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Results for the Category
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
(GO:0043280)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
HMGB1 2 -1.590 3.400 2.856 -1.899 0.030 -0.792
DDX3X 2 -0.250 0.370 0.081 -0.794 -0.166 -0.062 -0.025
MAPK9 1 0.110 -0.490
BCL10 1 0.000 0.200
BAD 0 -0.660 1.190
RHOA 0 -0.510 1.370 -0.485 0.532 0.279
REST 0 -0.120 -0.050 -0.002 -1.235 -0.636
SIRT1 0 0.910 -0.910
HTRA2 0 1.220 -0.530 0.602 -0.023 1.287
MEN1 0 1.080 -1.150 0.101 0.684 -0.063
MEN1 0 1.080 -1.150 0.395
MEN1 0 1.080 -1.150
MYC 0 0.170 0.550 -2.443 -0.949 -0.454 -1.290
UACA 0 -0.200 -0.170 0.298 0.359
PMAIP1 0 0.570 -0.670
PINX1 0 -0.245 0.016
SOX7 0 0.510 -0.520 -0.245 0.016
F2R 0 0.220 0.110
MAP3K5 0 0.710 -0.770
FIS1 0 0.310 -0.460 -0.182 -0.304

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
BAD Phosphorylation S74 -0.904 -0.452 _HS(ph)SYPAGTEDDEGM(ox)GEEPSPFR_
BAD Phosphorylation S75 -0.914 -0.660 _HSS(ph)YPAGTEDDEGMGEEPSPFR_
BAD Phosphorylation S97 0.056 _S(ph)RSAPPNLWAAQR_
BAD Phosphorylation S99 -0.299 0.161 _S(ph)APPNLWAAQR_
BAD Phosphorylation S118 1.277 1.089 _RM(ox)S(ph)DEFVDSFKK_
BCL10 Phosphorylation S138 1.515 1.393 _SNS(ph)DESNFSEK_
DDX3X Ubiquitylation K78 1.311 _DK(gl)DAYSSFGSR_
DDX3X Ubiquitylation K93 0.657 1.846 _GK(gl)SSFFSDR_
DDX3X Phosphorylation S94 0.172 _S(ph)SFFSDRGSGSR_
DDX3X Phosphorylation S102 0.008 0.230 _SSFFSDRGS(ph)GSR_
DDX3X Phosphorylation S104 -0.231 0.320 _SSFFSDRGSGS(ph)R_
DDX3X Ubiquitylation K130 1.572 1.502 _SGFGK(gl)FER_
DDX3X Ubiquitylation K347 -0.406 0.360 _GK(gl)IGLDFCK_
DDX3X Ubiquitylation K503 -0.796 _SGK(gl)SPILVATAVAAR_
DDX3X Phosphorylation S602 -0.349 _S(ph)SRFSGGFGAR_
DDX3X Phosphorylation S603 -0.330 _SS(ph)RFSGGFGAR_
DDX3X Phosphorylation S606 -0.248 -0.447 _FS(ph)GGFGAR_
F2R Ubiquitylation K421 0.836 0.568 _MDTCSSNLNNSIYK(gl)K_
FIS1 Ubiquitylation K25 0.414 0.808 _FQSEK(gl)AAGSVSK_
FIS1 Ubiquitylation K46 0.800 0.340 _SK(gl)YNDDIRK_
FIS1 Ubiquitylation K108 -0.706 _GLLQTEPQNNQAK(gl)ELER_
HMGB1 Ubiquitylation K50 0.651 _WK(gl)TMSAK_
HMGB1 Ubiquitylation K59 1.001 0.009 _GK(gl)FEDMAK_
HMGB1 Ubiquitylation K114 0.314 _IK(gl)GEHPGLSIGDVAK_
HMGB1 Ubiquitylation K127 0.018 _IKGEHPGLSIGDVAK(gl)K_
HMGB1 Ubiquitylation K128 -0.407 _K(gl)LGEMWNNTAADDKQPYEK_
HMGB1 Ubiquitylation K157 0.850 _YEK(gl)DIAAYR_
HTRA2 Ubiquitylation K237 -1.868 -0.270 _IQTK(gl)EPLPTLPLGR_
MAP3K5 Phosphorylation S1066 -1.241 _SISLPVPVLVEDTSSSSEYGSVS(ph)PDTELKVDPFSFK_
MAP3K5 Phosphorylation S1113 -1.408 -0.562 _TLFLGIPDENFEDHSAPPS(ph)PEEK_
MAPK9 Phosphorylation Y185 3.533 _TACTNFMMTPY(ph)VVTR_
MEN1 Ubiquitylation K8 -1.132 0.088 _AAQK(gl)TLFPLR_
MEN1 Phosphorylation S218 -0.820 _RES(ph)KPEEPPPPK_
MYC Phosphorylation S20 -1.444 -1.145 _PLNVS(ph)FTNR_
MYC Phosphorylation T72 -1.699 -1.813 _FELLPT(ph)PPLS(ph)PSRR_
MYC Phosphorylation S76 -1.777 -1.435 _FELLPTPPLS(ph)PSR_
MYC Phosphorylation S81 0.459 _S(ph)GLCSPSYVAVTPFSLR_
MYC Phosphorylation S85 0.199 0.073 _SGLCS(ph)PSYVAVTPFSLR_
MYC Ubiquitylation K162 -2.475 -1.259 _LVSEK(gl)LASYQAAR_
MYC Phosphorylation S295 -0.903 _SESGS(ph)PSAGGHSKPPHSPLVLK_
MYC Phosphorylation S307 -1.486 _SES(ph)GSPSAGGHSKPPHS(ph)PLVLK_
MYC Ubiquitylation K340 -2.449 _VK(gl)LDSVR_
MYC Ubiquitylation K403 -3.432 _DQIPELENNEK(gl)APK_
PMAIP1 Ubiquitylation K35 -1.475 0.286 _RFGDK(gl)LNFR_
PMAIP1 Ubiquitylation K41 -1.597 0.340 _QK(gl)LLNLISK_
PMAIP1 Ubiquitylation K48 -2.007 -0.586 _LLNLISK(gl)_
REST Ubiquitylation K280 0.406 _VYTCGK(gl)CNYFSDR_
REST Phosphorylation S864 -3.456 _ESVSTEDLSPPS(ph)PPLPK_
RHOA Ubiquitylation K6 0.708 _K(gl)KLVIVGDGACGK_
RHOA Ubiquitylation K7 0.708 _K(gl)KLVIVGDGACGK_
RHOA Ubiquitylation K118 -0.408 _HFCPNVPIILVGNK(gl)K_
RHOA Ubiquitylation K119 -0.408 _HFCPNVPIILVGNK(gl)K_
RHOA Ubiquitylation K135 -0.528 -0.796 _MK(gl)QEPVKPEEGRDMANR_
RHOA Ubiquitylation K162 0.345 0.453 _IGAFGYMECSAK(gl)TK_
SIRT1 Phosphorylation S14 -0.369 -0.246 _(ac)ADEAALALQPGGS(ph)PSAAGADR_
SIRT1 Phosphorylation S16 -0.306 -1.665 _(ac)ADEAALALQPGGS(ph)PS(ph)AAGADREAASSPAGEPLR_
SIRT1 Phosphorylation S26 -1.047 -0.245 _EAAS(ph)SPAGEPLR_
SIRT1 Phosphorylation S27 0.351 -0.363 _EAASS(ph)PAGEPLR_
SIRT1 Phosphorylation S47 -0.574 -0.607 _S(ph)PGEPGGAAPER_
SIRT1 Ubiquitylation K238 -1.641 _RK(gl)DINTIEDAVK_
SIRT1 Ubiquitylation K499 -2.138 -0.204 _LGGEYAK(gl)LCCNPVK_
SIRT1 Ubiquitylation K578 -2.782 _GCMEEK(gl)PQEVQTSR_
SIRT1 Ubiquitylation K601 -3.051 _NVESIAEQMENPDLK(gl)NVGSSTGEK_


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