Results for the Category
REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS
(Pathway_485)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| ITPR3 | 2 | -0.190 | -0.500 | 1.489 | 1.835 | |||
| DGKD | 1 | -1.930 | 3.220 | |||||
| PRKCH | 0 | 1.450 | -1.320 | |||||
| PRKCQ | 0 | 0.410 | 0.020 | |||||
| DGKH | 0 | -1.220 | 0.820 | |||||
| ITPR2 | 0 | -1.020 | 0.610 | 0.952 | 0.981 | |||
| DGKE | 0 | -0.800 | 1.500 | -0.239 | 0.518 | |||
| PRKCD | 0 | 0.250 | 0.070 | 0.578 | 0.427 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| DGKD | Phosphorylation | S56 | 0.319 | 0.732 | _KVS(ph)TSGQIR_ |
| DGKE | Ubiquitylation | K212 | -0.965 | _TDYEVLASK(gl)LGK_ | |
| DGKE | Ubiquitylation | K357 | -0.396 | 0.179 | _VQVTNK(gl)GYYNLR_ |
| DGKH | Phosphorylation | S56 | 0.319 | 0.732 | _KVS(ph)TSGQIR_ |
| ITPR2 | Ubiquitylation | K909 | -0.247 | _LSK(gl)FQDGGNNVMR_ | |
| ITPR2 | Phosphorylation | S1160 | 0.443 | 0.895 | _GGEEPIEESNILS(ph)PVQDGTK_ |
| ITPR3 | Ubiquitylation | K529 | 1.377 | _EK(gl)GGEGPLVR_ | |
| ITPR3 | Phosphorylation | S934 | 0.318 | -0.802 | _KQS(ph)VFSAPSLSAGASAAEPLDR_ |
| ITPR3 | Phosphorylation | S937 | -0.026 | _KQSVFS(ph)APSLSAGASAAEPLDR_ | |
| ITPR3 | Ubiquitylation | K1534 | -0.220 | _TLAMVAK(gl)GR_ | |
| ITPR3 | Phosphorylation | S1832 | 0.650 | 0.560 | _VAS(ph)FSIPGSSSR_ |
| ITPR3 | Ubiquitylation | K2597 | -0.819 | _NK(gl)NLDWFPR_ | |
| ITPR3 | Ubiquitylation | K2628 | -0.010 | _ILQDK(gl)LNSTMK_ | |
| ITPR3 | Phosphorylation | S2670 | 1.132 | 1.555 | _LGFVDVQNCIS(ph)R_ |
| PRKCD | Ubiquitylation | K138 | -0.141 | _SEDEAK(gl)FPTMNR_ | |
| PRKCD | Ubiquitylation | K222 | 0.185 | 0.658 | _DTIFQK(gl)ER_ |
| PRKCD | Phosphorylation | S302 | -0.240 | -0.222 | _S(ph)DSASSEPVGIYQGFEK_ |
| PRKCD | Phosphorylation | S304 | 0.378 | 0.289 | _RSDS(ph)ASSEPVGIYQGFEK_ |
| PRKCD | Phosphorylation | S506 | -0.213 | 0.200 | _AS(ph)TFCGTPDYIAPEILQGLK_ |
| PRKCD | Phosphorylation | T507 | -0.149 | 0.240 | _AS(ph)TFCGTPDYIAPEILQGLK_ |
| PRKCD | Ubiquitylation | K641 | -2.000 | _DYSNFDQEFLNEK(gl)AR_ | |
| PRKCD | Phosphorylation | S645 | 0.577 | 0.832 | _ARLS(ph)YSDK_ |
| PRKCD | Phosphorylation | S647 | 0.886 | 0.853 | _ARLSYS(ph)DK_ |
| PRKCH | Ubiquitylation | K36 | -0.644 | _K(gl)GHQLLDPYLTVSVDQVR_ | |
| PRKCH | Ubiquitylation | K152 | 1.064 | _IFK(gl)HFTR_ | |
| PRKCH | Phosphorylation | S317 | -0.562 | -0.534 | _TLAGMGLQPGNIS(ph)PTSK_ |
| PRKCH | Phosphorylation | T656 | -0.471 | _SREDVSNFDPDFIKEEPVLT(ph)PIDEGHLPM(ox)INQDEFR_ | |
| PRKCQ | Phosphorylation | S685 | 0.911 | _ALINS(ph)MDQNMFR_ |
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