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REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS
(Pathway_831)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
RPS27A 4 -1.330 2.560 -0.309 0.131 -0.009
UBA52 3 -1.260 2.180 -0.309 0.131 -0.009
UBA52 3 -1.260 2.180
CNTN1 1 -1.210 1.700 -0.706 2.148
APH1B 1 -1.760 3.070
ARRB2 1 2.000 -1.160 -0.340 0.096 0.051 -1.604
PSEN2 1 -1.820 3.280
MIB2 1 1.120 -0.830
PSEN1 0 0.930 -1.110
JAG1 0 -0.260 0.070
MIB1 0 0.710 -1.060 0.258
NUMB 0 0.310 0.050
ARRB1 0 0.960 -0.620
ADAM10 0 1.400 -1.040 -0.111 0.009
ADAM17 0 0.520 -0.620
NCSTN 0 -1.540 2.100 0.618 0.379
JAG2 0 -0.170 0.020
DNER 0 -0.450 -0.080
PSENEN 0 -0.550 0.740

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ADAM10 Ubiquitylation K721 -2.406 _LPPPKPLPGTLK(gl)R_
ADAM17 Phosphorylation S791 -0.594 0.152 _S(ph)FEDLTDHPVTR_
APH1B Ubiquitylation K102 -0.148 _ASEGLK(gl)SINPGETAPSMR_
ARRB1 Phosphorylation S412 0.138 0.253 _GMKDDKEEEEDGTGS(ph)PQLNNR_
ARRB2 Ubiquitylation K199 -1.933 _VQFAPEK(gl)PGPQPSAETTR_
DNER Ubiquitylation K733 -0.847 _PLVTLIK(gl)_
JAG1 Ubiquitylation K1142 -0.783 _HGANTVPIKDYENK(gl)_
JAG2 Ubiquitylation K76 1.283 _VCLK(gl)EYQAK_
JAG2 Phosphorylation T1155 -0.335 -0.737 _NFT(ph)PPPR_
JAG2 Ubiquitylation K1200 0.117 _FLSHK(gl)FTK_
MIB1 Ubiquitylation K28 -0.465 -1.379 _WGK(gl)QDGGEGHVGTVR_
MIB1 Ubiquitylation K222 -0.025 -0.938 _CVQDAK(gl)GGSFYR_
MIB1 Ubiquitylation K420 -1.942 -2.115 _LSQLLK(gl)K_
MIB1 Ubiquitylation K421 -1.850 _LSQLLKK(gl)_
MIB1 Ubiquitylation K485 -1.697 _LLLK(gl)QNVDVEAEDKDGDR_
MIB1 Ubiquitylation K726 -2.735 -2.946 _QLQDMQDVGK(gl)VDAAWEPSK_
MIB1 Ubiquitylation K749 -2.124 _NTLIMGLGTQGAEK(gl)K_
MIB1 Ubiquitylation K750 -2.385 -2.133 _NTLIMGLGTQGAEKK(gl)_
MIB1 Ubiquitylation K787 -3.370 _KGQSPLDLCPDPNLCK(gl)ALAK_
MIB1 Ubiquitylation K791 -3.063 -2.513 _GQSPLDLCPDPNLCKALAK(gl)_
MIB1 Ubiquitylation K796 -3.011 _EK(gl)VSGQVGSR_
MIB1 Ubiquitylation K854 -0.986 _CLICK(gl)EQVQSR_
MIB1 Ubiquitylation K872 -2.513 -2.977 _TKIEECVVCSDK(gl)K_
MIB1 Ubiquitylation K873 -2.513 _IEECVVCSDK(gl)K_
MIB2 Phosphorylation S366 1.337 0.856 _RVS(ph)ADSQPFQHGDK_
MIB2 Ubiquitylation K459 3.313 _VIGDLDTVK(gl)R_
MIB2 Ubiquitylation K899 -0.234 -0.560 _VLK(gl)ALQGCAQR_
NCSTN Ubiquitylation K110 1.107 _DLMEK(gl)LK_
NUMB Ubiquitylation K63 0.281 _GMHICEDAVK(gl)R_
NUMB Phosphorylation T436 0.878 _RT(ph)PSEADRWLEEVSK_
PSEN1 Phosphorylation S313 0.844 _VSKNS(ph)KYNAESTER_
PSEN1 Ubiquitylation K314 0.016 0.414 _NSK(gl)YNAESTER_
PSEN1 Phosphorylation S366 -0.340 0.055 _AAVQELSS(ph)SILAGEDPEER_
PSEN1 Phosphorylation S367 0.005 0.066 _AAVQELSSS(ph)ILAGEDPEER_
PSEN2 Phosphorylation S58 -0.112 -0.130 _TSLM(ox)SAES(ph)PTPR_
PSENEN Ubiquitylation K11 0.476 _VSNEEK(gl)LNLCR_
RPS27A Ubiquitylation K6 1.066 0.995 _MQIFVK(gl)TLTGK_
RPS27A Ubiquitylation K11 -0.488 -0.081 _TLTGK(gl)TITLEVEPSDTIENVKAK(gl)_
RPS27A Ubiquitylation K27 -0.882 -0.159 _TLTGK(gl)TITLEVEPSDTIENVK(gl)AK_
RPS27A Ubiquitylation K29 -1.087 -1.029 _AK(gl)IQDK(gl)EGIPPDQQR_
RPS27A Ubiquitylation K33 -0.736 -0.407 _IQDK(gl)EGIPPDQQR_
RPS27A Ubiquitylation K48 -0.062 0.315 _LIFAGK(gl)QLEDGRTLSDYNIQK_
RPS27A Phosphorylation S57 1.909 0.548 _TLS(ph)DYNIQK_
RPS27A Ubiquitylation K63 0.276 0.299 _TLSDYNIQK(gl)ESTLHLVLR_
RPS27A Ubiquitylation K99 0.109 2.111 _VK(gl)LAVLK_
RPS27A Ubiquitylation K104 0.674 2.102 _LAVLK(gl)YYK_
RPS27A Ubiquitylation K107 2.949 3.611 _YYK(gl)VDENGK(gl)ISR_
RPS27A Ubiquitylation K113 1.572 3.672 _YYK(gl)VDENGK(gl)ISR_
RPS27A Ubiquitylation K152 4.747 4.970 _CCLTYCFNK(gl)PEDK_
RPS27A Ubiquitylation K156 4.809 _CCLTYCFNKPEDK(gl)_
UBA52 Ubiquitylation K6 1.066 0.995 _MQIFVK(gl)TLTGK_
UBA52 Ubiquitylation K11 -0.488 -0.081 _TLTGK(gl)TITLEVEPSDTIENVKAK(gl)_
UBA52 Ubiquitylation K27 -0.882 -0.159 _TLTGK(gl)TITLEVEPSDTIENVK(gl)AK_
UBA52 Ubiquitylation K29 -1.087 -1.029 _AK(gl)IQDK(gl)EGIPPDQQR_
UBA52 Ubiquitylation K33 -0.736 -0.407 _IQDK(gl)EGIPPDQQR_
UBA52 Ubiquitylation K48 -0.062 0.315 _LIFAGK(gl)QLEDGRTLSDYNIQK_
UBA52 Phosphorylation S57 1.909 0.548 _TLS(ph)DYNIQK_
UBA52 Ubiquitylation K63 0.276 0.299 _TLSDYNIQK(gl)ESTLHLVLR_
UBA52 Ubiquitylation K93 0.181 2.418 _YNCDK(gl)MICR_
UBA52 Ubiquitylation K99 0.109 2.111 _VK(gl)LAVLK_
UBA52 Ubiquitylation K104 0.674 2.102 _LAVLK(gl)YYK_
UBA52 Ubiquitylation K107 2.949 3.611 _YYK(gl)VDENGK(gl)ISR_
UBA52 Ubiquitylation K113 1.572 3.672 _YYK(gl)VDENGK(gl)ISR_
UBA52 Ubiquitylation K152 4.747 4.970 _CCLTYCFNK(gl)PEDK_
UBA52 Ubiquitylation K156 4.809 _CCLTYCFNKPEDK(gl)_


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