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Query: MIB1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MIB1 0 0.233 0.710 -1.060 0.258

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MIB1 Ubiquitylation K222 -0.025 -0.938 _CVQDAK(gl)GGSFYR_
MIB1 Ubiquitylation K854 -0.986 _CLICK(gl)EQVQSR_
MIB1 Ubiquitylation K28 -0.465 -1.379 _WGK(gl)QDGGEGHVGTVR_
MIB1 Ubiquitylation K421 -1.850 _LSQLLKK(gl)_
MIB1 Ubiquitylation K420 -1.942 -2.115 _LSQLLK(gl)K_
MIB1 Ubiquitylation K749 -2.124 _NTLIMGLGTQGAEK(gl)K_
MIB1 Ubiquitylation K750 -2.385 -2.133 _NTLIMGLGTQGAEKK(gl)_
MIB1 Ubiquitylation K791 -3.063 -2.513 _GQSPLDLCPDPNLCKALAK(gl)_
MIB1 Ubiquitylation K726 -2.735 -2.946 _QLQDMQDVGK(gl)VDAAWEPSK_
MIB1 Ubiquitylation K872 -2.513 -2.977 _TKIEECVVCSDK(gl)K_
MIB1 Ubiquitylation K796 -3.011 _EK(gl)VSGQVGSR_
MIB1 Ubiquitylation K485 -1.697 _LLLK(gl)QNVDVEAEDKDGDR_
MIB1 Ubiquitylation K787 -3.370 _KGQSPLDLCPDPNLCK(gl)ALAK_
MIB1 Ubiquitylation K873 -2.513 _IEECVVCSDK(gl)K_

Background Information for MIB1:


Pubmed-MIB1 »
Uniprot-MIB1 »
Biogrid-MIB1 »
ProteomicsDB-MIB1 »

Tumorportal-MIB1 »
COSMIC-MIB1 »
GenomeRNAi-MIB1 »
Genecards-MIB1


Protein-protein Interactions for MIB1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ANKRD26 Cat. description Hein, Mann, Cell 2015
Category members IP bait AZI1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCDC14 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDK5RAP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP120 Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP135 Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP72 Cat. description Hein, Mann, Cell 2015
Category members IP bait DYNLL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait FGFR1OP Cat. description Hein, Mann, Cell 2015
Category members IP bait LRRCC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAPRE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MIB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NEDD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait OFD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PCM1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PCNT Cat. description Hein, Mann, Cell 2015
Category members IP bait PER3 Cat. description Hein, Mann, Cell 2015
Category members IP bait PRKAR2A Cat. description Hein, Mann, Cell 2015
Category members IP bait PRKAR2B Cat. description Hein, Mann, Cell 2015
Category members IP bait SDCCAG8 Cat. description Hein, Mann, Cell 2015
Category members IP bait ANKRD55 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CHRNA3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EPN3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM171B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FSD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LPXN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LRRCC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MIB1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_ZZ IPR000433 0.01
Category members Znf_RING IPR001841 0
Category members Ankyrin_rpt IPR002110 0
Category members Mib_Herc2 IPR010606 0
Category members Ankyrin_rpt-contain_dom IPR020683 0


Protein complexes (CORUM database) featuring MIB1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MIB1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0031965 nuclear membrane Database 2.59
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0005813 centrosome Database 0.75
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members Pathway Pathway_117 REACTOME_SIGNALING_BY_NOTCH 0 0.33
Category members Pathway Pathway_849 PID_NOTCH_PATHWAY 0 0.29
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members Pathway Pathway_789 REACTOME_SIGNALING_BY_NOTCH1 0 0.22
Category members GO Category GO:0001701 in utero embryonic development Database 0.2
Category members GO Category GO:0001947 heart looping Database 0.08
Category members GO Category GO:0016567 protein ubiquitination Database 0.07
Category members GO Category GO:0007219 Notch signaling pathway Database 0.05
Category members GO Category GO:0045665 negative regulation of neuron differentiation Database 0.04
Category members Pathway Pathway_831 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS 0 0
Category members Disease phenotype Left_ventricular_noncompaction Left ventricular noncompaction Database 0
Category members GO Category GO:0001568 blood vessel development Database 0
Category members GO Category GO:0001756 somitogenesis Database 0
Category members GO Category GO:0001841 neural tube formation Database 0
Category members GO Category GO:0007507 heart development Database 0
Category members GO Category GO:0014069 postsynaptic density Database 0
Category members GO Category GO:0031410 cytoplasmic vesicle Database 0
Category members GO Category GO:0045807 positive regulation of endocytosis Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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