bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: F2R

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
F2R 0 1.405 0.220 0.110

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
F2R Ubiquitylation K421 0.836 0.568 _MDTCSSNLNNSIYK(gl)K_

Background Information for F2R:


Pubmed-F2R »
Uniprot-F2R »
Biogrid-F2R »
ProteomicsDB-F2R »

Tumorportal-F2R »
COSMIC-F2R »
GenomeRNAi-F2R »
Genecards-F2R


Protein-protein Interactions for F2R
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CRYL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GRPR Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in F2R
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members GPCR_Rhodpsn IPR000276 2.56
Category members GPCR_Rhodpsn_7TM IPR017452 2.32
Category members Protea_act_rcpt IPR003912 0


Protein complexes (CORUM database) featuring F2R
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring F2R
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005576 extracellular region Database 10.9
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members Pathway Pathway_1105 REACTOME_GPCR_LIGAND_BINDING 0 2.35
Category members GO Category GO:0004930 G-protein coupled receptor activity Database 2.1
Category members Pathway Pathway_1184 KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION 0 1.89
Category members Pathway Pathway_1182 REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS 0 1.69
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members GO Category GO:0007186 G-protein coupled receptor signaling pathway Database 1.53
Category members Pathway Pathway_243 REACTOME_GPCR_DOWNSTREAM_SIGNALING 0 1.27
Category members Pathway Pathway_666 KEGG_ENDOCYTOSIS 0 1.25
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_240 BIOCARTA_PAR1_PATHWAY 0 1.11
Category members Pathway Pathway_256 REACTOME_SIGNALING_BY_GPCR 0 0.83
Category members GO Category GO:0043524 negative regulation of neuron apoptotic process Database 0.66
Category members GO Category GO:0070374 positive regulation of ERK1 and ERK2 cascade Database 0.65
Category members Pathway Pathway_1186 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS 0 0.54
Category members GO Category GO:0006954 inflammatory response Database 0.49
Category members Pathway Pathway_53 REACTOME_HEMOSTASIS 0 0.4
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members GO Category GO:0046427 positive regulation of JAK-STAT cascade Database 0.39
Category members GO Category GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway Database 0.36
Category members GO Category GO:0032496 response to lipopolysaccharide Database 0.35
Category members GO Category GO:0030193 regulation of blood coagulation Database 0.29
Category members GO Category GO:0008285 negative regulation of cell proliferation Database 0.28
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members Pathway Pathway_428 PID_THROMBIN_PAR1_PATHWAY 0 0.18
Category members GO Category GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway Database 0.18
Category members GO Category GO:0015057 thrombin receptor activity Database 0.17
Category members GO Category GO:0000186 activation of MAPKK activity Database 0.16
Category members GO Category GO:0030168 platelet activation Database 0.13
Category members Pathway Pathway_233 KEGG_CALCIUM_SIGNALING_PATHWAY 0 0.13
Category members GO Category GO:0060155 platelet dense granule organization Database 0.11
Category members Pathway Pathway_56 REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION 0 0.11
Category members Pathway Pathway_580 KEGG_REGULATION_OF_ACTIN_CYTOSKELETON 0 0.08
Category members GO Category GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process Database 0.08
Category members GO Category GO:0031094 platelet dense tubular network Database 0.07
Category members GO Category GO:0043410 positive regulation of MAPK cascade Database 0.06
Category members GO Category GO:0045211 postsynaptic membrane Database 0.06
Category members Pathway Pathway_680 BIOCARTA_SPPA_PATHWAY 0 0.05
Category members GO Category GO:0007260 tyrosine phosphorylation of STAT protein Database 0.04
Category members GO Category GO:0031681 G-protein beta-subunit binding Database 0.04
Category members Pathway Pathway_486 REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS 0 0.04
Category members GO Category GO:0048873 homeostasis of number of cells within a tissue Database 0.04
Category members GO Category GO:0051209 release of sequestered calcium ion into cytosol Database 0.01
Category members Pathway Pathway_1189 KEGG_COMPLEMENT_AND_COAGULATION_CASCADES 0 0
Category members Pathway Pathway_1194 BIOCARTA_AMI_PATHWAY 0 0
Category members Pathway Pathway_1195 BIOCARTA_EXTRINSIC_PATHWAY 0 0
Category members Pathway Pathway_1196 BIOCARTA_INTRINSIC_PATHWAY 0 0
Category members Pathway Pathway_1197 BIOCARTA_FIBRINOLYSIS_PATHWAY 0 0
Category members Pathway Pathway_487 REACTOME_GASTRIN_CREB_SIGNALLING_PATHWAY_VIA_PKC_AND_MAPK 0 0
Category members Pathway Pathway_994 REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS 0 0
Category members GO Category GO:0001965 G-protein alpha-subunit binding Database 0
Category members GO Category GO:0002248 connective tissue replacement involved in inflammatory response wound healing Database 0
Category members GO Category GO:0003105 negative regulation of glomerular filtration Database 0
Category members GO Category GO:0005102 receptor binding Database 0
Category members GO Category GO:0005901 caveola Database 0
Category members GO Category GO:0007204 positive regulation of cytosolic calcium ion concentration Database 0
Category members GO Category GO:0007262 STAT protein import into nucleus Database 0
Category members GO Category GO:0007529 establishment of synaptic specificity at neuromuscular junction Database 0
Category members GO Category GO:0008284 positive regulation of cell proliferation Database 0
Category members GO Category GO:0009611 response to wounding Database 0
Category members GO Category GO:0009653 anatomical structure morphogenesis Database 0
Category members GO Category GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling Database 0
Category members GO Category GO:0016265 death Database 0
Category members GO Category GO:0030194 positive regulation of blood coagulation Database 0
Category members GO Category GO:0030335 positive regulation of cell migration Database 0
Category members GO Category GO:0031594 neuromuscular junction Database 0
Category members GO Category GO:0032651 regulation of interleukin-1 beta production Database 0
Category members GO Category GO:0032967 positive regulation of collagen biosynthetic process Database 0
Category members GO Category GO:0035025 positive regulation of Rho protein signal transduction Database 0
Category members GO Category GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling Database 0
Category members GO Category GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process Database 0
Category members GO Category GO:0045907 positive regulation of vasoconstriction Database 0
Category members GO Category GO:0045987 positive regulation of smooth muscle contraction Database 0
Category members GO Category GO:0051281 positive regulation of release of sequestered calcium ion into cytosol Database 0
Category members GO Category GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway Database 0
Category members GO Category GO:0051928 positive regulation of calcium ion transport Database 0
Category members GO Category GO:0051930 regulation of sensory perception of pain Database 0
Category members GO Category GO:0070493 thrombin receptor signaling pathway Database 0


.

© Copyright Svejstrup Laboratory 2015