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negative regulation of cell cycle
(GO:0045786)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
PPP1R13B 1 0.760 -0.700 -0.399 -0.481
PPP1R13B 1 0.760 -0.700
HDAC1 1 -1.980 4.450
HDAC1 1 -1.980 4.450 -0.122 0.307 0.969 0.094 0.191
ETS1 1 1.070 -0.650
TP53BP2 1 1.060 -0.800 -0.399 -0.481
PDCD4 1 -0.500 1.310 0.149
PDCD4 1 -0.500 1.310
THAP5 1 1.120 -0.910
THAP5 1 2.630 -1.100
HDAC2 1 -2.390 4.970
HDAC2 1 -2.390 4.970 0.187 -0.007 0.825
RUNX3 0 -0.550 0.450
BMP7 0
TGFB1 0 -0.550 1.050
CDK6 0 -0.190 0.160
CDK6 0 -0.190 0.160 -0.510 0.013
TAF6 0 -0.130 -0.310 -0.213 -1.092 0.653 0.100 0.301
CREB3 0 0.180 -0.820
GATA3 0 0.000 -0.660
RNF167 0 0.270 -0.510
GMNN 0 0.620 -1.000
HTRA2 0 1.220 -0.530 0.602 -0.023 1.287
ZBTB17 0 0.670 -0.540
ILKAP 0 -0.310 -0.170 -0.420 0.461
MEN1 0 1.080 -1.150 0.101 0.684 -0.063
MEN1 0 1.080 -1.150 0.395
MEN1 0 1.080 -1.150
RB1 0 1.180 -1.070 0.429 0.755
RB1 0 1.180 -1.070
RHOB 0 0.130 -0.210
HPGD 0 -0.750 0.620
CASP3 0 0.570 -0.390
CDK5 0 -1.100 1.740 -0.236 1.063 0.312
HDAC3 0 -0.790 1.070
ALOX15B 0

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ALOX15B Ubiquitylation K214 0.144 _SLNEMK(gl)R_
BMP7 Ubiquitylation K178 -0.107 _IYK(gl)DYIR_
CASP3 Ubiquitylation K11 -0.053 -0.687 _(ac)MENTENSVDSK(gl)SIK_
CASP3 Ubiquitylation K14 -0.455 -0.687 _SIK(gl)NLEPK_
CASP3 Ubiquitylation K57 -0.304 -1.817 _NFHK(gl)STGMTSR_
CASP3 Ubiquitylation K82 -0.268 -0.605 _NLK(gl)YEVR_
CDK5 Ubiquitylation K56 0.606 0.237 _EICLLK(gl)ELK_
CDK6 Ubiquitylation K3 0.121 0.039 _(ac)MEK(gl)DGLCR_
CDK6 Phosphorylation S236 0.095 _QDDS(ph)PSGASYGQDYDLS(ph)PSR_
CDK6 Phosphorylation S249 0.095 _QDDS(ph)PSGASYGQDYDLS(ph)PSR_
CDK6 Phosphorylation S385 0.649 _HSSIS(ph)PVRLPLNSSLGAELSR_
CDK6 Phosphorylation S420 0.004 -0.202 _ES(ph)KGSPVFLPR_
CDK6 Phosphorylation S423 -0.155 -0.297 _GS(ph)PVFLPR_
CDK6 Phosphorylation T514 0.364 0.570 _DSKPIALKEEIVT(ph)PK_
CDK6 Phosphorylation S681 -2.532 -2.051 _HLLTDLPLPPELPGGDLS(ph)PPDS(ph)PEPK_
CDK6 Phosphorylation S685 -2.729 _HLLTDLPLPPELPGGDLS(ph)PPDS(ph)PEPK_
CDK6 Phosphorylation T692 -0.765 -1.849 _AIT(ph)PPQQPYK_
CDK6 Phosphorylation S1082 -1.661 -0.980 _KETTSGTSTEPVKNS(ph)SPAPPQPAPGK_
CDK6 Phosphorylation S1083 -1.093 -1.330 _NSS(ph)PAPPQPAPGK_
CDK6 Phosphorylation T1244 -0.956 _RT(ph)PTMPQEEAAACPPHILPPEK_
CREB3 Ubiquitylation K176 -0.114 _TEEQILK(gl)R_
ETS1 Ubiquitylation K416 7.479 _MNYEK(gl)LSR_
ETS1 Ubiquitylation K427 -0.895 _YYYDK(gl)NIIHK_
GATA3 Phosphorylation S162 -1.195 -0.563 _DVS(ph)PDPSLSTPGSAGSAR_
GMNN Ubiquitylation K50 -0.622 -0.151 _ENELSAGLSK(gl)R_
GMNN Phosphorylation S63 0.028 -0.793 _NDHLTSTTS(ph)SPGVIVPESSENK_
HDAC1 Ubiquitylation K50 0.036 _K(gl)MEIYRPHK_
HDAC1 Ubiquitylation K66 -0.593 _ANAEEMTK(gl)YHSDDYIK_
HDAC1 Ubiquitylation K74 0.620 -1.473 _YHSDDYIK(gl)FLR_
HDAC1 Ubiquitylation K89 0.749 -0.241 _SIRPDNMSEYSK(gl)QMQR_
HDAC1 Phosphorylation S393 -1.133 -1.144 _M(ox)LPHAPGVQM(ox)QAIPEDAIPEES(ph)GDEDEDDPDKR_
HDAC1 Phosphorylation S409 1.326 1.144 _ISICS(ph)SDKR_
HDAC1 Phosphorylation S410 1.326 1.144 _ISICS(ph)SDKR_
HDAC1 Ubiquitylation K412 0.642 -0.744 _ISICSSDK(gl)R_
HDAC2 Ubiquitylation K50 0.036 _K(gl)MEIYRPHK_
HDAC2 Ubiquitylation K67 -0.467 _ATAEEMTK(gl)YHSDEYIK_
HDAC2 Ubiquitylation K89 0.749 -0.241 _SIRPDNMSEYSK(gl)QMQR_
HDAC2 Ubiquitylation K284 0.749 _GHAK(gl)CVEVVK_
HDAC2 Phosphorylation S394 -0.865 -0.997 _M(ox)LPHAPGVQM(ox)QAIPEDAVHEDS(ph)GDEDGEDPDKR_
HDAC2 Phosphorylation S422 0.482 0.781 _IACDEEFS(ph)DSEDEGEGGR_
HDAC3 Phosphorylation S424 -0.354 _GPEENYSRPEAPNEFYDGDHDNDKES(ph)DVEI_
HTRA2 Ubiquitylation K237 -1.868 -0.270 _IQTK(gl)EPLPTLPLGR_
ILKAP Phosphorylation S13 -0.127 -0.533 _(ac)M(ox)DLFGDLPEPERS(ph)PRPAAGK_
MEN1 Ubiquitylation K8 -1.132 0.088 _AAQK(gl)TLFPLR_
MEN1 Phosphorylation S218 -0.820 _RES(ph)KPEEPPPPK_
PDCD4 Phosphorylation S76 1.091 0.816 _GDS(ph)VSDSGSDALR_
PDCD4 Phosphorylation T93 -0.214 0.036 _SGLTVPT(ph)SPK_
PDCD4 Phosphorylation S94 -0.407 -0.022 _SGLTVPTS(ph)PK_
PDCD4 Ubiquitylation K242 1.242 _SFDK(gl)LLK_
PDCD4 Ubiquitylation K245 -0.529 _LLK(gl)DLPELALDTPR_
PDCD4 Ubiquitylation K309 1.505 _ATVLLSMSKGGK(gl)_
PDCD4 Phosphorylation S457 0.751 0.699 _RFVS(ph)EGDGGR_
PPP1R13B Ubiquitylation K102 0.149 _SQDPSLK(gl)R_
PPP1R13B Ubiquitylation K152 0.224 _QQQQIEAQQQLLATK(gl)EQR_
PPP1R13B Ubiquitylation K224 -0.390 _LVEEIEQMNNLFQQK(gl)QR_
PPP1R13B Ubiquitylation K234 -0.113 _ELVLAVSK(gl)VEELTR_
PPP1R13B Ubiquitylation K247 0.193 _VDQLSQQLEDLKK(gl)_
PPP1R13B Ubiquitylation K268 -0.429 _LYK(gl)ELQLR_
PPP1R13B Ubiquitylation K269 -0.833 _LTGPAAVELK(gl)R_
PPP1R13B Ubiquitylation K283 -0.866 _NKLNQEQNAK(gl)LQQQR_
PPP1R13B Ubiquitylation K288 -0.100 -0.011 _NQLNQEQNSK(gl)LQQQK_
PPP1R13B Ubiquitylation K293 -0.061 _LQQQK(gl)ELLNKR_
PPP1R13B Ubiquitylation K303 -0.302 _NSEVAVMDK(gl)R_
PPP1R13B Ubiquitylation K322 -2.045 _AALQQK(gl)ENLPVSSDGNLPQQAASAPSR_
PPP1R13B Phosphorylation S480 0.458 0.944 _NQS(ph)SEDILR_
PPP1R13B Phosphorylation S556 1.443 1.433 _VLLS(ph)PSIPSVGQDQTLSPGSK_
PPP1R13B Phosphorylation S569 1.774 _VLLS(ph)PSIPSVGQDQTLS(ph)PGSK_
PPP1R13B Phosphorylation S698 -0.309 -0.362 _IPRPLS(ph)PTK_
PPP1R13B Phosphorylation T700 -0.449 -0.429 _IPRPLSPT(ph)K_
PPP1R13B Phosphorylation S710 -0.910 -0.515 _RSS(ph)ITEPEGPGGPNIQK_
PPP1R13B Phosphorylation S737 -0.172 -0.748 _RSS(ph)ITEPEGPNGPNIQK_
RB1 Phosphorylation S69 -3.602 -3.397 _TAATAAAAAAEPPAPPPPPPPEEDPEQDS(ph)GPEDLPLVR_
RB1 Ubiquitylation K97 -0.546 _LK(gl)IPDHVR_
RB1 Phosphorylation T388 0.005 0.116 _TLQTDSIDSFETQRT(ph)PR_
RB1 Phosphorylation T405 -0.851 -0.901 _KSNLDEEVNVIPPHT(ph)PVR_
RB1 Phosphorylation S820 -0.019 _S(ph)PYKFPSSPLR_
RB1 Ubiquitylation K823 -2.214 _SPYK(gl)FPSSPLR_
RB1 Phosphorylation S827 0.824 0.111 _FPSS(ph)PLR_
RB1 Phosphorylation S839 -0.701 -1.045 _IPGGNIYIS(ph)PLKS(ph)PYK_
RB1 Ubiquitylation K842 -0.751 _IPGGNIYISPLK(gl)SPYK_
RB1 Phosphorylation S843 -0.701 -0.022 _IPGGNIYIS(ph)PLKS(ph)PYK_
RB1 Ubiquitylation K846 -2.084 _SPYK(gl)ISEGLPTPTK_
RB1 Phosphorylation T853 0.039 -0.555 _ISEGLPT(ph)PTKM(ox)T(ph)PR_
RB1 Ubiquitylation K856 -1.350 _ISEGLPTPTK(gl)MTPR_
RB1 Phosphorylation T858 -0.782 0.564 _ISEGLPT(ph)PTKMT(ph)PR_
RB1 Ubiquitylation K879 -0.187 _FQK(gl)INQMVCNSDR_
RHOB Ubiquitylation K135 0.050 -0.281 _MK(gl)QEPVRTDDGR_
RNF167 Ubiquitylation K156 0.487 _ALFVYEK(gl)GAR_
RNF167 Ubiquitylation K210 0.646 0.758 _LTK(gl)EQLK_
RNF167 Ubiquitylation K214 -0.449 -0.265 _EQLK(gl)QIPTHDYQK_
RNF167 Ubiquitylation K272 -0.086 0.259 _TCPICK(gl)QPVHR_
RUNX3 Ubiquitylation K244 0.258 _NASAVMK(gl)NQVAR_
TAF6 Ubiquitylation K357 0.692 0.215 _ITK(gl)TFTK_
TAF6 Phosphorylation S532 -1.108 -0.959 _AAAPPQPS(ph)PPPTK_
TAF6 Phosphorylation S653 -0.889 -1.013 _QEAGDS(ph)PPPAPGT(ph)PK_
TAF6 Phosphorylation T660 -0.889 -1.013 _QEAGDS(ph)PPPAPGT(ph)PK_
TGFB1 Ubiquitylation K50 -0.557 _GQILSK(gl)LR_
THAP5 Ubiquitylation K360 -0.457 _LK(gl)SLEALIR_
TP53BP2 Ubiquitylation K102 0.149 _SQDPSLK(gl)R_
TP53BP2 Ubiquitylation K152 0.224 _QQQQIEAQQQLLATK(gl)EQR_
TP53BP2 Ubiquitylation K224 -0.390 _LVEEIEQMNNLFQQK(gl)QR_
TP53BP2 Ubiquitylation K234 -0.113 _ELVLAVSK(gl)VEELTR_
TP53BP2 Ubiquitylation K268 -0.429 _LYK(gl)ELQLR_
TP53BP2 Ubiquitylation K283 -0.866 _NKLNQEQNAK(gl)LQQQR_
TP53BP2 Ubiquitylation K303 -0.302 _NSEVAVMDK(gl)R_
TP53BP2 Ubiquitylation K322 -2.045 _AALQQK(gl)ENLPVSSDGNLPQQAASAPSR_
TP53BP2 Phosphorylation S480 0.458 0.944 _NQS(ph)SEDILR_
TP53BP2 Phosphorylation S556 1.443 1.433 _VLLS(ph)PSIPSVGQDQTLSPGSK_
TP53BP2 Phosphorylation S569 1.774 _VLLS(ph)PSIPSVGQDQTLS(ph)PGSK_
TP53BP2 Phosphorylation S698 -0.309 -0.362 _IPRPLS(ph)PTK_
TP53BP2 Phosphorylation T700 -0.449 -0.429 _IPRPLSPT(ph)K_
TP53BP2 Phosphorylation S737 -0.172 -0.748 _RSS(ph)ITEPEGPNGPNIQK_
ZBTB17 Phosphorylation T119 -0.130 -0.375 _SLAEPAT(ph)SPGGNAEALATEGGDK_
ZBTB17 Phosphorylation S120 -0.091 -0.316 _SLAEPATS(ph)PGGNAEALATEGGDK_


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