Results for the Category
positive regulation of phosphatidylinositol 3-kinase signaling
(GO:0014068)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| UBE3A | 2 | -0.310 | -0.470 | |||||
| CAT | 2 | 2.260 | -1.180 | 1.895 | -0.238 | |||
| PDGFA | 1 | 0.190 | -0.340 | -2.109 | 1.885 | |||
| NEDD4 | 0 | -1.320 | 1.730 | |||||
| FGFR1 | 0 | 0.210 | 0.150 | |||||
| FLT1 | 0 | -1.240 | 1.900 | |||||
| UNC5B | 0 | 0.370 | -0.700 | |||||
| KDR | 0 | 0.860 | -0.680 | |||||
| HAX1 | 0 | 0.350 | -0.770 | -0.053 | -0.086 | -0.378 | ||
| F2RL1 | 0 | -1.330 | 2.490 | |||||
| F2R | 0 | 0.220 | 0.110 | |||||
| PRR5 | 0 | |||||||
| SEMA4D | 0 | -0.540 | 0.790 | |||||
| SEMA4D | 0 | 0.260 | -0.350 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| F2R | Ubiquitylation | K421 | 0.836 | 0.568 | _MDTCSSNLNNSIYK(gl)K_ |
| F2RL1 | Ubiquitylation | K368 | 0.159 | 0.737 | _TVK(gl)QMQVSLTSK_ |
| F2RL1 | Ubiquitylation | K377 | -0.040 | -0.268 | _QMQVSLTSK(gl)K_ |
| F2RL1 | Ubiquitylation | K378 | 0.066 | -0.268 | _QMQVSLTSKK(gl)_ |
| F2RL1 | Phosphorylation | S384 | 0.573 | 1.068 | _KSS(ph)SYSSSSTTVK_ |
| F2RL1 | Ubiquitylation | K394 | 0.350 | 0.873 | _KSSSYSSSSTTVK(gl)TSY_ |
| FGFR1 | Ubiquitylation | K510 | 1.047 | -0.221 | _VTK(gl)VAVK_ |
| FLT1 | Ubiquitylation | K953 | -1.081 | _MEPGLEQGK(gl)KPR_ | |
| HAX1 | Ubiquitylation | K131 | -1.235 | -0.518 | _DSMLK(gl)YPDSHQPR_ |
| HAX1 | Ubiquitylation | K209 | -0.627 | 0.782 | _SYFK(gl)SISVTK_ |
| KDR | Ubiquitylation | K1064 | -1.119 | _DIYK(gl)DPDYVR_ | |
| NEDD4 | Phosphorylation | Y751 | -0.924 | _RGSLQAY(ph)TFEEQPTLPVLLPTSSGLPPGWEEK_ | |
| NEDD4 | Ubiquitylation | K874 | 0.127 | _LK(gl)IPAHLR_ | |
| NEDD4 | Ubiquitylation | K882 | -0.919 | 0.114 | _GK(gl)TSLDTSNDLGPLPPGWEER_ |
| PRR5 | Phosphorylation | S34 | -0.311 | 0.097 | _FM(ox)S(ph)SPSLSDLGK_ |
| PRR5 | Phosphorylation | S332 | -0.958 | -0.916 | _S(ph)SPAPHSGPCPSR_ |
| PRR5 | Phosphorylation | S333 | -0.958 | -0.916 | _S(ph)SPAPHSGPCPSR_ |
| SEMA4D | Ubiquitylation | K784 | 0.913 | 1.205 | _SALLIGKK(gl)_ |
| SEMA4D | Ubiquitylation | K857 | 0.832 | _DKPFDVK(gl)CELK_ | |
| UBE3A | Ubiquitylation | K77 | 0.131 | 0.538 | _ALELYK(gl)INAK_ |
| UBE3A | Ubiquitylation | K89 | -0.782 | _LCDPHPSK(gl)K_ | |
| UBE3A | Ubiquitylation | K90 | -0.804 | _LCDPHPSKK(gl)_ | |
| UBE3A | Ubiquitylation | K112 | -0.670 | _GAPNNSCSEIK(gl)MNKK_ | |
| UBE3A | Ubiquitylation | K123 | 0.184 | _IDFK(gl)DVTYLTEEK_ | |
| UBE3A | Phosphorylation | S218 | 3.592 | 3.254 | _IGDSS(ph)QGDNNLQK_ |
| UBE3A | Ubiquitylation | K315 | -0.507 | _AMSK(gl)LPLAAQGK_ | |
| UBE3A | Ubiquitylation | K323 | -0.547 | _LPLAAQGK(gl)LIR_ | |
| UBE3A | Ubiquitylation | K373 | 1.085 | 1.052 | _NLVNDDDAIVAASK(gl)CLK_ |
| UBE3A | Ubiquitylation | K552 | -0.235 | 0.125 | _LEMIAMENPADLK(gl)K_ |
| UBE3A | Ubiquitylation | K553 | -0.235 | 0.125 | _LEMIAMENPADLK(gl)K_ |
| UBE3A | Ubiquitylation | K824 | 0.226 | _LK(gl)MIIAK_ | |
| UNC5B | Phosphorylation | S528 | -0.838 | _SAS(ph)LGSQQLLGLPR_ |
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