RNAi screen result	RNAPII IP (MG132)	CSB IP	CSB IP (MG132)	Chrom.	Chrom. (MG132)	Ubi /Phospo	Ubi /Phospho (MG132)
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Gene name	MGoogle Score	RNAi high	RNAi low	RNAPII-IP (MG132)	CSB-IP	CSB-IP (MG132)	Chrom.	Chrom. (MG132)
ITPR3	2	-0.190	-0.500				1.489	1.835
DGKD	1	-1.930	3.220
GNA11	1	2.030	-1.240	0.953			0.764	0.108
PIK3R2	1	2.740	-1.180				0.269	0.348
RAF1	1	2.020	-1.230
KRAS	1	-0.510	0.620				1.031	0.887
KRAS	1	-0.510	0.620				0.246	-0.346
ANXA1	1	1.050	-0.850				1.883
MAP2K1	1	-1.590	2.780
RPS6KA3	1	-1.550	2.890
NRAS	1	1.810	-0.720				0.246	-0.346
PRKCH	0	1.450	-1.320
TRIO	0	-0.690	0.810				0.256	0.123
UTS2	0	-0.560	0.180		-0.048	0.360
PRKCQ	0	0.410	0.020
GNB1	0	-0.700	0.650	0.713			0.504	0.538
GNB3	0	-1.020	1.280	0.713			0.504	0.538
PLCB4	0	0.640	-0.400
DGKH	0	-1.220	0.820
MAPK3	0
GNB4	0	0.410	-0.240	0.137			0.627	1.296
GNB4	0	0.410	-0.240
SOS1	0	0.500	-0.620	-0.570
PIK3R3	0	-0.140	-0.480
PIK3R3	0	-0.140	-0.480				-0.441	0.147
RPS6KA1	0	-0.160	-0.660
RPS6KA1	0	-0.160	-0.660
CREB1	0	1.080	-0.800			-1.027
PIK3CA	0
ITPR2	0	-1.020	0.610				0.952	0.981
MAP2K2	0	-0.610	0.080
MAP2K2	0	-0.610	0.080
APP	0	0.100	-0.260					0.285
PIK3R1	0	1.910	-1.220				-0.441	0.147
EGFR	0	-0.580	0.520				0.513	0.090
DGKE	0	-0.800	1.500				-0.239	0.518
PRKCA	0	0.750	-0.690				0.349	0.585
PRKCA	0	0.750	-0.690
GNA14	0	1.610	-0.450					0.492
GNAQ	0	0.140	-0.310				0.052	0.449
PRKCD	0	0.250	0.070				0.578	0.427
F2RL1	0	-1.330	2.490
YWHAB	0				0.628	-0.543
YWHAB	0			0.507			0.271	0.503
GNG4	0	0.310	-0.680
CDK1	0	-0.370	0.080	-0.202	-0.884	-0.107	-0.097	-0.501
GNB2	0	0.120	-0.090	0.137			0.627	1.296
GNG12	0	1.160	-1.150				-1.317
GNG12	0	1.160	-1.150
ADRBK1	0	-0.390	0.360
ADRBK1	0	-0.340	0.480
GNG5	0	-0.100	-0.480
HRAS	0	1.470	-0.520
GRB2	0	-0.240	0.300		-1.021	0.057	0.906
F2R	0	0.220	0.110
PLCB1	0	-0.300	-0.220

Gene name	PTM type	PTM site	UV	UV (MG132)	Sequence
ADRBK1	Phosphorylation	S670	1.038	0.924	_NKPRS(ph)PVVELSK_
ADRBK1	Phosphorylation	S676		1.113	_NKPRSPVVELS(ph)K_
APP	Ubiquitylation	K751	-1.778	-1.280	_HLSK(gl)M(ox)QQNGYENPTYK_
CDK1	Ubiquitylation	K6	0.011	-0.784	_(ac)M(ox)EDYTK(gl)IEK_
CDK1	Ubiquitylation	K20	-0.327	-0.270	_IGEGTYGVVYK(gl)GR_
CDK1	Ubiquitylation	K33	0.736	0.239	_TTGQVVAMK(gl)K_
CDK1	Ubiquitylation	K34		-0.306	_TTGQVVAMKK(gl)_
CDK1	Ubiquitylation	K58	0.312	-0.262	_EISLLK(gl)ELR_
CDK1	Ubiquitylation	K136		-0.468	_DLK(gl)PQNLLIDDK(gl)GTIK_
CDK1	Ubiquitylation	K145	0.161	-0.954	_DLKPQNLLIDDK(gl)GTIK_
CDK1	Ubiquitylation	K149		-0.038	_GTIK(gl)LADFGLAR_
CDK1	Ubiquitylation	K251	-0.047	-1.236	_WK(gl)PGSLASHVK_
CDK1	Ubiquitylation	K280	0.179	-1.210	_MLIYDPAK(gl)R_
CREB1	Phosphorylation	S271	-0.979	-1.450	_TAPTSTIAPGVVM(ox)ASS(ph)PALPTQPAEEAAR_
CREB1	Ubiquitylation	K333	1.343		_ALK(gl)DLYCHK_
DGKD	Phosphorylation	S56	0.319	0.732	_KVS(ph)TSGQIR_
DGKE	Ubiquitylation	K212		-0.965	_TDYEVLASK(gl)LGK_
DGKE	Ubiquitylation	K357	-0.396	0.179	_VQVTNK(gl)GYYNLR_
DGKH	Phosphorylation	S56	0.319	0.732	_KVS(ph)TSGQIR_
EGFR	Phosphorylation	T693	0.486	-0.139	_ELVEPLT(ph)PSGEAPNQALLR_
EGFR	Phosphorylation	S991		-0.041	_MHLPS(ph)PTDSNFYR_
F2R	Ubiquitylation	K421	0.836	0.568	_MDTCSSNLNNSIYK(gl)K_
F2RL1	Ubiquitylation	K368	0.159	0.737	_TVK(gl)QMQVSLTSK_
F2RL1	Ubiquitylation	K377	-0.040	-0.268	_QMQVSLTSK(gl)K_
F2RL1	Ubiquitylation	K378	0.066	-0.268	_QMQVSLTSKK(gl)_
F2RL1	Phosphorylation	S384	0.573	1.068	_KSS(ph)SYSSSSTTVK_
F2RL1	Ubiquitylation	K394	0.350	0.873	_KSSSYSSSSTTVK(gl)TSY_
GNA11	Ubiquitylation	K16	0.347		_(ac)TLESMMACCLSDEVK(gl)ESKR_
GNA11	Ubiquitylation	K27	0.292	1.135	_RINAEIEK(gl)QLR_
GNA11	Ubiquitylation	K102	0.502	0.512	_ILYK(gl)YEQNK_
GNAQ	Ubiquitylation	K16	0.245		_TLESIMACCLSEEAK(gl)EAR_
GNAQ	Ubiquitylation	K102	-0.299		_IPYK(gl)YEHNK_
GNB1	Ubiquitylation	K23	-0.282		_K(gl)ACADATLSQITNNIDPVGR_
GNB1	Ubiquitylation	K209	-0.296	-0.249	_LFVSGACDASAK(gl)LWDVR_
GNB2	Ubiquitylation	K23	-0.095	0.033	_K(gl)ACGDSTLTQITAGLDPVGR_
GNB2	Ubiquitylation	K209	0.251	0.419	_TFVSGACDASIK(gl)LWDVR_
GNB3	Ubiquitylation	K23	-0.282		_K(gl)ACADATLSQITNNIDPVGR_
GNB3	Ubiquitylation	K209	-0.296	-0.249	_LFVSGACDASAK(gl)LWDVR_
GNB4	Ubiquitylation	K23	-0.095	0.033	_K(gl)ACGDSTLTQITAGLDPVGR_
GNB4	Ubiquitylation	K23	-0.030		_K(gl)ACNDATLVQITSNMDSVGR_
GNB4	Ubiquitylation	K209	0.251	0.419	_TFVSGACDASIK(gl)LWDVR_
GNB4	Ubiquitylation	K209		0.019	_TFVSGACDASSK(gl)LWDIR_
GNG12	Ubiquitylation	K4	0.230	0.493	_(ac)SSK(gl)TASTNNIAQAR_
GNG12	Ubiquitylation	K34	0.515	1.067	_VSK(gl)ASADLMSYCEEHAR_
GNG4	Ubiquitylation	K24	1.031	0.205	_KAVEQLK(gl)MEACMDR_
GNG5	Ubiquitylation	K11	-0.523	0.125	_(ac)SGSSSVAAMK(gl)K_
GNG5	Ubiquitylation	K12	0.232	0.466	_K(gl)VVQQLR_
GNG5	Ubiquitylation	K27	-0.760	0.148	_VK(gl)VSQAAADLK_
GRB2	Ubiquitylation	K10	0.146		_YDFK(gl)ATADDELSFK_
GRB2	Ubiquitylation	K20	-0.078		_ATADDELSFK(gl)R_
GRB2	Ubiquitylation	K69	-0.362	0.641	_AK(gl)AEEMLSK_
GRB2	Ubiquitylation	K76	0.754		_AEEMLSK(gl)QR_
GRB2	Ubiquitylation	K109	0.381	-0.002	_FGNDVQHFK(gl)VLR_
HRAS	Ubiquitylation	K170	-1.005		_K(gl)LNPPDESGPGCMSCK_
ITPR2	Ubiquitylation	K909		-0.247	_LSK(gl)FQDGGNNVMR_
ITPR2	Phosphorylation	S1160	0.443	0.895	_GGEEPIEESNILS(ph)PVQDGTK_
ITPR3	Ubiquitylation	K529	1.377		_EK(gl)GGEGPLVR_
ITPR3	Phosphorylation	S934	0.318	-0.802	_KQS(ph)VFSAPSLSAGASAAEPLDR_
ITPR3	Phosphorylation	S937		-0.026	_KQSVFS(ph)APSLSAGASAAEPLDR_
ITPR3	Ubiquitylation	K1534		-0.220	_TLAMVAK(gl)GR_
ITPR3	Phosphorylation	S1832	0.650	0.560	_VAS(ph)FSIPGSSSR_
ITPR3	Ubiquitylation	K2597		-0.819	_NK(gl)NLDWFPR_
ITPR3	Ubiquitylation	K2628		-0.010	_ILQDK(gl)LNSTMK_
ITPR3	Phosphorylation	S2670	1.132	1.555	_LGFVDVQNCIS(ph)R_
KRAS	Ubiquitylation	K128	1.528	1.433	_TVDTK(gl)QAHELAK_
KRAS	Ubiquitylation	K235	0.591	0.087	_TVDTK(gl)QAQDLAR_
KRAS	Ubiquitylation	K254	-0.450	-0.156	_SYGIPFIETSAK(gl)TR_
MAP2K1	Ubiquitylation	K192	-0.205	-0.241	_DVK(gl)PSNILVNSR_
MAP2K1	Phosphorylation	S385		0.066	_RSDAEEVDFAGWLCSTIGLNQPS(ph)TPTHAAGV_
MAP2K1	Phosphorylation	T386		0.377	_RSDAEEVDFAGWLCSTIGLNQPST(ph)PTHAAGV_
MAP2K2	Phosphorylation	S23	0.873	0.258	_RKPVLPALTINPTIAEGPS(ph)PTSEGASEANLVDLQK_
MAP2K2	Phosphorylation	T25		0.439	_RKPVLPALTINPTIAEGPSPT(ph)SEGASEANLVDLQK_
MAP2K2	Ubiquitylation	K192	-0.205	-0.241	_DVK(gl)PSNILVNSR_
MAP2K2	Phosphorylation	S293		-0.361	_ELEAIFGRPVVDGEEGEPHS(ph)ISPR_
MAP2K2	Phosphorylation	S295	-0.234	0.026	_ELEAIFGRPVVDGEEGEPHSIS(ph)PR_
MAP2K2	Phosphorylation	T394	0.570	0.158	_LNQPGT(ph)PTR_
MAPK3	Phosphorylation	Y204	-0.807	-2.487	_IADPEHDHTGFLTEY(ph)VATR_
MAPK3	Ubiquitylation	K289		-0.608	_NYLQSLPSKTK(gl)_
NRAS	Ubiquitylation	K128	1.528	1.433	_TVDTK(gl)QAHELAK_
PIK3CA	Ubiquitylation	K864	0.390	0.588	_NSHTIM(ox)QIQCK(gl)GGLK_
PIK3CA	Ubiquitylation	K868	0.204	0.651	_NSHTIM(ox)QIQCKGGLK(gl)_
PIK3CA	Ubiquitylation	K974	-0.273		_GAQECTK(gl)TREFER_
PIK3R2	Phosphorylation	S262		-2.237	_APPPPS(ph)SPPPGGAPDGSEPSPDFPALLVEK_
PIK3R2	Phosphorylation	S263		-2.237	_APPPPS(ph)SPPPGGAPDGSEPSPDFPALLVEK_
PIK3R2	Ubiquitylation	K500	-0.189		_IFEEQGQTQEK(gl)CSK_
PIK3R2	Ubiquitylation	K541	-0.609		_TK(gl)LEQQLR_
PIK3R2	Ubiquitylation	K564	-0.431	-1.022	_MNSLK(gl)PDLMQLR_
PIK3R3	Ubiquitylation	K226		-0.376	_YQQDQLVKEDNIDAVGKK(gl)_
PIK3R3	Ubiquitylation	K320		0.385	_LGEIHDSK(gl)MR_
PLCB1	Phosphorylation	S1199	-0.494		_TPS(ph)SEELGGDIPGKEFDTPL_
PLCB1	Phosphorylation	S1200		-0.483	_TPSS(ph)EELGGDIPGKEFDTPL_
PLCB4	Ubiquitylation	K284	1.083	0.038	_K(gl)GLISSDGFCR_
PRKCA	Phosphorylation	S10	-0.650	0.036	_(ac)ADVFPGNDS(ph)TASQDVANR_
PRKCA	Phosphorylation	S13	-1.038	0.335	_(ac)ADVFPGNDSTAS(ph)QDVANR_
PRKCA	Phosphorylation	S226	0.693	0.415	_STLNPQWNES(ph)FTFK_
PRKCA	Ubiquitylation	K316	-0.522	-0.535	_LGPAGNK(gl)VISPSEDR_
PRKCD	Ubiquitylation	K138	-0.141		_SEDEAK(gl)FPTMNR_
PRKCD	Ubiquitylation	K222	0.185	0.658	_DTIFQK(gl)ER_
PRKCD	Phosphorylation	S302	-0.240	-0.222	_S(ph)DSASSEPVGIYQGFEK_
PRKCD	Phosphorylation	S304	0.378	0.289	_RSDS(ph)ASSEPVGIYQGFEK_
PRKCD	Phosphorylation	S506	-0.213	0.200	_AS(ph)TFCGTPDYIAPEILQGLK_
PRKCD	Phosphorylation	T507	-0.149	0.240	_AS(ph)TFCGTPDYIAPEILQGLK_
PRKCD	Ubiquitylation	K641	-2.000		_DYSNFDQEFLNEK(gl)AR_
PRKCD	Phosphorylation	S645	0.577	0.832	_ARLS(ph)YSDK_
PRKCD	Phosphorylation	S647	0.886	0.853	_ARLSYS(ph)DK_
PRKCH	Ubiquitylation	K36	-0.644		_K(gl)GHQLLDPYLTVSVDQVR_
PRKCH	Ubiquitylation	K152	1.064		_IFK(gl)HFTR_
PRKCH	Phosphorylation	S317	-0.562	-0.534	_TLAGMGLQPGNIS(ph)PTSK_
PRKCH	Phosphorylation	T656	-0.471		_SREDVSNFDPDFIKEEPVLT(ph)PIDEGHLPM(ox)INQDEFR_
PRKCQ	Phosphorylation	S685		0.911	_ALINS(ph)MDQNMFR_
RAF1	Phosphorylation	S29	0.028	-0.571	_DAVFDGSSCIS(ph)PTIVQQFGYQR_
RAF1	Phosphorylation	T31	0.028	-0.669	_DAVFDGSSCIS(ph)PTIVQQFGYQR_
RAF1	Phosphorylation	S244		0.053	_YSTPHAFTFNTSS(ph)PSSEGSLSQR_
RAF1	Phosphorylation	S259	-0.069	0.054	_STS(ph)TPNVHM(ox)VSTTLPVDSR_
RAF1	Phosphorylation	S301		-0.651	_SHSESASPSALSSSPNNLS(ph)PTGWSQPK_
RAF1	Phosphorylation	T303		-0.664	_SHSESASPSALSSSPNNLSPT(ph)GWSQPK_
RAF1	Phosphorylation	S497		-0.449	_SRWS(ph)GSQQVEQPTGSVLWMAPEVIR_
RAF1	Phosphorylation	S621	0.212	0.271	_SAS(ph)EPSLHR_
RAF1	Phosphorylation	S642	-0.197	0.463	_AAHTEDINACTLTTS(ph)PR_
RPS6KA1	Phosphorylation	S227	0.363	0.496	_AYS(ph)FCGTVEYM(ox)APEVVNR_
RPS6KA1	Phosphorylation	T231	0.315		_KAYSFCGT(ph)VEYMAPEVVNR_
RPS6KA1	Ubiquitylation	K316		-1.156	_LGSGPDGAEEIK(gl)R_
RPS6KA1	Phosphorylation	T359	-0.149	-0.339	_T(ph)PKDSPGIPPSAGAHQLFR_
RPS6KA1	Phosphorylation	S363	-0.711	-0.697	_TPKDS(ph)PGIPPSAGAHQLFR_
RPS6KA1	Ubiquitylation	K566		-0.152	_ICDFGFAK(gl)QLR_
RPS6KA3	Phosphorylation	S227	0.363	0.496	_AYS(ph)FCGTVEYM(ox)APEVVNR_
RPS6KA3	Phosphorylation	T231	0.315		_KAYSFCGT(ph)VEYMAPEVVNR_
RPS6KA3	Ubiquitylation	K322	-0.076	-0.376	_LGAGPDGVEEIK(gl)R_
RPS6KA3	Phosphorylation	T365	-0.892	-1.003	_T(ph)PKDSPGIPPSANAHQLFR_
RPS6KA3	Phosphorylation	S369	-0.621	-0.862	_TPKDS(ph)PGIPPSANAHQLFR_
RPS6KA3	Ubiquitylation	K566		-0.152	_ICDFGFAK(gl)QLR_
RPS6KA3	Phosphorylation	S715	-0.923	-0.880	_NQS(ph)PVLEPVGR_
SOS1	Phosphorylation	S1082	0.278		_IPESETESTASAPNS(ph)PR_
SOS1	Phosphorylation	S1166	0.097	-0.094	_RPESAPAES(ph)SPSK_
TRIO	Phosphorylation	S1723		0.798	_S(ph)SMEMEGIFNHK_
TRIO	Phosphorylation	S1724		0.798	_S(ph)SMEMEGIFNHK_
TRIO	Phosphorylation	S2455	0.012	-0.418	_AGAAS(ph)PLNSPLSSAVPSLGK_
TRIO	Phosphorylation	S2459		0.534	_AGAAS(ph)PLNS(ph)PLSSAVPSLGK_
YWHAB	Ubiquitylation	K11	1.057	1.322	_(ac)TMDKSELVQK(gl)AK_
YWHAB	Ubiquitylation	K13	0.060	0.388	_AK(gl)LAEQAER_
YWHAB	Ubiquitylation	K70	0.558	-0.175	_VISSIEQK(gl)TER_
YWHAB	Ubiquitylation	K140		0.531	_YLSEVASGDNK(gl)QTTVSNSQQAYQEAFEISKK_
YWHAB	Ubiquitylation	K159	0.300		_QTTVSNSQQAYQEAFEISK(gl)K_
YWHAB	Ubiquitylation	K160	-0.439	-0.371	_K(gl)EMQPTHPIR_