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Query: FOXG1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
FOXG1 0 0.673 -0.510 1.000 -1.217 -0.424 0.659
FOXG1 0 0.673 0.550 -0.250 -1.217 -0.424 0.659

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
FOXG1 Phosphorylation S323 0.347 _GSPQS(ph)AAAELSSGLLASAAASSR_
FOXG1 Phosphorylation S320 0.313 0.178 _GS(ph)PQSAAAELSSGLLASAAASSR_
FOXG1 Phosphorylation S6 0.325 0.055 _YS(ph)VSSPNSLGVVPYLGGEQSYYR_
FOXG1 Ubiquitylation K554 -0.030 0.013 _TSGAFVYDCSK(gl)F_
FOXG1 Phosphorylation S259 -0.376 -0.198 _IES(ph)PDSSSSSLSSGSSPPGSLPSAR_
FOXG1 Phosphorylation S235 -1.239 _TENGTCPS(ph)PPQPLS(ph)PAAALGSGSAAAVPK_
FOXG1 Phosphorylation S241 -1.239 _TENGTCPS(ph)PPQPLS(ph)PAAALGSGSAAAVPK_

Background Information for FOXG1:


Pubmed-FOXG1 »
Uniprot-FOXG1 »
Biogrid-FOXG1 »
ProteomicsDB-FOXG1 »

Tumorportal-FOXG1 »
COSMIC-FOXG1 »
GenomeRNAi-FOXG1 »
Genecards-FOXG1


Protein-protein Interactions for FOXG1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PROZ Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait THSD4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in FOXG1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members TF_fork_head IPR001766 0


Protein complexes (CORUM database) featuring FOXG1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2707 SMAD3-SMAD4-FOXO3-FOXG1 complex Database 0.32


Categories featuring FOXG1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members Pathway Pathway_845 PID_SMAD2_3NUCLEAR_PATHWAY 0 0.46
Category members GO Category GO:0021987 cerebral cortex development Database 0.37
Category members GO Category GO:0043565 sequence-specific DNA binding Database 0.18
Category members GO Category GO:0022008 neurogenesis Database 0.16
Category members GO Category GO:0051726 regulation of cell cycle Database 0.11
Category members GO Category GO:0048667 cell morphogenesis involved in neuron differentiation Database 0.07
Category members GO Category GO:0045787 positive regulation of cell cycle Database 0.04
Category members GO Category GO:0045665 negative regulation of neuron differentiation Database 0.04
Category members GO Category GO:0021954 central nervous system neuron development Database 0.02
Category members Disease phenotype Atypical_Rett_syndrome Atypical Rett syndrome Database 0
Category members GO Category GO:0002052 positive regulation of neuroblast proliferation Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0007346 regulation of mitotic cell cycle Database 0
Category members GO Category GO:0007420 brain development Database 0
Category members GO Category GO:0007568 aging Database 0
Category members GO Category GO:0009953 dorsal/ventral pattern formation Database 0
Category members GO Category GO:0010468 regulation of gene expression Database 0
Category members GO Category GO:0016199 axon midline choice point recognition Database 0
Category members GO Category GO:0030900 forebrain development Database 0
Category members GO Category GO:0042472 inner ear morphogenesis Database 0
Category members GO Category GO:0048664 neuron fate determination Database 0


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