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Query: DGKD

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DGKD 1 4.271 -1.930 3.220

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DGKD Phosphorylation S56 0.319 0.732 _KVS(ph)TSGQIR_

Background Information for DGKD:


Pubmed-DGKD »
Uniprot-DGKD »
Biogrid-DGKD »
ProteomicsDB-DGKD »

Tumorportal-DGKD »
COSMIC-DGKD »
GenomeRNAi-DGKD »
Genecards-DGKD


Protein-protein Interactions for DGKD
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ECD Cat. description Hein, Mann, Cell 2015
Category members IP bait EXOSC1;RP11 Cat. description Hein, Mann, Cell 2015
Category members IP bait SPIRE2 Cat. description Hein, Mann, Cell 2015
Category members IP bait FEZ1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DGKD
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PE/DAG-bd IPR002219 0.63
Category members PH_domain IPR001849 0.14
Category members Diacylglycerol_kin_accessory IPR000756 0
Category members Diacylglycerol_kinase_cat_dom IPR001206 0
Category members SAM IPR001660 0
Category members SAM_2 IPR011510 0
Category members SAM/pointed IPR013761 0
Category members SAM_type1 IPR021129 0


Protein complexes (CORUM database) featuring DGKD
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring DGKD
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0015031 protein transport Database 3.48
Category members Pathway Pathway_243 REACTOME_GPCR_DOWNSTREAM_SIGNALING 0 1.27
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_256 REACTOME_SIGNALING_BY_GPCR 0 0.83
Category members Pathway Pathway_71 KEGG_GLYCEROLIPID_METABOLISM 0 0.45
Category members Pathway Pathway_53 REACTOME_HEMOSTASIS 0 0.4
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members GO Category GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway Database 0.36
Category members GO Category GO:0007275 multicellular organismal development Database 0.31
Category members GO Category GO:0006897 endocytosis Database 0.31
Category members GO Category GO:0046982 protein heterodimerization activity Database 0.28
Category members GO Category GO:0007173 epidermal growth factor receptor signaling pathway Database 0.26
Category members Pathway Pathway_485 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS 0 0.18
Category members GO Category GO:0016023 cytoplasmic membrane-bounded vesicle Database 0.17
Category members GO Category GO:0030168 platelet activation Database 0.13
Category members Pathway Pathway_56 REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION 0 0.11
Category members GO Category GO:0019932 second-messenger-mediated signaling Database 0.04
Category members Pathway Pathway_486 REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS 0 0.04
Category members GO Category GO:0004143 diacylglycerol kinase activity Database 0.03
Category members Pathway Pathway_276 KEGG_GLYCEROPHOSPHOLIPID_METABOLISM 0 0
Category members Pathway Pathway_487 REACTOME_GASTRIN_CREB_SIGNALLING_PATHWAY_VIA_PKC_AND_MAPK 0 0
Category members Pathway Pathway_488 KEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM 0 0
Category members GO Category GO:0003951 NAD+ kinase activity Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0010033 response to organic substance Database 0
Category members GO Category GO:0016049 cell growth Database 0
Category members GO Category GO:0019992 diacylglycerol binding Database 0
Category members GO Category GO:0035556 intracellular signal transduction Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0
Category members GO Category GO:0046339 diacylglycerol metabolic process Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0051260 protein homooligomerization Database 0


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