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Query: UNC5B

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
UNC5B 0 -0.838 0.370 -0.700

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
UNC5B Phosphorylation S528 -0.838 _SAS(ph)LGSQQLLGLPR_

Background Information for UNC5B:


Pubmed-UNC5B »
Uniprot-UNC5B »
Biogrid-UNC5B »
ProteomicsDB-UNC5B »

Tumorportal-UNC5B »
COSMIC-UNC5B »
GenomeRNAi-UNC5B »
Genecards-UNC5B


Protein-protein Interactions for UNC5B
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait LRRIQ1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in UNC5B
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members DEATH-like_dom IPR011029 1.15
Category members Ig-like_dom IPR007110 0.6
Category members Ig_sub IPR003599 0.43
Category members Ig_sub2 IPR003598 0.21
Category members Ig_I-set IPR013098 0.13
Category members Death_domain IPR000488 0.08
Category members Thrombospondin_1_rpt IPR000884 0.01
Category members ZU5_dom IPR000906 0


Protein complexes (CORUM database) featuring UNC5B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring UNC5B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members Pathway Pathway_837 REACTOME_APOPTOSIS 0 2.39
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members Pathway Pathway_673 REACTOME_AXON_GUIDANCE 0 1.06
Category members Pathway Pathway_1016 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS 0 0.87
Category members GO Category GO:0042981 regulation of apoptotic process Database 0.79
Category members GO Category GO:0043524 negative regulation of neuron apoptotic process Database 0.66
Category members Pathway Pathway_42 REACTOME_DEVELOPMENTAL_BIOLOGY 0 0.32
Category members Pathway Pathway_795 REACTOME_REGULATION_OF_APOPTOSIS 0 0.31
Category members GO Category GO:0043065 positive regulation of apoptotic process Database 0.26
Category members GO Category GO:0033564 anterior/posterior axon guidance Database 0.2
Category members GO Category GO:0007411 axon guidance Database 0.13
Category members Pathway Pathway_1034 KEGG_AXON_GUIDANCE 0 0.04
Category members Pathway Pathway_640 PID_NETRIN_PATHWAY 0 0
Category members Pathway Pathway_692 REACTOME_NETRIN1_SIGNALING 0 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling Database 0


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