K554 -0.030 0.013 _TSGAFVYDCSK(gl)F_
GATA3 Phosphorylation S162 -1.195 -0.563 _DVS(ph)PDPSLSTPGSAGSAR_
HAND2 Ubiquitylation K183 0.800 1.236 _K(gl)ELNEILK_
HIF1A Ubiquitylation K10 -1.686 _(ac)MEGAGGANDK(gl)K_
HIF1A Ubiquitylation K11 -1.686 _(ac)MEGAGGANDK(gl)K_
HIF1A Ubiquitylation K173 -0.662 _MK(gl)CTLTSR_
HIF1A Ubiquitylation K186 -0.590 _TMNIK(gl)SATWK_
HIF1A Ubiquitylation K252 -0.784 _HSLDM(ox)K(gl)FSYCDER_
HIF1A Ubiquitylation K371 -0.508 _PVESSDMK(gl)MTQLFTK_
HIF1A Ubiquitylation K378 -0.077 _MTQLFTK(gl)VESEDTSSLFDK_
HIF1A Ubiquitylation K390 -0.348 _VESEDTSSLFDK(gl)LKK_
HIF1A Ubiquitylation K392 -0.546 _VESEDTSSLFDKLK(gl)_
HIF1A Ubiquitylation K393 -0.451 _VESEDTSSLFDKLKK(gl)_
HIF1A Ubiquitylation K710 -1.696 _TTVPEEELNPK(gl)ILALQNAQR_
HMGA2 Phosphorylation S44 -0.564 -0.762 _KQQQEPTGEPS(ph)PK_
HMGA2 Phosphorylation S105 -0.055 -0.046 _KPAQEETEETSSQES(ph)AEED_
HNRNPK Ubiquitylation K34 -0.398 0.033 _RPAEDMEEEQAFK(gl)R_
HNRNPK Ubiquitylation K52 1.081 1.257 _ILLQSK(gl)NAGAVIGK_
HNRNPK Ubiquitylation K60 0.068 _NAGAVIGK(gl)GGK(gl)NIK_
HNRNPK Ubiquitylation K63 -0.065 0.839 _NAGAVIGK(gl)GGK(gl)NIK_
HNRNPK Phosphorylation S116 0.499 0.377 _IIPTLEEGLQLPS(ph)PTATSQLPLESDAVECLNYQHYK_
HNRNPK Phosphorylation T118 0.679 _KIIPTLEEGLQLPSPT(ph)ATSQLPLESDAVECLNYQHYK_
HNRNPK Phosphorylation T120 0.365 _IIPTLEEGLQLPSPTAT(ph)SQLPLESDAVECLNYQHYK_
HNRNPK Ubiquitylation K163 0.329 _LLIHQSLAGGIIGVK(gl)GAK_
HNRNPK Ubiquitylation K179 -0.020 -0.161 _ENTQTTIK(gl)LFQECCPHSTDR_
HNRNPK Ubiquitylation K198 -0.013 0.077 _VVLIGGK(gl)PDR_
HNRNPK Phosphorylation S216 0.474 0.302 _IILDLISES(ph)PIK_
HNRNPK Ubiquitylation K219 -0.125 0.098 _IILDLISESPIK(gl)GR_
HNRNPK Phosphorylation S284 0.141 -0.133 _RDYDDMS(ph)PR_
HNRNPK Phosphorylation S379 -0.481 0.342 _GS(ph)YGDLGGPIITTQVTIPK_
HNRNPK Ubiquitylation K405 0.830 0.378 _DLAGSIIGK(gl)GGQR_
HOXC13 Ubiquitylation K335 0.431 0.162 _VQLK(gl)ELER_
JUN Phosphorylation S58 -0.167 -1.247 _AKNS(ph)DLLTSPDVGLLK_
JUN Phosphorylation T62 2.545 1.674 _NSDLLT(ph)SPDVGLLK_
JUN Phosphorylation S63 2.030 1.458 _NSDLLTS(ph)PDVGLLK_
JUN Ubiquitylation K70 9.213 _NSDLLTSPDVGLLK(gl)_
JUN Phosphorylation S73 1.499 0.845 _LAS(ph)PELER_
JUN Phosphorylation S243 -0.642 -1.399 _LQALKEEPQTVPEMPGETPPLS(ph)PIDMESQER_
JUN Ubiquitylation K309 1.034 0.155 _EQVAQLK(gl)QK_
MEF2A Ubiquitylation K23 -0.140 _QVTFTK(gl)R_
MEF2A Phosphorylation S235 0.664 -0.092 _AS(ph)PNLIGATGANSLGK_
MEF2A Phosphorylation T253 -1.271 _VMPT(ph)KSPPPPGGGNLGMNSR_
MEF2A Phosphorylation S255 -1.235 _VMPTKS(ph)PPPPGGGNLGMNSR_
MEF2A Phosphorylation S408 -0.173 -0.049 _SEPIS(ph)PPRDR_
MEF2A Phosphorylation S494 -0.858 -1.232 _GDFHSPIVLGRPPNTEDRES(ph)PSVK_
MEF2C Ubiquitylation K23 -0.140 _QVTFTK(gl)R_
MEF2C Phosphorylation S240 0.008 0.302 _NS(ph)PGLLVSPGNLNK_
MEF2C Phosphorylation S406 0.272 0.338 _SEPVS(ph)PPRDR_
NFIB Phosphorylation S294 -1.873 _TISIDENM(ox)EPSPTGDFYPSPS(ph)SPAAGSR_
NFIB Phosphorylation S295 -1.280 _TISIDENMEPSPTGDFYPSPSS(ph)PAAGSR_
NFIB Phosphorylation S300 -1.728 _TISIDENM(ox)EPSPTGDFYPSPSSPAAGS(ph)R_
NFIB Phosphorylation S311 1.021 0.671 _DQDMS(ph)SPTTM(ox)K_
NFIB Phosphorylation S312 0.764 0.746 _DQDMSS(ph)PTTMK_
NFIB Phosphorylation T314 0.827 _DQDMSSPT(ph)TMK_
NFIB Phosphorylation S325 0.852 _KPEKPLFS(ph)SASPQDSSPR_
NFIB Phosphorylation S328 1.295 0.637 _KPEKPLFSSAS(ph)PQDSSPR_
NFIB Phosphorylation S332 -0.428 -1.102 _KPEKPLFSSASPQDS(ph)SPR_
NFIB Phosphorylation S333 -0.428 _KPEKPLFSSASPQDS(ph)SPR_
PBX1 Ubiquitylation K164 -0.541 _SK(gl)LAQIR_
PBX1 Ubiquitylation K195 -1.614 _TRPISPK(gl)EIER_
PBX2 Ubiquitylation K164 -0.541 _SK(gl)LAQIR_
PLSCR1 Ubiquitylation K223 -0.674 -0.495 _FTIQNEK(gl)REDVLK_
POU2F1 Phosphorylation S8 1.971 2.219 _(ac)ADGGAAS(ph)QDESSAAAAAAADSR_
POU2F1 Phosphorylation S408 0.932 1.562 _RTS(ph)IETNIR_
POU2F1 Phosphorylation S471 -0.483 -0.496 _RINPPSSGGTSSS(ph)PIK_
RUNX2 Phosphorylation S96 0.504 -0.399 _RFS(ph)PPSSSLQPGK_
RUNX2 Ubiquitylation K244 0.258 _NASAVMK(gl)NQVAR_
SOX2 Phosphorylation S251 0.157 -0.109 _SEASSS(ph)PPVVTSSSHSR_
SOX4 Phosphorylation S354 -0.003 _SSAASSPAAGRS(ph)PADHR_
SP1 Phosphorylation S2 0.834 1.114 _(ac)S(ph)DQDHSMDEMTAVVK_
SP1 Phosphorylation S7 0.586 0.217 _(ac)SDQDHS(ph)MDEMTAVVK_
SP1 Phosphorylation S56 -0.154 _SSSTGSSSSTGGGGQES(ph)QPSPLALLAATCSR_
SP1 Phosphorylation S59 -0.217 -0.135 _SSSTGSSSSTGGGGQESQPS(ph)PLALLAATCSR_
SRF Phosphorylation S224 -0.512 -0.458 _ALIQTCLNSPDS(ph)PPR_
TFAP4 Ubiquitylation K114 1.008 2.315 _LLQQNTQLK(gl)R_
TFAP4 Phosphorylation S123 0.832 _RFIQELSGS(ph)SPKR_
TFAP4 Phosphorylation S124 0.584 0.494 _RFIQELSGSS(ph)PK_
TP53 Ubiquitylation K120 -0.188 _LGFLHSGTAK(gl)SVTCTYSPALNK_
TP53 Ubiquitylation K164 0.157 -1.260 _AMAIYK(gl)QSQHMTEVVR_
TP53 Phosphorylation S314 -0.695 -1.000 _ALPNNTSS(ph)SPQPK_
TP53 Phosphorylation S315 -0.762 -0.959 _RALPNNTSSS(ph)PQPK_
TP53 Ubiquitylation K320 -0.978 _ALPNNTSSSPQPKK(gl)_
TP53 Ubiquitylation K357 -0.231 -0.823 _ELNEALELKDAQAGK(gl)EPGGSR_


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