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Query: BMP7

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
BMP7 0 -0.107

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
BMP7 Ubiquitylation K178 -0.107 _IYK(gl)DYIR_

Background Information for BMP7:


Pubmed-BMP7 »
Uniprot-BMP7 »
Biogrid-BMP7 »
ProteomicsDB-BMP7 »

Tumorportal-BMP7 »
COSMIC-BMP7 »
GenomeRNAi-BMP7 »
Genecards-BMP7


Protein-protein Interactions for BMP7
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BMP7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DKKL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NAAA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait OLFM2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait OLFM4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PTPRK Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLAMF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TAZ Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRAC Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in BMP7
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Cystine-knot_cytokine IPR029034 0.52
Category members TGF-b_C IPR001839 0.35
Category members TGF-b_N IPR001111 0.17
Category members Inhibin_asu IPR002405 0


Protein complexes (CORUM database) featuring BMP7
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring BMP7
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005576 extracellular region Database 10.9
Category members GO Category GO:0005615 extracellular space Database 4.72
Category members GO Category GO:0008083 growth factor activity Database 2.34
Category members Pathway Pathway_448 KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION 0 2.05
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0005125 cytokine activity Database 1.06
Category members GO Category GO:0045786 negative regulation of cell cycle Database 0.93
Category members GO Category GO:0010942 positive regulation of cell death Database 0.82
Category members GO Category GO:0042326 negative regulation of phosphorylation Database 0.5
Category members GO Category GO:0031012 extracellular matrix Database 0.45
Category members GO Category GO:0045597 positive regulation of cell differentiation Database 0.45
Category members GO Category GO:0030855 epithelial cell differentiation Database 0.28
Category members GO Category GO:0008285 negative regulation of cell proliferation Database 0.28
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0008201 heparin binding Database 0.27
Category members GO Category GO:0030198 extracellular matrix organization Database 0.26
Category members GO Category GO:0043065 positive regulation of apoptotic process Database 0.26
Category members GO Category GO:0060686 negative regulation of prostatic bud formation Database 0.23
Category members GO Category GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation Database 0.23
Category members GO Category GO:0030509 BMP signaling pathway Database 0.2
Category members GO Category GO:0007389 pattern specification process Database 0.18
Category members GO Category GO:0034504 protein localization to nucleus Database 0.15
Category members Pathway Pathway_893 KEGG_TGF_BETA_SIGNALING_PATHWAY 0 0.14
Category members GO Category GO:0007411 axon guidance Database 0.13
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0034116 positive regulation of heterotypic cell-cell adhesion Database 0.13
Category members GO Category GO:0001707 mesoderm formation Database 0.11
Category members GO Category GO:0045839 negative regulation of mitosis Database 0.08
Category members GO Category GO:0045665 negative regulation of neuron differentiation Database 0.04
Category members GO Category GO:0032088 negative regulation of NF-kappaB transcription factor activity Database 0.04
Category members GO Category GO:0042347 negative regulation of NF-kappaB import into nucleus Database 0.04
Category members GO Category GO:0070487 monocyte aggregation Database 0.04
Category members Pathway Pathway_1151 KEGG_HEDGEHOG_SIGNALING_PATHWAY 0 0.04
Category members GO Category GO:0048646 anatomical structure formation involved in morphogenesis Database 0.04
Category members GO Category GO:0048596 embryonic camera-type eye morphogenesis Database 0.01
Category members GO Category GO:0001656 metanephros development Database 0
Category members Pathway Pathway_1133 PID_BMP_PATHWAY 0 0
Category members Pathway Pathway_1209 PID_ALK2_PATHWAY 0 0
Category members Pathway Pathway_872 BIOCARTA_ALK_PATHWAY 0 0
Category members GO Category GO:0001501 skeletal system development Database 0
Category members GO Category GO:0001503 ossification Database 0
Category members GO Category GO:0001654 eye development Database 0
Category members GO Category GO:0001657 ureteric bud development Database 0
Category members GO Category GO:0001822 kidney development Database 0
Category members GO Category GO:0001823 mesonephros development Database 0
Category members GO Category GO:0001837 epithelial to mesenchymal transition Database 0
Category members GO Category GO:0007435 salivary gland morphogenesis Database 0
Category members GO Category GO:0009880 embryonic pattern specification Database 0
Category members GO Category GO:0009887 organ morphogenesis Database 0
Category members GO Category GO:0010664 negative regulation of striated muscle cell apoptotic process Database 0
Category members GO Category GO:0010800 positive regulation of peptidyl-threonine phosphorylation Database 0
Category members GO Category GO:0016358 dendrite development Database 0
Category members GO Category GO:0030326 embryonic limb morphogenesis Database 0
Category members GO Category GO:0030501 positive regulation of bone mineralization Database 0
Category members GO Category GO:0031988 membrane-bounded vesicle Database 0
Category members GO Category GO:0032355 response to estradiol Database 0
Category members GO Category GO:0033280 response to vitamin D Database 0
Category members GO Category GO:0035239 tube morphogenesis Database 0
Category members GO Category GO:0040007 growth Database 0
Category members GO Category GO:0042325 regulation of phosphorylation Database 0
Category members GO Category GO:0042475 odontogenesis of dentin-containing tooth Database 0
Category members GO Category GO:0043401 steroid hormone mediated signaling pathway Database 0
Category members GO Category GO:0043407 negative regulation of MAP kinase activity Database 0
Category members GO Category GO:0043434 response to peptide hormone Database 0
Category members GO Category GO:0045666 positive regulation of neuron differentiation Database 0
Category members GO Category GO:0045669 positive regulation of osteoblast differentiation Database 0
Category members GO Category GO:0045746 negative regulation of Notch signaling pathway Database 0
Category members GO Category GO:0048468 cell development Database 0
Category members GO Category GO:0048593 camera-type eye morphogenesis Database 0
Category members GO Category GO:0048754 branching morphogenesis of an epithelial tube Database 0
Category members GO Category GO:0048762 mesenchymal cell differentiation Database 0
Category members GO Category GO:0048812 neuron projection morphogenesis Database 0
Category members GO Category GO:0050768 negative regulation of neurogenesis Database 0
Category members GO Category GO:0051216 cartilage development Database 0
Category members GO Category GO:0060272 embryonic skeletal joint morphogenesis Database 0
Category members GO Category GO:0060393 regulation of pathway-restricted SMAD protein phosphorylation Database 0
Category members GO Category GO:0060395 SMAD protein signal transduction Database 0
Category members GO Category GO:0060445 branching involved in salivary gland morphogenesis Database 0
Category members GO Category GO:0060485 mesenchyme development Database 0
Category members GO Category GO:0060548 negative regulation of cell death Database 0
Category members GO Category GO:0060687 regulation of branching involved in prostate gland morphogenesis Database 0
Category members GO Category GO:0071456 cellular response to hypoxia Database 0


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