bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: HTRA2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HTRA2 0 -0.874 1.220 -0.530 0.602 -0.023 1.287

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HTRA2 Ubiquitylation K237 -1.868 -0.270 _IQTK(gl)EPLPTLPLGR_

Background Information for HTRA2:


Pubmed-HTRA2 »
Uniprot-HTRA2 »
Biogrid-HTRA2 »
ProteomicsDB-HTRA2 »

Tumorportal-HTRA2 »
COSMIC-HTRA2 »
GenomeRNAi-HTRA2 »
Genecards-HTRA2


Protein-protein Interactions for HTRA2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BIRC2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BIRC7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BIRC8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPL4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RMND5A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDYHV1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in HTRA2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PDZ IPR001478 0.15
Category members Trypsin-like_Pept_dom IPR009003 0.04
Category members Peptidase_S1 IPR001254 0.01
Category members Peptidase_S1C IPR001940 0


Protein complexes (CORUM database) featuring HTRA2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5317 LATS1-HTRA2-BIRC4 complex Database 0


Categories featuring HTRA2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0051082 unfolded protein binding Database 3.74
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0045786 negative regulation of cell cycle Database 0.93
Category members GO Category GO:0010942 positive regulation of cell death Database 0.82
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0040014 regulation of multicellular organism growth Database 0.35
Category members GO Category GO:0005758 mitochondrial intermembrane space Database 0.33
Category members GO Category GO:0043065 positive regulation of apoptotic process Database 0.26
Category members GO Category GO:0034605 cellular response to heat Database 0.18
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members GO Category GO:0004252 serine-type endopeptidase activity Database 0.05
Category members GO Category GO:0008233 peptidase activity Database 0.02
Category members Pathway Pathway_31 KEGG_PARKINSONS_DISEASE 0 0
Category members Disease phenotype PARKINSON_DISEASE_LATE-ONSET PARKINSON DISEASE LATE-ONSET Database 0
Category members Disease phenotype Young_adult-onset_Parkinsonism Young adult-onset Parkinsonism Database 0
Category members GO Category GO:0006508 proteolysis Database 0
Category members GO Category GO:0006672 ceramide metabolic process Database 0
Category members GO Category GO:0007005 mitochondrion organization Database 0
Category members GO Category GO:0007628 adult walking behavior Database 0
Category members GO Category GO:0008236 serine-type peptidase activity Database 0
Category members GO Category GO:0008344 adult locomotory behavior Database 0
Category members GO Category GO:0009635 response to herbicide Database 0
Category members GO Category GO:0009898 cytoplasmic side of plasma membrane Database 0
Category members GO Category GO:0030900 forebrain development Database 0
Category members GO Category GO:0031966 mitochondrial membrane Database 0
Category members GO Category GO:0035631 CD40 receptor complex Database 0
Category members GO Category GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process Database 0
Category members GO Category GO:0048666 neuron development Database 0
Category members GO Category GO:0060548 negative regulation of cell death Database 0
Category members GO Category GO:0071363 cellular response to growth factor stimulus Database 0


.

© Copyright Svejstrup Laboratory 2015