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Results for the Category
negative regulation of neuron differentiation
(GO:0045665)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
PBX2 2 -0.170 0.670 -0.186 -0.124
MED1 1 0.780 -0.520 -1.530 -0.219
CTDSP1 1 2.470 -1.010
ASPM 0 0.390 0.300 0.580 0.002 -0.388
RHOA 0 -0.510 1.370 -0.485 0.532 0.279
REST 0 -0.120 -0.050 -0.002 -1.235 -0.636
BMP7 0
JAG1 0 -0.260 0.070
MIB1 0 0.710 -1.060 0.258
GLI3 0 -0.980 1.650
PRPF19 0 -0.460 0.190 -0.179 -0.151 -0.246
HES1 0 -0.940 0.860
ID2 0 -0.080 -0.630
CDK5RAP2 0 -0.900 1.740 -0.181 0.284
HMG20A 0 0.790 -0.810 1.137 0.647 0.779 -0.386 0.078
APP 0 0.100 -0.260 0.285
ITGB1 0 0.390 -0.650 0.101 -0.036
ISL2 0 0.170 -0.540 0.032
ID4 0 0.670 -0.690
FOXL1 0 0.560 -0.350 -1.217 -0.424 0.659
ZHX2 0 -0.240 0.680 -0.053 0.857
CALR 0 -1.300 2.220 0.480 0.054
SOX2 0 -0.250 0.870
TTC3 0 -0.630 0.140
PBX1 0 -0.600 0.280
PBX1 0 -0.600 0.280 -0.186 -0.124

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
APP Ubiquitylation K751 -1.778 -1.280 _HLSK(gl)M(ox)QQNGYENPTYK_
ASPM Phosphorylation S392 -0.089 _DNYGLNQDLESESVNPILS(ph)PNQFLK_
ASPM Phosphorylation S425 -0.509 _VPLSNENSQVPQS(ph)PEDWRK_
ASPM Phosphorylation S605 -0.742 -0.350 _IHFS(ph)PSEPK_
ASPM Ubiquitylation K626 -1.228 _NVTTPISK(gl)R_
ASPM Ubiquitylation K748 -0.358 _APTK(gl)EEMSLR_
ASPM Ubiquitylation K1537 -0.627 _TNYLQK(gl)R_
ASPM Ubiquitylation K1822 -1.087 _QLIK(gl)QQSIAALK_
ASPM Ubiquitylation K1875 -1.319 _TK(gl)AAVISLQSAYR_
ASPM Ubiquitylation K2002 -0.273 _AALLIQK(gl)YYR_
ASPM Ubiquitylation K2021 -1.473 _TK(gl)AAVVTLQSAYR_
ASPM Ubiquitylation K2045 -1.343 _IKDCNK(gl)AAVTIQSK_
ASPM Ubiquitylation K2053 -1.087 -0.931 _AAVTIQSK(gl)YR_
ASPM Ubiquitylation K2227 -1.323 _YWAMK(gl)ER_
ASPM Ubiquitylation K2358 -0.665 _YQALK(gl)QASVVIQQQYQANR_
ASPM Ubiquitylation K2619 -0.325 _ETCVQAGFQDMNIKK(gl)_
ASPM Ubiquitylation K2823 -0.942 _AAVTIQK(gl)AFCR_
ASPM Ubiquitylation K2933 -1.382 _FQEIK(gl)NSTIK_
BMP7 Ubiquitylation K178 -0.107 _IYK(gl)DYIR_
CALR Ubiquitylation K48 0.703 _SDFGK(gl)FVLSSGK_
CALR Ubiquitylation K153 -0.924 0.619 _GK(gl)NVLINK_
CALR Ubiquitylation K159 -1.004 0.381 _NVLINK(gl)DIR_
CDK5RAP2 Ubiquitylation K489 -0.006 _HLTESTNQK(gl)DVLLQK_
CDK5RAP2 Phosphorylation S697 -0.007 _LAS(ph)T(ph)EQTELLASK_
CDK5RAP2 Phosphorylation T698 -0.007 _LAS(ph)T(ph)EQTELLASK_
CDK5RAP2 Ubiquitylation K943 -0.252 _SRLPILIK(gl)_
CDK5RAP2 Phosphorylation S1074 1.217 0.953 _ENPEDVLS(ph)PTSVATYLSSK_
CDK5RAP2 Phosphorylation S1238 0.477 0.111 _DLS(ph)PPRYDSLVQSQAR_
CDK5RAP2 Phosphorylation S1350 -1.016 -0.606 _IEEDNLTYQHLLPES(ph)PEPSASHALSDYETSEK_
CDK5RAP2 Phosphorylation T1885 -0.869 _GNLELRPGGAHPGT(ph)CSPSRPGS_
CDK5RAP2 Phosphorylation S1887 -0.612 -1.053 _GNLELRPGGAHPGTCS(ph)PSRPGS_
CDK5RAP2 Phosphorylation S1889 -0.312 _GNLELRPGGAHPGTCSPS(ph)RPGS_
CTDSP1 Ubiquitylation K190 -0.115 _GNYVK(gl)DLSR_
FOXL1 Phosphorylation S6 0.325 0.055 _YS(ph)VSSPNSLGVVPYLGGEQSYYR_
FOXL1 Phosphorylation S235 -1.239 _TENGTCPS(ph)PPQPLS(ph)PAAALGSGSAAAVPK_
FOXL1 Phosphorylation S241 -1.239 _TENGTCPS(ph)PPQPLS(ph)PAAALGSGSAAAVPK_
FOXL1 Phosphorylation S259 -0.376 -0.198 _IES(ph)PDSSSSSLSSGSSPPGSLPSAR_
FOXL1 Phosphorylation S320 0.313 0.178 _GS(ph)PQSAAAELSSGLLASAAASSR_
FOXL1 Phosphorylation S323 0.347 _GSPQS(ph)AAAELSSGLLASAAASSR_
FOXL1 Ubiquitylation K554 -0.030 0.013 _TSGAFVYDCSK(gl)F_
GLI3 Phosphorylation S664 -0.582 -0.252 _S(ph)PGRPTQGALGEQQDLSNTTSK_
HES1 Ubiquitylation K66 0.212 _TLILDALK(gl)K_
HES1 Ubiquitylation K67 0.212 _TLILDALK(gl)K_
HES1 Ubiquitylation K109 -0.891 _AQMTAALSTDPSVLGK(gl)YR_
HMG20A Phosphorylation S105 0.508 0.515 _S(ph)PLTGYVR_
HMG20A Phosphorylation T108 0.498 _DSNAPKSPLT(ph)GYVR_
HMG20A Ubiquitylation K255 1.175 _NAALQK(gl)HVESMR_
ID2 Phosphorylation S14 -0.139 _NS(ph)LSDHSLGISR_
ID4 Phosphorylation S5 -0.437 -0.234 _AVS(ph)PVRPSGR_
ISL2 Phosphorylation S157 -0.640 -0.776 _S(ph)PGPLPGAR_
ISL2 Ubiquitylation K201 -0.430 -1.275 _TVLNEK(gl)QLHTLR_
ISL2 Phosphorylation S279 0.101 _TSLQGLTGTPLVAGS(ph)PIR_
ITGB1 Ubiquitylation K774 0.402 _MNAK(gl)WDTGENPIYK_
ITGB1 Ubiquitylation K784 -0.172 0.350 _WDTGENPIYK(gl)SAVTTVVNPK_
ITGB1 Ubiquitylation K794 0.755 0.604 _SAVTTVVNPK(gl)YEGK_
JAG1 Ubiquitylation K1142 -0.783 _HGANTVPIKDYENK(gl)_
MED1 Phosphorylation S664 3.368 _DNPAQDFSTLYGSS(ph)PLER_
MED1 Phosphorylation S771 -1.422 _LSS(ph)SDSIGPDVTDILSDIAEEASKLPSTSDDCPAIGTPLR_
MED1 Phosphorylation T1051 -1.201 -1.247 _SQT(ph)PPGVATPPIPK_
MED1 Phosphorylation T1057 -1.294 _SQT(ph)PPGVAT(ph)PPIPK_
MED1 Phosphorylation S1155 0.689 _NSSQSGGKPGS(ph)SPITK_
MED1 Phosphorylation S1156 0.829 1.055 _NSSQSGGKPGSS(ph)PITK_
MED1 Phosphorylation S1192 -0.792 _PSSLM(ox)NPSLSKPNIS(ph)PSHSRPPGGSDK_
MED1 Phosphorylation S1223 1.061 1.013 _AKS(ph)PISSGSGGSHM(ox)SGTSSSSGM(ox)K_
MED1 Phosphorylation S1433 -0.191 _NYGS(ph)PLISGSTPK_
MIB1 Ubiquitylation K28 -0.465 -1.379 _WGK(gl)QDGGEGHVGTVR_
MIB1 Ubiquitylation K222 -0.025 -0.938 _CVQDAK(gl)GGSFYR_
MIB1 Ubiquitylation K420 -1.942 -2.115 _LSQLLK(gl)K_
MIB1 Ubiquitylation K421 -1.850 _LSQLLKK(gl)_
MIB1 Ubiquitylation K485 -1.697 _LLLK(gl)QNVDVEAEDKDGDR_
MIB1 Ubiquitylation K726 -2.735 -2.946 _QLQDMQDVGK(gl)VDAAWEPSK_
MIB1 Ubiquitylation K749 -2.124 _NTLIMGLGTQGAEK(gl)K_
MIB1 Ubiquitylation K750 -2.385 -2.133 _NTLIMGLGTQGAEKK(gl)_
MIB1 Ubiquitylation K787 -3.370 _KGQSPLDLCPDPNLCK(gl)ALAK_
MIB1 Ubiquitylation K791 -3.063 -2.513 _GQSPLDLCPDPNLCKALAK(gl)_
MIB1 Ubiquitylation K796 -3.011 _EK(gl)VSGQVGSR_
MIB1 Ubiquitylation K854 -0.986 _CLICK(gl)EQVQSR_
MIB1 Ubiquitylation K872 -2.513 -2.977 _TKIEECVVCSDK(gl)K_
MIB1 Ubiquitylation K873 -2.513 _IEECVVCSDK(gl)K_
PBX1 Ubiquitylation K164 -0.541 _SK(gl)LAQIR_
PBX1 Ubiquitylation K195 -1.614 _TRPISPK(gl)EIER_
PBX2 Ubiquitylation K164 -0.541 _SK(gl)LAQIR_
PRPF19 Ubiquitylation K122 0.200 _LTK(gl)EVTAAR_
PRPF19 Ubiquitylation K261 -1.023 0.257 _SSEQILATLK(gl)GHTK_
REST Ubiquitylation K280 0.406 _VYTCGK(gl)CNYFSDR_
REST Phosphorylation S864 -3.456 _ESVSTEDLSPPS(ph)PPLPK_
RHOA Ubiquitylation K6 0.708 _K(gl)KLVIVGDGACGK_
RHOA Ubiquitylation K7 0.708 _K(gl)KLVIVGDGACGK_
RHOA Ubiquitylation K118 -0.408 _HFCPNVPIILVGNK(gl)K_
RHOA Ubiquitylation K119 -0.408 _HFCPNVPIILVGNK(gl)K_
RHOA Ubiquitylation K135 -0.528 -0.796 _MK(gl)QEPVKPEEGRDMANR_
RHOA Ubiquitylation K162 0.345 0.453 _IGAFGYMECSAK(gl)TK_
SOX2 Phosphorylation S251 0.157 -0.109 _SEASSS(ph)PPVVTSSSHSR_
TTC3 Ubiquitylation K470 -1.268 _NILEK(gl)QFSK_


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